| Crystal structure and binding properties of the Serratia marcescens chitin-binding protein CBP21 G Vaaje-Kolstad, DR Houston, AHK Riemen, VGH Eijsink, ... Journal of Biological Chemistry 280 (12), 11313-11319, 2005 | 332 | 2005 |
| Structure of human chitotriosidase: implications for specific inhibitor design and function of mammalian chitinase-like lectins F Fusetti, H Von Moeller, D Houston, HJ Rozeboom, BW Dijkstra, RG Boot, ... Journal of Biological Chemistry 277 (28), 25537-25544, 2002 | 290 | 2002 |
| Consensus docking: improving the reliability of docking in a virtual screening context DR Houston, MD Walkinshaw Journal of chemical information and modeling 53 (2), 384-390, 2013 | 231 | 2013 |
| Structure-based exploration of cyclic dipeptide chitinase inhibitors DR Houston, B Synstad, VGH Eijsink, MJR Stark, IM Eggleston, ... Journal of medicinal chemistry 47 (23), 5713-5720, 2004 | 181 | 2004 |
| Structure and ligand-induced conformational change of the 39-kDa glycoprotein from human articular chondrocytes DR Houston, AD Recklies, JC Krupa, DMF Van Aalten Journal of Biological Chemistry 278 (32), 30206-30212, 2003 | 181 | 2003 |
| Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases FV Rao, DR Houston, RG Boot, JMFG Aerts, M Hodkinson, DJ Adams, ... Chemistry & biology 12 (1), 65-76, 2005 | 130 | 2005 |
| High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: mimicry of carbohydrate substrate DR Houston, K Shiomi, N Arai, S Ōmura, MG Peter, A Turberg, B Synstad, ... Proceedings of the National Academy of Sciences 99 (14), 9127-9132, 2002 | 123 | 2002 |
| Oligopeptide signaling through TbGPR89 drives trypanosome quorum sensing F Rojas, E Silvester, J Young, R Milne, M Tettey, DR Houston, ... Cell 176 (1), 306-317. e16, 2019 | 119 | 2019 |
| Crystal structures of allosamidin derivatives in complex with human macrophage chitinase FV Rao, DR Houston, RG Boot, JMFG Aerts, S Sakuda, DMF Van Aalten Journal of Biological Chemistry 278 (22), 20110-20116, 2003 | 98 | 2003 |
| Structure of the D142N mutant of the family 18 chitinase ChiB from Serratia marcescens and its complex with allosamidin G Vaaje-Kolstad, DR Houston, FV Rao, MG Peter, B Synstad, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1696 (1), 103-111, 2004 | 80 | 2004 |
| Inhibition of the ERCC1–XPF structure-specific endonuclease to overcome cancer chemoresistance EM McNeil, KR Astell, AM Ritchie, S Shave, DR Houston, P Bakrania, ... DNA repair 31, 19-28, 2015 | 71 | 2015 |
| The cyclic dipeptide CI-4 [cyclo-(l-Arg-d-Pro)] inhibits family 18 chitinases by structural mimicry of a reaction intermediate DR Houston, I Eggleston, B SYNSTAD, VGH Eijsink, DMF AALTEN Biochemical Journal 368 (1), 23-27, 2002 | 71 | 2002 |
| Artemisinin resistance in rodent malaria-mutation in the AP2 adaptor μ-chain suggests involvement of endocytosis and membrane protein trafficking G Henriques, A Martinelli, L Rodrigues, K Modrzynska, R Fawcett, ... Malaria journal 12 (1), 1-15, 2013 | 68 | 2013 |
| Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono-δ-lactone G Vaaje-Kolstad, A Vasella, MG Peter, C Netter, DR Houston, ... Journal of Biological Chemistry 279 (5), 3612-3619, 2004 | 66 | 2004 |
| Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono-δ-lactone G Vaaje-Kolstad, A Vasella, MG Peter, C Netter, DR Houston, ... Journal of Biological Chemistry 279 (5), 3612-3619, 2004 | 66 | 2004 |
| Intrinsic lipid binding activity of ATG 16L1 supports efficient membrane anchoring and autophagy LJ Dudley, AG Cabodevilla, AN Makar, M Sztacho, T Michelberger, ... The EMBO journal 38 (9), e100554, 2019 | 59 | 2019 |
| Hetero‐trans‐β‐glucanase, an enzyme unique to Equisetum plants, functionalizes cellulose TJ Simmons, KE Mohler, C Holland, F Goubet, L Franková, DR Houston, ... The Plant Journal 83 (5), 753-769, 2015 | 52 | 2015 |
| Identification and Characterization of a Protein-tyrosine Phosphatase in Leishmania M Nascimento, WW Zhang, A Ghosh, DR Houston, AM Berghuis, M Olivier, ... Journal of Biological Chemistry 281 (47), 36257-36268, 2006 | 52 | 2006 |
| Rapid discovery and structure–activity relationships of pyrazolopyrimidines that potently suppress breast cancer cell growth via SRC kinase inhibition with exceptional … C Fraser, JC Dawson, R Dowling, DR Houston, JT Weiss, AF Munro, ... Journal of medicinal chemistry 59 (10), 4697-4710, 2016 | 50 | 2016 |
| Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity AA Makarov, J Zou, DR Houston, C Spanos, AS Solovyova, ... Nature communications 10 (1), 3056, 2019 | 46 | 2019 |
malcolm walkinshawThe University of EdinburghVerified email at ed.ac.uk
