|The phage abortive infection system, ToxIN, functions as a proteinRNA toxinantitoxin pair|
PC Fineran, TR Blower, IJ Foulds, DP Humphreys, KS Lilley, ...
Proceedings of the National Academy of Sciences 106 (3), 894-899, 2009
|Identification and classification of bacterial Type III toxinantitoxin systems encoded in chromosomal and plasmid genomes|
TR Blower, FL Short, F Rao, K Mizuguchi, XY Pei, PC Fineran, BF Luisi, ...
Nucleic acids research 40 (13), 6158-6173, 2012
|Crystal structure and stability of gyrasefluoroquinolone cleaved complexes from Mycobacterium tuberculosis|
TR Blower, BH Williamson, RJ Kerns, JM Berger
Proceedings of the National Academy of Sciences 113 (7), 1706-1713, 2016
|A processed noncoding RNA regulates an altruistic bacterial antiviral system|
TR Blower, XY Pei, FL Short, PC Fineran, DP Humphreys, BF Luisi, ...
Nature structural & molecular biology 18 (2), 185-190, 2011
|Balancing at survival's edge: the structure and adaptive benefits of prokaryotic toxinantitoxin partners|
TR Blower, GPC Salmond, BF Luisi
Current opinion in structural biology 21 (1), 109-118, 2011
|Viral evasion of a bacterial suicide system by RNAbased molecular mimicry enables infectious altruism|
TR Blower, TJ Evans, R Przybilski, PC Fineran, GPC Salmond
Public Library of Science 8 (10), e1003023, 2012
|Mutagenesis and Functional Characterization of the RNA and Protein Components of the toxIN Abortive Infection and Toxin-Antitoxin Locus of Erwinia|
TR Blower, PC Fineran, MJ Johnson, IK Toth, DP Humphreys, ...
Journal of bacteriology 191 (19), 6029-6039, 2009
|Selectivity and self-assembly in the control of a bacterial toxin by an antitoxic noncoding RNA pseudoknot|
FL Short, XY Pei, TR Blower, SL Ong, PC Fineran, BF Luisi, ...
Proceedings of the National Academy of Sciences 110 (3), E241-E249, 2013
|Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase|
KJ Aldred, TR Blower, RJ Kerns, JM Berger, N Osheroff
Proceedings of the National Academy of Sciences 113 (7), E839-E846, 2016
|Evolution of Pectobacterium bacteriophage ΦM1 to escape two bifunctional type III toxin-antitoxin and abortive infection systems through mutations in a single viral gene|
TR Blower, R Chai, R Przybilski, S Chindhy, X Fang, SE Kidman, H Tan, ...
Applied and environmental microbiology 83 (8), e03229-16, 2017
|The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses|
DM Picton, YA Luyten, RD Morgan, A Nelson, DL Smith, DTF Dryden, ...
Nucleic Acids Research 49 (19), 11257-11273, 2021
|Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial proteinRNA toxinantitoxin system|
F Rao, FL Short, JE Voss, TR Blower, AL Orme, TE Whittaker, BF Luisi, ...
Nucleic Acids Research 43 (19), 9529-9540, 2015
|A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems|
Y Cai, B Usher, C Gutierrez, A Tolcan, M Mansour, PC Fineran, C Condon, ...
Science advances 6 (31), eabb6651, 2020
|Mechanism of Action of Mycobacterium tuberculosis Gyrase Inhibitors: A Novel Class of Gyrase Poisons|
EG Gibson, TR Blower, M Cacho, B Bax, JM Berger, N Osheroff
ACS infectious diseases 4 (8), 1211-1222, 2018
|Anticancer RuII and RhIII Piano‐Stool Complexes that are Histone Deacetylase Inhibitors|
JM Cross, TR Blower, N Gallagher, JH Gill, KL Rockley, JW Walton
ChemPlusChem 81 (12), 1276-1280, 2016
|AbiEi binds cooperatively to the type IV abiE toxinantitoxin operator via a positively-charged surface and causes DNA bending and negative autoregulation|
HG Hampton, SA Jackson, RD Fagerlund, AIM Vogel, RL Dy, TR Blower, ...
Journal of molecular biology 430 (8), 1141-1156, 2018
|Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase|
RE Ashley, TR Blower, JM Berger, N Osheroff
Biochemistry 56 (40), 5440-5448, 2017
|A promiscuous antitoxin of bacteriophage T4 ensures successful viral replication|
FL Short, TR Blower, GPC Salmond
Molecular microbiology 83 (4), 665-668, 2012
|A widespread family of WYL-domain transcriptional regulators co-localizes with diverse phage defence systems and islands|
DM Picton, JD Harling-Lee, SJ Duffner, SC Went, RD Morgan, JCD Hinton, ...
Nucleic Acids Research 50 (9), 5191-5207, 2022
|DNA driven self-assembly of micron-sized rods using DNA-grafted bacteriophage fd virions|
RR Unwin, RA Cabanas, T Yanagishima, TR Blower, H Takahashi, ...
Physical Chemistry Chemical Physics 17 (12), 8194-8202, 2015