Promoting transparency and reproducibility in enhanced molecular simulations M Bonomi, G Bussi, C Camilloni, GA Tribello, P Banáš, A Barducci, ... Nature methods 16 (8), 670-673, 2019 | 811 | 2019 |
Principles of protein structural ensemble determination M Bonomi, GT Heller, C Camilloni, M Vendruscolo Current Opinion in Structural Biology 42, 106-116, 2017 | 335 | 2017 |
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, ... Proceedings of the National Academy of Sciences 114 (6), E1009-E1017, 2017 | 333 | 2017 |
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ... Nature communications 10 (1), 225, 2019 | 155 | 2019 |
Vocabulary, syntax, and narrative development in typically developing children and children with early unilateral brain injury: Early parental talk about the “there-and-then … ÖE Demir, ML Rowe, G Heller, S Goldin-Meadow, SC Levine Developmental psychology 51 (2), 161, 2015 | 145 | 2015 |
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, ... Science advances 6 (45), eabb5924, 2020 | 138 | 2020 |
Simultaneous quantification of protein order and disorder P Sormanni, D Piovesan, GT Heller, M Bonomi, P Kukic, C Camilloni, ... Nature chemical biology 13 (4), 339-342, 2017 | 126 | 2017 |
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, ... ACS chemical biology 13 (8), 2308-2319, 2018 | 119 | 2018 |
Targeting disordered proteins with small molecules using entropy GT Heller, P Sormanni, M Vendruscolo Trends in biochemical sciences 40 (9), 491-496, 2015 | 111 | 2015 |
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers FA Aprile, P Sormanni, M Podpolny, S Chhangur, LM Needham, ... Proceedings of the National Academy of Sciences 117 (24), 13509-13518, 2020 | 81 | 2020 |
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide GT Heller, FA Aprile, M Bonomi, C Camilloni, A De Simone, ... Journal of Molecular Biology 429 (18), 2772-2779, 2017 | 71 | 2017 |
Methods of probing the interactions between small molecules and disordered proteins GT Heller, FA Aprile, M Vendruscolo Cellular and Molecular Life Sciences 74, 3225-3243, 2017 | 68 | 2017 |
Determination of Structural Ensembles of Proteins: Restraining vs Reweighting R Rangan, M Bonomi, GT Heller, A Cesari, G Bussi, M Vendruscolo Journal of chemical theory and computation 14 (12), 6632-6641, 2018 | 67 | 2018 |
Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors TCT Michaels, A Šarić, G Meisl, GT Heller, S Curk, P Arosio, S Linse, ... Proceedings of the National Academy of Sciences 117 (39), 24251-24257, 2020 | 66 | 2020 |
Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors TCT Michaels, A Šarić, G Meisl, GT Heller, S Curk, P Arosio, S Linse, ... Proceedings of the National Academy of Sciences 117 (39), 24251-24257, 2020 | 66 | 2020 |
Structural ensemble modulation upon small-molecule binding to disordered proteins GT Heller, M Bonomi, M Vendruscolo Journal of molecular biology 430 (16), 2288-2292, 2018 | 64 | 2018 |
Structural ensemble modulation upon small-molecule binding to disordered proteins GT Heller, M Bonomi, M Vendruscolo Journal of molecular biology 430 (16), 2288-2292, 2018 | 64 | 2018 |
A kinetic ensemble of the Alzheimer’s Aβ peptide T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo Nature Computational Science 1 (1), 71-78, 2021 | 51 | 2021 |
A small molecule stabilizes the disordered native state of the Alzheimer’s Aβ Peptide T Löhr, K Kohlhoff, GT Heller, C Camilloni, M Vendruscolo ACS Chemical Neuroscience 13 (12), 1738, 2022 | 29 | 2022 |
Biomolecular NMR spectroscopy in the era of artificial intelligence VK Shukla, GT Heller, DF Hansen Structure 31 (11), 1360-1374, 2023 | 22 | 2023 |