The human intestinal cytochrome P450 “pie” MF Paine, HL Hart, SS Ludington, RL Haining, AE Rettie, DC Zeldin Drug metabolism and disposition 34 (5), 880-886, 2006 | 1031 | 2006 |
Genetic association between sensitivity to warfarin and expression of CYP2C9* 3 DJ Steward, RL Haining, KR Henne, G Davis, TH Rushmore, WF Trager, ... Pharmacogenetics and Genomics 7 (5), 361-367, 1997 | 382 | 1997 |
Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral … RL Haining, AP Hunter, ME Veronese, WF Trager, AE Rettie Archives of biochemistry and biophysics 333 (2), 447-458, 1996 | 337 | 1996 |
Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CYP2D6 and CYP3A activities? A Yu, RL Haining Drug Metabolism and Disposition 29 (11), 1514-1520, 2001 | 195 | 2001 |
Involvement of human cytochrome P450 2D6 in the bioactivation of acetaminophen H Dong, RL Haining, KE Thummel, AE Rettie, SD Nelson Drug metabolism and disposition 28 (12), 1397-1400, 2000 | 192 | 2000 |
A common genetic basis for idiosyncratic toxicity of warfarin and phenytoin AE Rettie, RL Haining, M Bajpai, RH Levy Epilepsy research 35 (3), 253-255, 1999 | 143 | 1999 |
CYP2C-catalyzed delta (9)-tetrahydrocannabinol metabolism: Kinetics, pharmacogenetics and interaction with phenytoin TM Bland, RL Haining, TS Tracy, PS Callery Biochemical pharmacology 70 (7), 1096-1103, 2005 | 134 | 2005 |
Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6. 1, 2D6. 2, 2D6. 10, and 2D6. 17 allelic isoforms A Yu, BM Kneller, AE Rettie, RL Haining Journal of Pharmacology and Experimental Therapeutics 303 (3), 1291-1300, 2002 | 125 | 2002 |
Enzymatic determinants of the substrate specificity of CYP2C9: role of B ‘− C loop residues in providing the π-stacking anchor site for warfarin binding RL Haining, JP Jones, KR Henne, MB Fisher, DR Koop, WF Trager, ... Biochemistry 38 (11), 3285-3292, 1999 | 124 | 1999 |
Electrospray ionization mass spectrometric analysis of intact cytochrome P450: identification of tienilic acid adducts to P450 2C9 LL Koenigs, RM Peter, AP Hunter, RL Haining, AE Rettie, T Friedberg, ... Biochemistry 38 (8), 2312-2319, 1999 | 117 | 1999 |
Polymorphic variants (CYP2C9* 3 and CYP2C9* 5) and the F114L active site mutation of CYP2C9: effect on atypical kinetic metabolism profiles TS Tracy, JM Hutzler, RL Haining, AE Rettie, MA Hummel, LJ Dickmann Drug Metabolism and Disposition 30 (4), 385-390, 2002 | 115 | 2002 |
Neuromelanin, one of the most overlooked molecules in modern medicine, is not a spectator RL Haining, C Achat-Mendes Neural regeneration research 12 (3), 372-375, 2017 | 108 | 2017 |
(+)-N-3-Benzyl-nirvanol and (−)-N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19 H Suzuki, MB Kneller, RL Haining, WF Trager, AE Rettie Drug Metabolism and Disposition 30 (3), 235-239, 2002 | 107 | 2002 |
N-oxygenation of clozapine by flavin-containing monooxygenase M Tugnait, EM Hawes, G McKay, AE Rettie, RL Haining, KK Midha Drug Metabolism and Disposition 25 (4), 524-527, 1997 | 97 | 1997 |
Reduced (±)-3,4-methylenedioxymethamphetamine (“Ecstasy”) metabolism with cytochrome P450 2D6 inhibitors and pharmacogenetic variants in vitro Y Ramamoorthy, A Yu, N Suh, RL Haining, RF Tyndale, EM Sellers Biochemical pharmacology 63 (12), 2111-2119, 2002 | 89 | 2002 |
Characterization of Dextromethorphan O-andN-Demethylation Catalyzed by Highly Purified Recombinant Human CYP2D6 A Yu, H Dong, D Lang, RL Haining Drug metabolism and disposition 29 (11), 1362-1365, 2001 | 66 | 2001 |
Flunitrazepam metabolism by cytochrome P450S 2C19 and 3A4 T Kilicarslan, RL Haining, AE Rettie, U Busto, RF Tyndale, EM Sellers Drug metabolism and disposition 29 (4), 460-465, 2001 | 60 | 2001 |
The relative contribution of monoamine oxidase and cytochrome p450 isozymes to the metabolic deamination of the trace amine tryptamine AM Yu, CP Granvil, RL Haining, KW Krausz, J Corchero, A Küpfer, JR Idle, ... Journal of Pharmacology and Experimental Therapeutics 304 (2), 539-546, 2003 | 59 | 2003 |
Baculovirus-mediated expression and purification of human FMO3: catalytic, immunochemical, and structural characterization RL Haining, AP Hunter, AJM Sadeque, RM Philpot, AE Rettie Drug metabolism and disposition 25 (7), 790-0797, 1997 | 59 | 1997 |
Bridging the undergraduate curriculum using an integrated course-embedded undergraduate research experience (ICURE) JE Russell, AR D’Costa, C Runck, DW Barnes, AL Barrera, ... CBE—Life Sciences Education 14 (1), ar4, 2015 | 54 | 2015 |