| Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson’s disease therapy SY Woo, JH Kim, MK Moon, SH Han, SK Yeon, JW Choi, BK Jang, ... Journal of medicinal chemistry 57 (4), 1473-1487, 2014 | 234 | 2014 |
| Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production H Chun, H Im, YJ Kang, Y Kim, JH Shin, W Won, J Lim, Y Ju, YM Park, ... Nature neuroscience 23 (12), 1555-1566, 2020 | 176 | 2020 |
| Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer’s disease JH Park, YH Ju, JW Choi, HJ Song, BK Jang, J Woo, H Chun, HJ Kim, ... Science advances 5 (3), eaav0316, 2019 | 131 | 2019 |
| α-Pinene, a major constituent of pine tree oils, enhances non-rapid eye movement sleep in mice through GABAA-benzodiazepine receptors H Yang, J Woo, AN Pae, MY Um, NC Cho, KD Park, M Yoon, J Kim, ... Molecular pharmacology 90 (5), 530-539, 2016 | 126 | 2016 |
| Synthesis of 13-(substituted benzyl) berberine and berberrubine derivatives as antifungal agents KD Park, JH Lee, SH Kim, TH Kang, JS Moon, SU Kim Bioorganic & medicinal chemistry letters 16 (15), 3913-3916, 2006 | 105 | 2006 |
| Biological evaluation of anti-influenza viral activity of semi-synthetic catechin derivatives JM Song, KD Park, KH Lee, YH Byun, JH Park, SH Kim, JH Kim, ... Antiviral Research 76 (2), 178-185, 2007 | 98 | 2007 |
| Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers KD Park, R Liu, H Kohn Chemistry & biology 16 (7), 763-772, 2009 | 95 | 2009 |
| Aberrant tonic inhibition of dopaminergic neuronal activity causes motor symptoms in animal models of Parkinson’s disease JY Heo, MH Nam, HH Yoon, J Kim, YJ Hwang, W Won, DH Woo, JA Lee, ... Current Biology 30 (2), 276-291. e9, 2020 | 88 | 2020 |
| Activation of astrocytic μ-opioid receptor causes conditioned place preference MH Nam, KS Han, J Lee, W Won, W Koh, JY Bae, J Woo, J Kim, E Kwong, ... Cell reports 28 (5), 1154-1166. e5, 2019 | 87 | 2019 |
| Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors JW Choi, BK Jang, N Cho, JH Park, SK Yeon, EJ Ju, YS Lee, G Han, ... Bioorganic & Medicinal Chemistry 23 (19), 6486-6496, 2015 | 87 | 2015 |
| In silico docking and electrophysiological characterization of lacosamide binding sites on collapsin response mediator protein-2 identifies a pocket important in modulating … Y Wang, JM Brittain, BW Jarecki, KD Park, SM Wilson, B Wang, R Hale, ... Journal of Biological Chemistry 285 (33), 25296-25307, 2010 | 86 | 2010 |
| Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model S Kim, ANI Viswanath, JH Park, HE Lee, AY Park, JW Choi, HJ Kim, ... Neuropharmacology 167, 107989, 2020 | 80 | 2020 |
| Astrocytes control sensory acuity via tonic inhibition in the thalamus H Kwak, W Koh, S Kim, K Song, JI Shin, JM Lee, EH Lee, JY Bae, GE Ha, ... Neuron 108 (4), 691-706. e10, 2020 | 75 | 2020 |
| CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide A Moutal, X Yang, W Li, KB Gilbraith, S Luo, S Cai, L François-Moutal, ... Pain 158 (12), 2301-2319, 2017 | 75 | 2017 |
| Synthesis and Anticonvulsant Activities of (R)-N-(4′-Substituted)benzyl 2-Acetamido-3-methoxypropionamides C Salomé, E Salomé-Grosjean, KD Park, P Morieux, R Swendiman, ... Journal of medicinal chemistry 53 (3), 1288-1305, 2010 | 72 | 2010 |
| N-Benzylbenzamides: a new class of potent tyrosinase inhibitors SJ Cho, JS Roh, WS Sun, SH Kim, KD Park Bioorganic & medicinal chemistry letters 16 (10), 2682-2684, 2006 | 72 | 2006 |
| Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors KD Park, P Morieux, C Salomé, SW Cotten, O Reamtong, C Eyers, ... Journal of medicinal chemistry 52 (21), 6897-6911, 2009 | 62 | 2009 |
| (S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation … A Moutal, LA Chew, X Yang, Y Wang, SK Yeon, E Telemi, S Meroueh, ... Pain 157 (7), 1448-1463, 2016 | 61 | 2016 |
| (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5 A Moutal, L François-Moutal, S Perez-Miller, K Cottier, LA Chew, SK Yeon, ... Molecular neurobiology 53, 1959-1976, 2016 | 60 | 2016 |
| Development and characterization of novel derivatives of the antiepileptic drug lacosamide that exhibit far greater enhancement in slow inactivation of voltage-gated sodium … Y Wang, KD Park, C Salomé, SM Wilson, JP Stables, R Liu, R Khanna, ... ACS chemical neuroscience 2 (2), 90-106, 2011 | 56 | 2011 |
