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Vincent J. Hilser
Vincent J. Hilser
Professor and Chair, Department of Biology, Johns Hopkins University
Verified email at jhu.edu - Homepage
Title
Cited by
Cited by
Year
The ensemble nature of allostery
HN Motlagh, JO Wrabl, J Li, VJ Hilser
Nature 508 (7496), 331-339, 2014
12322014
The heat capacity of proteins
J Gomez, VJ Hilser, D Xie, E Freire
Proteins: Structure, Function, and Bioinformatics 22 (4), 404-412, 1995
5401995
Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins
VJ Hilser, EB Thompson
Proceedings of the National Academy of Sciences 104 (20), 8311-8315, 2007
4632007
The magnitude of the backbone conformational entropy change in protein folding
JA D'aquino, J Gómez, VJ Hilser, KH Lee, LM Amzel, E Freire
Proteins: Structure, Function, and Bioinformatics 25 (2), 143-156, 1996
3621996
Structural and energetic basis of allostery
VJ Hilser, JO Wrabl, HN Motlagh
Annual review of biophysics 41, 585-609, 2012
3272012
Structure-based calculation of the equilibrium folding pathway of proteins. Correlation with hydrogen exchange protection factors
VJ Hilser, E Freire
Journal of molecular biology 262 (5), 756-772, 1996
3251996
Allostery in its many disguises: from theory to applications
SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky, A Horovitz, J Li, ...
Structure 27 (4), 566-578, 2019
2992019
Binding sites in Escherichia coli dihydrofolate reductase communicate by modulating the conformational ensemble
H Pan, JC Lee, VJ Hilser
Proceedings of the National Academy of Sciences 97 (22), 12020-12025, 2000
2582000
The structural distribution of cooperative interactions in proteins: analysis of the native state ensemble
VJ Hilser, D Dowdy, TG Oas, E Freire
Proceedings of the National Academy of Sciences 95 (17), 9903-9908, 1998
2501998
A statistical thermodynamic model of the protein ensemble
VJ Hilser, B García-Moreno E, TG Oas, G Kapp, ST Whitten
Chemical reviews 106 (5), 1545-1558, 2006
2312006
Local conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins
ST Whitten, B García-Moreno E, VJ Hilser
Proceedings of the National Academy of Sciences 102 (12), 4282-4287, 2005
1902005
The enthalpy change in protein folding and binding: Refinement of parameters for structure‐based calculations
VJ Hilser, J Gómez, E Freire
Proteins: Structure, Function, and Bioinformatics 26 (2), 123-133, 1996
1811996
Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins
TP Schrank, DW Bolen, VJ Hilser
Proceedings of the National Academy of Sciences 106 (40), 16984-16989, 2009
1772009
Dynamic allostery can drive cold adaptation in enzymes
HG Saavedra, JO Wrabl, JA Anderson, J Li, VJ Hilser
Nature 558 (7709), 324-328, 2018
1712018
Direct access to the cooperative substructure of proteins and the protein ensemble via cold denaturation
CR Babu, VJ Hilser, AJ Wand
Nature structural & molecular biology 11 (4), 352-357, 2004
1662004
An ensemble view of allostery
VJ Hilser
Science 327 (5966), 653-654, 2010
1402010
The role of protein conformational fluctuations in allostery, function, and evolution
JO Wrabl, J Gu, T Liu, TP Schrank, ST Whitten, VJ Hilser
Biophysical chemistry 159 (1), 129-141, 2011
1262011
Agonism/antagonism switching in allosteric ensembles
HN Motlagh, VJ Hilser
Proceedings of the National Academy of Sciences 109 (11), 4134-4139, 2012
1182012
Coupled motion in proteins revealed by pressure perturbation
Y Fu, V Kasinath, VR Moorman, NV Nucci, VJ Hilser, AJ Wand
Journal of the American Chemical Society 134 (20), 8543-8550, 2012
1042012
Predicting the equilibrium protein folding pathway: structure‐based analysis of staphylococcal nuclease
VJ Hilser, E Freire
Proteins: Structure, Function, and Bioinformatics 27 (2), 171-183, 1997
1021997
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