Matthias Festag
Matthias Festag
Patvirtintas el. paštas
A European pharmaceutical company initiative challenging the regulatory requirement for acute toxicity studies in pharmaceutical drug development
S Robinson, JL Delongeas, E Donald, D Dreher, M Festag, S Kervyn, ...
Regulatory Toxicology and Pharmacology 50 (3), 345-352, 2008
An in vitro embryotoxicity assay based on the disturbance of the differentiation of murine embryonic stem cells into endothelial cells. I: Establishment of the differentiation …
M Festag, C Sehner, P Steinberg, B Viertel
Toxicology in Vitro 21 (8), 1619-1630, 2007
A global pharmaceutical company initiative: An evidence-based approach to define the upper limit of body weight loss in short term toxicity studies
K Chapman, F Sewell, L Allais, JL Delongeas, E Donald, M Festag, ...
Regulatory Toxicology and Pharmacology 67 (1), 27-38, 2013
Characterization of a re-engineered, mesothelin-targeted Pseudomonas exotoxin fusion protein for lung cancer therapy
F Bauss, M Lechmann, BF Krippendorff, R Staack, F Herting, M Festag, ...
Molecular oncology 10 (8), 1317-1329, 2016
Inhibition of EGF uptake by nephrotoxic antisense drugs in vitro and implications for preclinical safety profiling
A Moisan, M Gubler, JD Zhang, Y Tessier, KD Erichsen, S Sewing, ...
Molecular Therapy-Nucleic Acids 6, 89-105, 2017
Pediatric safety of polysorbates in drug formulations
C Kriegel, M Festag, RSK Kishore, D Roethlisberger, G Schmitt
Children 7 (1), 1, 2020
Recommendations from a global cross-company data sharing initiative on the incorporation of recovery phase animals in safety assessment studies to support first-in-human …
F Sewell, K Chapman, P Baldrick, D Brewster, A Broadmeadow, P Brown, ...
Regulatory Toxicology and Pharmacology 70 (1), 413-429, 2014
Assessment of the Genotoxic Potential of Azidothymidine in the Comet, Micronucleus, and Pig-a Assay
M Guérard, J Koenig, M Festag, SD Dertinger, T Singer, G Schmitt, ...
toxicological sciences 135 (2), 309-316, 2013
Interspecies variation of outer retina and choriocapillaris imaged with optical coherence tomography
P Soukup, P Maloca, B Altmann, M Festag, EA Atzpodien, S Pot
Investigative ophthalmology & visual science 60 (10), 3332-3342, 2019
From the cover: The minipig is a suitable Non-Rodent model in the safety assessment of single stranded oligonucleotides
A Braendli-Baiocco, M Festag, K Dumong Erichsen, R Persson, ...
Toxicological Sciences 157 (1), 112-128, 2017
Vehicle systems and excipients used in minipig drug development studies
ML Weaver, AB Grossi, J Schützsack, J Parish, J Løgsted, IB Bøgh, ...
Toxicologic Pathology 44 (3), 367-372, 2016
Assessment of preclinical liver and skeletal muscle biomarkers following clofibrate administration in Wistar rats
P Maliver, M Festag, M Bennecke, F Christen, B Bánfai, B Lenz, M Winter
Toxicologic pathology 45 (4), 506-525, 2017
Safety, tissue distribution, and metabolism of LNA-containing antisense oligonucleotides in rats
F Romero-Palomo, M Festag, B Lenz, S Schadt, A Brink, A Kipar, ...
Toxicologic pathology 49 (6), 1174-1192, 2021
Genotoxicity testing of peptides: folate deprivation as a marker of exaggerated pharmacology
M Guérard, A Zeller, M Festag, C Schubert, T Singer, L Müller
Toxicology and applied pharmacology 279 (3), 419-427, 2014
Morphologic and functional effects of gamma secretase inhibition on splenic marginal zone B cells
MC de Vera Mudry, F Regenass-Lechner, L Ozmen, B Altmann, M Festag, ...
International journal of Alzheimer’s disease 2012, 2012
Effect of 4-chlorobiphenyls as an initiator of rat liver carcinogenesis
P Espandiari, TP Twaroski, M Festag, EY Lee, HP Glauert, LW Robertson
PCBs–Recent Advances in the Environmental Toxicology and Health Effects 399, 2001
Emesis in minipigs and relevance in nonclinical safety testing.
G. Schmitt, M. Festag, S. Roberts
Göttingen Minipigs magazine 63, 6-9, 2022
Cardiovascular effects of RTR2996, a single stranded oligonucleotide, in the minipig
S Roberts, A Greiter-Wilke, D Waiz, R Jenni, C Weile, M Zihlmann, ...
Journal of Pharmacological and Toxicological Methods 99, 106595, 2019
Antisense oligonucleotides–recent advances in preclinical safety assessment
M Festag
Toxicology Letters 295, S23, 2018
Preclinical assessment of a selective and potent γ-secretase inhibitor in a non-rodent species
MCDV Mudry, M Festag, L Müller
Toxicology Letters, S313, 2016
Sistema negali atlikti operacijos. Bandykite vėliau dar kartą.
Straipsniai 1–20