| Structure of a serpin–protease complex shows inhibition by deformation JA Huntington, RJ Read, RW Carrell Nature 407 (6806), 923-926, 2000 | 1381 | 2000 |
| Structure of the antithrombin–thrombin–heparin ternary complex reveals the antithrombotic mechanism of heparin W Li, DJD Johnson, CT Esmon, JA Huntington Nature structural & molecular biology 11 (9), 857-862, 2004 | 486 | 2004 |
| Structure and properties of ovalbumin JA Huntington, PE Stein Journal of Chromatography B: Biomedical Sciences and Applications 756 (1-2 …, 2001 | 486 | 2001 |
| Directing thrombin DA Lane, H Philippou, JA Huntington Blood 106 (8), 2605-2612, 2005 | 471 | 2005 |
| Serpins in thrombosis, hemostasis and fibrinolysis JC Rau, LM Beaulieu, JA Huntington, FC CHURCH Journal of thrombosis and haemostasis 5, 102-115, 2007 | 459 | 2007 |
| Molecular recognition mechanisms of thrombin JA Huntington Journal of Thrombosis and Haemostasis 3 (8), 1861-1872, 2005 | 349 | 2005 |
| Serpin structure, function and dysfunction JA Huntington Journal of thrombosis and haemostasis 9, 26-34, 2011 | 344 | 2011 |
| How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration A Zhou, JA Huntington, NS Pannu, RW Carrell, RJ Read Nature Structural & Molecular Biology 10 (7), 541-544, 2003 | 327 | 2003 |
| Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization M Yamasaki, W Li, DJD Johnson, JA Huntington Nature 455 (7217), 1255-1258, 2008 | 290 | 2008 |
| Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism TP Baglin, RW Carrell, FC Church, CT Esmon, JA Huntington Proceedings of the National Academy of Sciences 99 (17), 11079-11084, 2002 | 255 | 2002 |
| Antithrombin–S195A factor Xa‐heparin structure reveals the allosteric mechanism of antithrombin activation DJD Johnson, W Li, TE Adams, JA Huntington The EMBO journal 25 (9), 2029-2037, 2006 | 221 | 2006 |
| Mechanisms of glycosaminoglycan activation of the serpins in hemostasis JA Huntington Journal of Thrombosis and Haemostasis 1 (7), 1535-1549, 2003 | 204 | 2003 |
| Crystal structure of thrombin bound to heparin WJ Carter, E Cama, JA Huntington Journal of Biological Chemistry 280 (4), 2745-2749, 2005 | 197 | 2005 |
| Shape-shifting serpins–advantages of a mobile mechanism JA Huntington Trends in biochemical sciences 31 (8), 427-435, 2006 | 177 | 2006 |
| The serpin inhibitory mechanism is critically dependent on the length of the reactive center loop A Zhou, RW Carrell, JA Huntington Journal of Biological Chemistry 276 (29), 27541-27547, 2001 | 172 | 2001 |
| Molecular basis of α1‐antitrypsin deficiency revealed by the structure of a domain‐swapped trimer M Yamasaki, TJ Sendall, MC Pearce, JC Whisstock, JA Huntington EMBO reports 12 (10), 1011-1017, 2011 | 165 | 2011 |
| Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems GA Silverman, JC Whisstock, SP Bottomley, JA Huntington, D Kaiserman, ... Journal of Biological Chemistry 285 (32), 24299-24305, 2010 | 163 | 2010 |
| Mechanism of heparin activation of antithrombin. Evidence for reactive center loop preinsertion with expulsion upon heparin binding JA Huntington, ST Olson, B Fan, PGW Gettins Biochemistry 35 (26), 8495-8503, 1996 | 155 | 1996 |
| A 2.6 Å structure of a serpin polymer and implications for conformational disease JA Huntington, NS Pannu, B Hazes, RJ Read, DA Lomas, RW Carrell Journal of molecular biology 293 (3), 449-455, 1999 | 147 | 1999 |
| Design and characterization of an APC-specific serpin for the treatment of hemophilia SGI Polderdijk, TE Adams, L Ivanciu, RM Camire, TP Baglin, ... Blood, The Journal of the American Society of Hematology 129 (1), 105-113, 2017 | 143 | 2017 |
