Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity RJ Dennis, EJ Taylor, MS Macauley, KA Stubbs, JP Turkenburg, SJ Hart, ... Nature structural & molecular biology 13 (4), 365-371, 2006 | 252 | 2006 |
The copper active site of CBM33 polysaccharide oxygenases GR Hemsworth, EJ Taylor, RQ Kim, RC Gregory, SJ Lewis, JP Turkenburg, ... Journal of the American Chemical Society 135 (16), 6069-6077, 2013 | 228 | 2013 |
Cellvibrio japonicus α-L-arabinanase 43A has a novel five-blade β-propeller fold D Nurizzo, JP Turkenburg, SJ Charnock, SM Roberts, EJ Dodson, ... Nature structural biology 9 (9), 665-668, 2002 | 213 | 2002 |
Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise GE Whitworth, MS Macauley, KA Stubbs, RJ Dennis, EJ Taylor, GJ Davies, ... Journal of the American Chemical Society 129 (3), 635-644, 2007 | 202 | 2007 |
The mechanisms by which family 10 glycoside hydrolases bind decorated substrates G Pell, EJ Taylor, TM Gloster, JP Turkenburg, CMGA Fontes, LMA Ferreira, ... Journal of Biological Chemistry 279 (10), 9597-9605, 2004 | 201 | 2004 |
Crystal structure of levansucrase from the Gram-negative bacterium Gluconacetobacter diazotrophicus C Martínez-Fleites, M Ortíz-Lombardía, T Pons, N Tarbouriech, EJ Taylor, ... Biochemical Journal 390 (1), 19-27, 2005 | 195 | 2005 |
Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases EJ Taylor, TM Gloster, JP Turkenburg, F Vincent, AM Brzozowski, ... Journal of Biological Chemistry 281 (16), 10968-10975, 2006 | 142 | 2006 |
Structural insight into the ligand specificity of a thermostable family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum EJ Taylor, NL Smith, JP Turkenburg, S D'souza, HJ Gilbert, GJ Davies Biochemical Journal 395 (1), 31-37, 2006 | 123 | 2006 |
Haploinsufficiency of the NOTCH1 receptor as a cause of Adams–Oliver syndrome with variable cardiac anomalies L Southgate, M Sukalo, ASV Karountzos, EJ Taylor, CS Collinson, ... Circulation: Cardiovascular Genetics 8 (4), 572-581, 2015 | 112 | 2015 |
Tailored catalysts for plant cell-wall degradation: redesigning the exo/endo preference of Cellvibrio japonicus arabinanase 43A MR Proctor, EJ Taylor, D Nurizzo, JP Turkenburg, RM Lloyd, M Vardakou, ... Proceedings of the National Academy of Sciences 102 (8), 2697-2702, 2005 | 103 | 2005 |
Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant … A Parmar, R Lakshminarayanan, A Iyer, V Mayandi, ET Leng Goh, ... Journal of medicinal chemistry 61 (5), 2009-2017, 2018 | 97 | 2018 |
Efficient total syntheses and biological activities of two teixobactin analogues A Parmar, A Iyer, CS Vincent, D Van Lysebetten, SH Prior, A Madder, ... Chemical communications 52 (36), 6060-6063, 2016 | 97 | 2016 |
Structural dissection and high-throughput screening of mannosylglycerate synthase J Flint, E Taylor, M Yang, DN Bolam, LE Tailford, C Martinez-Fleites, ... Nature structural & molecular biology 12 (7), 608-614, 2005 | 97 | 2005 |
Crystal structures of Clostridium thermocellum xyloglucanase, XGH74A, reveal the structural basis for xyloglucan recognition and degradation C Martinez-Fleites, CIPD Guerreiro, MJ Baumann, EJ Taylor, JAM Prates, ... Journal of Biological Chemistry 281 (34), 24922-24933, 2006 | 93 | 2006 |
Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded β-helix NL Smith, EJ Taylor, AM Lindsay, SJ Charnock, JP Turkenburg, ... Proceedings of the National Academy of Sciences 102 (49), 17652-17657, 2005 | 93 | 2005 |
How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: structure and activity of a Clostridium thermocellum lichenase, CtLic26A EJ Taylor, A Goyal, CIPD Guerreiro, JAM Prates, VA Money, N Ferry, ... Journal of Biological Chemistry 280 (38), 32761-32767, 2005 | 93 | 2005 |
Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding A Parmar, A Iyer, SH Prior, DG Lloyd, ETL Goh, CS Vincent, ... Chemical Science 8 (12), 8183-8192, 2017 | 64 | 2017 |
The use of forced protein evolution to investigate and improve stability of family 10 xylanases: the production of Ca2+-independent stable xylanases SR Andrews, EJ Taylor, G Pell, F Vincent, VMA Ducros, GJ Davies, ... Journal of Biological Chemistry 279 (52), 54369-54379, 2004 | 62 | 2004 |
Structure and kinetic investigation of Streptococcus pyogenes family GH38 α-mannosidase MDL Suits, Y Zhu, EJ Taylor, J Walton, DL Zechel, HJ Gilbert, GJ Davies PLoS One 5 (2), e9006, 2010 | 61 | 2010 |
Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities A Parmar, SH Prior, A Iyer, CS Vincent, D Van Lysebetten, E Breukink, ... Chemical Communications 53 (12), 2016-2019, 2017 | 57 | 2017 |