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Medha M. Pathak
Medha M. Pathak
Verified email at uci.edu
Title
Cited by
Cited by
Year
Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells
MM Pathak, JL Nourse, T Tran, J Hwe, J Arulmoli, DTT Le, E Bernardis, ...
Proceedings of the National Academy of Sciences 111 (45), 16148-16153, 2014
5962014
How does voltage open an ion channel?
F Tombola, MM Pathak, EY Isacoff
Annu. Rev. Cell Dev. Biol. 22 (1), 23-52, 2006
3842006
Closing in on the resting state of the Shaker K+ channel
MM Pathak, V Yarov-Yarovoy, G Agarwal, B Roux, P Barth, S Kohout, ...
Neuron 56 (1), 124-140, 2007
3262007
Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores
F Tombola, MM Pathak, EY Isacoff
Neuron 45 (3), 379-388, 2005
3012005
Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing
H Atcha, A Jairaman, JR Holt, VS Meli, RR Nagalla, ...
Nature communications 12 (1), 3256, 2021
2862021
How cells channel their stress: Interplay between Piezo1 and the cytoskeleton
JL Nourse, MM Pathak
Seminars in cell & developmental biology 71, 3-12, 2017
2312017
Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers
KL Ellefsen, JR Holt, AC Chang, JL Nourse, J Arulmoli, AH Mekhdjian, ...
Communications biology 2 (1), 298, 2019
1772019
Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering
J Arulmoli, HJ Wright, DTT Phan, U Sheth, RA Que, GA Botten, M Keating, ...
Acta biomaterialia 43, 122-138, 2016
1732016
The twisted ion-permeation pathway of a resting voltage-sensing domain
F Tombola, MM Pathak, P Gorostiza, EY Isacoff
Nature 445 (7127), 546-549, 2007
1702007
The cooperative voltage sensor motion that gates a potassium channel
M Pathak, L Kurtz, F Tombola, E Isacoff
The Journal of general physiology 125 (1), 57-69, 2005
1502005
Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner
J Arulmoli, MM Pathak, LP McDonnell, JL Nourse, F Tombola, ...
Scientific reports 5 (1), 8499, 2015
1082015
Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
JR Holt, WZ Zeng, EL Evans, SH Woo, S Ma, H Abuwarda, M Loud, ...
Elife 10, e65415, 2021
982021
Voltage-sensing domain of voltage-gated proton channel Hv1 shares mechanism of block with pore domains
L Hong, MM Pathak, IH Kim, D Ta, F Tombola
Neuron 77 (2), 274-287, 2013
972013
How far will you go to sense voltage?
F Tombola, MM Pathak, EY Isacoff
Neuron 48 (5), 719-725, 2005
862005
Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses
A Jairaman, S Othy, JL Dynes, AV Yeromin, A Zavala, ML Greenberg, ...
Science advances 7 (28), eabg5859, 2021
672021
Mechanosensitive ion channel Piezo1 regulates diet-induced adipose inflammation and systemic insulin resistance
C Zhao, Q Sun, L Tang, Y Cao, JL Nourse, MM Pathak, X Lu, Q Yang
Frontiers in endocrinology 10, 373, 2019
562019
Crosstalk between CD11b and Piezo1 mediates macrophage responses to mechanical cues
H Atcha, VS Meli, CT Davis, KT Brumm, S Anis, J Chin, K Jiang, ...
Frontiers in immunology 12, 689397, 2021
542021
Membrane biophysics define neuron and astrocyte progenitors in the neural lineage
JL Nourse, JL Prieto, AR Dickson, J Lu, MM Pathak, F Tombola, ...
Stem Cells 32 (3), 706-716, 2014
502014
Mechanobiology of neural development
H Abuwarda, MM Pathak
Current opinion in cell biology 66, 104-111, 2020
412020
Membrane curvature governs the distribution of Piezo1 in live cells
S Yang, X Miao, S Arnold, B Li, AT Ly, H Wang, M Wang, X Guo, ...
Nature communications 13 (1), 7467, 2022
352022
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