Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements T Karvelis, G Gasiunas, J Young, G Bigelyte, A Silanskas, M Cigan, ... Genome biology 16, 1-13, 2015 | 238 | 2015 |
PAM recognition by miniature CRISPR–Cas12f nucleases triggers programmable double-stranded DNA target cleavage T Karvelis, G Bigelyte, JK Young, Z Hou, R Zedaveinyte, K Budre, ... Nucleic acids research 48 (9), 5016-5023, 2020 | 202 | 2020 |
Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease T Karvelis, G Druteika, G Bigelyte, K Budre, R Zedaveinyte, A Silanskas, ... Nature 599 (7886), 692-696, 2021 | 144 | 2021 |
A catalogue of biochemically diverse CRISPR-Cas9 orthologs G Gasiunas, JK Young, T Karvelis, D Kazlauskas, T Urbaitis, ... Nature communications 11 (1), 5512, 2020 | 127 | 2020 |
Miniature type VF CRISPR-Cas nucleases enable targeted DNA modification in cells G Bigelyte, JK Young, T Karvelis, K Budre, R Zedaveinyte, V Djukanovic, ... Nature communications 12 (1), 6191, 2021 | 57 | 2021 |
A catalogue of biochemically diverse CRISPR-Cas9 orthologs. Nat Commun 11: 5512 G Gasiunas, JK Young, T Karvelis, D Kazlauskas, T Urbaitis, ... | 7 | 2020 |
Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing G Bigelyte, B Duchovska, R Zedaveinyte, G Sasnauskas, T Sinkunas, ... Nucleic Acids Research, gkae016, 2024 | 1 | 2024 |
PAM recognition by miniature CRISPR nucleases triggers programmable double-stranded DNA target cleavage T Karvelis, G Bigelyte, JK Young, Z Hou, R Zedaveinyte, K Budre, ... bioRxiv, 654897, 2019 | 1 | 2019 |
Mechanistic insights into CRISPR-Cas12f1 revealed through single-molecule and biochemical studies JM Marcos, DJ Kauert, S Henkel-Heinecke, P Irmisch, G Bigelyte, ... Biophysical Journal 123 (3), 181a-182a, 2024 | | 2024 |
Dynamics of R-loop formation by CRISPR-Cas12f1 effector complexes S Henkel-Heinecke, G Bigelyte, T Karvelis, V Siksnys, R Seidel Biophysical Journal 121 (3), 477a, 2022 | | 2022 |
Rapid Characterization of Cas9 Protospacer Adjacent Motif Sequence Elements T Karvelis, G Gasiunas, J Young, G Bigelyte, A Silanskas, M Cigan, ... | | |