| The Warburg effect: how does it benefit cancer cells? MV Liberti, JW Locasale Trends in biochemical sciences 41 (3), 211-218, 2016 | 3433 | 2016 |
| Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ... Cell 149 (3), 656-670, 2012 | 1801 | 2012 |
| Serine, glycine and one-carbon units: cancer metabolism in full circle JW Locasale Nature Reviews Cancer 13 (8), 572-583, 2013 | 1366 | 2013 |
| Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses D Anastasiou, G Poulogiannis, JM Asara, MB Boxer, J Jiang, M Shen, ... Science 334 (6060), 1278-1283, 2011 | 1130 | 2011 |
| Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ... Cell 162 (6), 1217-1228, 2015 | 1086 | 2015 |
| Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ... Nature genetics 43 (9), 869-874, 2011 | 1081 | 2011 |
| Evidence for an alternative glycolytic pathway in rapidly proliferating cells MG Vander Heiden, JW Locasale, KD Swanson, H Sharfi, GJ Heffron, ... Science 329 (5998), 1492-1499, 2010 | 709 | 2010 |
| Influence of threonine metabolism on S-adenosylmethionine and histone methylation N Shyh-Chang, JW Locasale, CA Lyssiotis, Y Zheng, RY Teo, ... Science 339 (6116), 222-226, 2013 | 608 | 2013 |
| Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 582 | 2015 |
| A roadmap for interpreting 13C metabolite labeling patterns from cells JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ... Current opinion in biotechnology 34, 189-201, 2015 | 541 | 2015 |
| Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism SJ Mentch, M Mehrmohamadi, L Huang, X Liu, D Gupta, D Mattocks, ... Cell metabolism 22 (5), 861-873, 2015 | 491 | 2015 |
| Glutamine metabolism in cancer: understanding the heterogeneity AA Cluntun, MJ Lukey, RA Cerione, JW Locasale Trends in cancer 3 (3), 169-180, 2017 | 462 | 2017 |
| Metabolic flux and the regulation of mammalian cell growth JW Locasale, LC Cantley Cell metabolism 14 (4), 443-451, 2011 | 458 | 2011 |
| Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression VA Gerriets, RJ Kishton, MO Johnson, S Cohen, PJ Siska, AG Nichols, ... Nature immunology 17 (12), 1459-1466, 2016 | 401 | 2016 |
| Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism MO Johnson, MM Wolf, MZ Madden, G Andrejeva, A Sugiura, ... Cell 175 (7), 1780-1795. e19, 2018 | 393 | 2018 |
| Heterogeneity of tumor-induced gene expression changes in the human metabolic network J Hu, JW Locasale, JH Bielas, J O'sullivan, K Sheahan, LC Cantley, ... Nature biotechnology 31 (6), 522-529, 2013 | 386 | 2013 |
| The impact of cellular metabolism on chromatin dynamics and epigenetics MA Reid, Z Dai, JW Locasale Nature cell biology 19 (11), 1298-1306, 2017 | 378 | 2017 |
| Dietary methionine influences therapy in mouse cancer models and alters human metabolism X Gao, SM Sanderson, Z Dai, MA Reid, DE Cooper, M Lu, JP Richie Jr, ... Nature 572 (7769), 397-401, 2019 | 370 | 2019 |
| Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis OG McDonald, X Li, T Saunders, R Tryggvadottir, SJ Mentch, ... Nature genetics 49 (3), 367-376, 2017 | 365 | 2017 |
| T cell stemness and dysfunction in tumors are triggered by a common mechanism SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ... Science 363 (6434), eaau0135, 2019 | 322 | 2019 |
Lewis CantleyDana Farber Cancer Center and Harvard Medical SchoolVerified email at med.cornell.edu
