| Thermodynamic stability of carbonic anhydrase: measurements of binding affinity and stoichiometry using ThermoFluor D Matulis, JK Kranz, FR Salemme, MJ Todd Biochemistry 44 (13), 5258-5266, 2005 | 609 | 2005 |
| Dynamics of the chaperonin ATPase cycle: implications for facilitated protein folding MJ Todd, PV Viitanen, GH Lorimer Science 265 (5172), 659-666, 1994 | 558 | 1994 |
| Enzyme kinetics determined using calorimetry: a general assay for enzyme activity? MJ Todd, J Gomez Analytical biochemistry 296 (2), 179-187, 2001 | 428 | 2001 |
| Chaperonin-facilitated protein folding: optimization of rate and yield by an iterative annealing mechanism. MJ Todd, GH Lorimer, D Thirumalai Proceedings of the National Academy of Sciences 93 (9), 4030-4035, 1996 | 294 | 1996 |
| The structural stability of the HIV-1 protease MJ Todd, N Semo, E Freire Journal of molecular biology 283 (2), 475-488, 1998 | 235 | 1998 |
| Hydrolysis of adenosine 5'-triphosphate by Escherichia coli GroEL: effects of GroES and potassium ion MJ Todd, PV Viitanen, GH Lorimer Biochemistry 32 (33), 8560-8567, 1993 | 220 | 1993 |
| Competitive inhibitors of Klebsiella aerogenes urease: mechanisms of interaction with the nickel active site MJ Todd, RP Hausinger Journal of Biological Chemistry 264 (27), 15835-15842, 1989 | 217 | 1989 |
| On the role of groES in the chaperonin-assisted folding reaction. Three case studies. M Schmidt, J Buchner, MJ Todd, GH Lorimer, PV Viitanen Journal of Biological Chemistry 269 (14), 10304-10311, 1994 | 200 | 1994 |
| Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes A Velazquez-Campoy, MJ Todd, S Vega, E Freire Proceedings of the National Academy of Sciences 98 (11), 6062-6067, 2001 | 194 | 2001 |
| HIV-1 protease inhibitors: enthalpic versus entropic optimization of the binding affinity A Velazquez-Campoy, MJ Todd, E Freire Biochemistry 39 (9), 2201-2207, 2000 | 168 | 2000 |
| Thermodynamic basis of resistance to HIV-1 protease inhibition: calorimetric analysis of the V82F/I84V active site resistant mutant MJ Todd, I Luque, A Velázquez-Campoy, E Freire Biochemistry 39 (39), 11876-11883, 2000 | 155 | 2000 |
| Role of the γ‐phosphate of ATP in triggering protein folding by GroEL–GroES: function, structure and energetics C Chaudhry, GW Farr, MJ Todd, HS Rye, AT Brunger, PD Adams, ... The EMBO Journal, 2003 | 154 | 2003 |
| Purification and characterization of the nickel-containing multicomponent urease from Klebsiella aerogenes. MJ Todd, RP Hausinger Journal of Biological Chemistry 262 (13), 5963-5967, 1987 | 151 | 1987 |
| The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and-2 J Qi, W Lang, JG Geisler, P Wang, I Petrounia, S Mai, C Smith, H Askari, ... Journal of lipid research 53 (6), 1106-1116, 2012 | 128 | 2012 |
| Fluoride inhibition of Klebsiella aerogenes urease: mechanistic implications of a pseudo-uncompetitive, slow-binding inhibitor MJ Todd, RP Hausinger Biochemistry 39 (18), 5389-5396, 2000 | 126 | 2000 |
| Thermodynamic dissection of the binding energetics of KNI-272, a potent HIV-1 protease inhibitor A Velazquez-Campoy, I Luque, MJ Todd, M Milutinovich, Y Kiso, E Freire Protein Science 9 (9), 1801-1809, 2000 | 118 | 2000 |
| Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation RH Scannevin, R Alexander, TM Haarlander, SL Burke, M Singer, C Huo, ... Journal of Biological Chemistry 292 (43), 17963-17974, 2017 | 117 | 2017 |
| Enhancing recombinant protein quality and yield by protein stability profiling TM Mezzasalma, JK Kranz, W Chan, GT Struble, C Schalk-Hihi, ... SLAS Discovery 12 (3), 418-428, 2007 | 115 | 2007 |
| Molecular basis of resistance to HIV-1 protease inhibition: a plausible hypothesis I Luque, MJ Todd, J Gómez, N Semo, E Freire Biochemistry 37 (17), 5791-5797, 1998 | 100 | 1998 |
| Identification and functional analysis of chaperonin 10, the groES homolog from yeast mitochondria. S Rospert, BS Glick, P Jenö, G Schatz, MJ Todd, GH Lorimer, PV Viitanen Proceedings of the National Academy of Sciences 90 (23), 10967-10971, 1993 | 94 | 1993 |
Ernesto FreireHenry Walters Professor, Johns Hopkins UniversityVerified email at jhu.edu
