| Distinct signaling of coreceptors regulates specific metabolism pathways and impacts memory development in CAR T cells OU Kawalekar, RS O’Connor, JA Fraietta, L Guo, SE McGettigan, ... Immunity 44 (2), 380-390, 2016 | 1073 | 2016 |
| Foxp3 reprograms T cell metabolism to function in low-glucose, high-lactate environments A Angelin, L Gil-de-Gómez, S Dahiya, J Jiao, L Guo, MH Levine, Z Wang, ... Cell metabolism 25 (6), 1282-1293. e7, 2017 | 904 | 2017 |
| Regulation of cardiovascular development and integrity by the heart of glass–cerebral cavernous malformation protein pathway B Kleaveland, X Zheng, JJ Liu, Y Blum, JJ Tung, Z Zou, SM Sweeney, ... Nature medicine 15 (2), 169-176, 2009 | 253 | 2009 |
| A cellular system that degrades misfolded proteins and protects against neurodegeneration L Guo, BI Giasson, A Glavis-Bloom, MD Brewer, J Shorter, AD Gitler, ... Molecular cell 55 (1), 15-30, 2014 | 201 | 2014 |
| Mechanism of antineoplastic activity of lonidamine K Nath, L Guo, B Nancolas, DS Nelson, AA Shestov, SC Lee, J Roman, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1866 (2), 151-162, 2016 | 179 | 2016 |
| Inhibition of mitochondrial complex II by the anticancer agent lonidamine L Guo, AA Shestov, AJ Worth, K Nath, DS Nelson, DB Leeper, ... Journal of Biological Chemistry 291 (1), 42-57, 2016 | 170 | 2016 |
| Lactate limits T cell proliferation via the NAD (H) redox state WJ Quinn, J Jiao, T TeSlaa, J Stadanlick, Z Wang, L Wang, T Akimova, ... Cell reports 33 (11), 2020 | 167 | 2020 |
| The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations RS O’Connor, L Guo, S Ghassemi, NW Snyder, AJ Worth, L Weng, Y Kam, ... Scientific reports 8 (1), 6289, 2018 | 153 | 2018 |
| The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters B Nancolas, L Guo, R Zhou, K Nath, DS Nelson, DB Leeper, IA Blair, ... Biochemical Journal 473 (7), 929-936, 2016 | 119 | 2016 |
| Enhanced degradation of misfolded proteins promotes tumorigenesis L Chen, MD Brewer, L Guo, R Wang, P Jiang, X Yang Cell reports 18 (13), 3143-3154, 2017 | 102 | 2017 |
| Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality A Saha, RS O’Connor, G Thangavelu, SB Lovitch, DB Dandamudi, ... The Journal of clinical investigation 126 (7), 2642-2660, 2016 | 95 | 2016 |
| Blood flow reprograms lymphatic vessels to blood vessels CY Chen, C Bertozzi, Z Zou, L Yuan, JS Lee, MM Lu, SJ Stachelek, ... The Journal of clinical investigation 122 (6), 2006-2017, 2012 | 87 | 2012 |
| Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells Y Xu, Y Zhang, JC García-Cañaveras, L Guo, M Kan, S Yu, IA Blair, ... Science 369 (6502), 397-403, 2020 | 61 | 2020 |
| Differential reliance on lipid metabolism as a salvage pathway underlies functional differences of T cell subsets in poor nutrient environments C Ecker, L Guo, S Voicu, L Gil-de-Gómez, A Medvec, L Cortina, J Pajda, ... Cell reports 23 (3), 741-755, 2018 | 61 | 2018 |
| Stabilized human TRIM5α protects human T cells from HIV-1 infection MW Richardson, L Guo, F Xin, X Yang, JL Riley Molecular Therapy 22 (6), 1084-1095, 2014 | 54 | 2014 |
| Upregulation of antioxidant capacity and nucleotide precursor availability suffices for oncogenic transformation Y Zhang, Y Xu, W Lu, JM Ghergurovich, L Guo, IA Blair, JD Rabinowitz, ... Cell metabolism 33 (1), 94-109. e8, 2021 | 45 | 2021 |
| Diisopropylethylamine/hexafluoroisopropanol‐mediated ion‐pairing ultra‐high‐performance liquid chromatography/mass spectrometry for phosphate and carboxylate metabolite … L Guo, AJ Worth, C Mesaros, NW Snyder, JD Glickson, IA Blair Rapid Communications in Mass Spectrometry 30 (16), 1835-1845, 2016 | 45 | 2016 |
| TRIM11 prevents and reverses protein aggregation and rescues a mouse model of Parkinson’s disease G Zhu, DS Harischandra, S Ghaisas, P Zhang, W Prall, L Huang, ... Cell reports 33 (9), 2020 | 44 | 2020 |
| Liquid chromatography-high resolution mass spectrometry analysis of platelet frataxin as a protein biomarker for the rare disease Friedreich’s Ataxia L Guo, Q Wang, L Weng, LA Hauser, CJ Strawser, AG Rocha, A Dancis, ... Analytical chemistry 90 (3), 2216-2223, 2018 | 40 | 2018 |
| Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer B Zhou, H Xu, M Xia, C Sun, N Li, E Guo, L Guo, W Shan, H Lu, Y Wu, Y Li, ... Frontiers of medicine 11, 214-222, 2017 | 40 | 2017 |
