Martin Noble
Martin Noble
Professor of Structural Biology and Anticancer Drug Design
Verified email at
Cited by
Cited by
Active and inactive protein kinases: structural basis for regulation
LN Johnson, MEM Noble, DJ Owen
Cell 85 (2), 149-158, 1996
Protein kinase inhibitors: insights into drug design from structure
MEM Noble, JA Endicott, LN Johnson
Science 303 (5665), 1800-1805, 2004
Presenting your structures: the CCP4mg molecular-graphics software
S McNicholas, E Potterton, KS Wilson, MEM Noble
Acta Crystallographica Section D: Biological Crystallography 67 (4), 386-394, 2011
Developments in the CCP4 molecular-graphics project
L Potterton, S McNicholas, E Krissinel, J Gruber, K Cowtan, P Emsley, ...
Acta Crystallographica Section D: Biological Crystallography 60 (12), 2288-2294, 2004
The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
NR Brown, MEM Noble, JA Endicott, LN Johnson
Nature cell biology 1 (7), 438-443, 1999
Crystal structure of a Src-homology 3 (SH3) domain
A Musacchio, M Noble, R Pauptit, R Wierenga, M Saraste
Nature 359 (6398), 851-855, 1992
The structural basis for control of eukaryotic protein kinases
JA Endicott, MEM Noble, LN Johnson
Annual review of biochemistry 81, 587-613, 2012
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
A Douangamath, D Fearon, P Gehrtz, T Krojer, P Lukacik, CD Owen, ...
Nature communications 11 (1), 5047, 2020
CCP4i2: the new graphical user interface to the CCP4 program suite
L Potterton, J Agirre, C Ballard, K Cowtan, E Dodson, PR Evans, ...
Acta Crystallographica Section D: Structural Biology 74 (2), 68-84, 2018
Structures of the Cd44–hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction
S Banerji, AJ Wright, M Noble, DJ Mahoney, ID Campbell, AJ Day, ...
Nature structural & molecular biology 14 (3), 234-239, 2007
The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate
MEM Noble, A Cleasby, LN Johnson, MR Egmond, LGJ Frenken
FEBS letters 331 (1-2), 123-128, 1993
A structural explanation for the binding of multiple ligands by the α-adaptin appendage domain
DJ Owen, Y Vallis, MEM Noble, JB Hunter, TR Dafforn, PR Evans, ...
Cell 97 (6), 805-815, 1999
Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2.
AM Lawrie, ME Noble, P Tunnah, NR Brown, LN Johnson, JA Endicott
Nature structural biology 4 (10), 796-801, 1997
Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44
P Teriete, S Banerji, M Noble, CD Blundell, AJ Wright, AR Pickford, ...
Molecular cell 13 (4), 483-496, 2004
Crystal structure of the SH3 domain in human Fyn; comparison of the three‐dimensional structures of SH3 domains in tyrosine kinases and spectrin.
ME Noble, A Musacchio, M Saraste, SA Courtneidge, RK Wierenga
The EMBO journal 12 (7), 2617-2624, 1993
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3
N Macdonald, JPI Welburn, MEM Noble, A Nguyen, MB Yaffe, D Clynes, ...
Molecular cell 20 (2), 199-211, 2005
The structural basis for substrate recognition and control by protein kinases
LN Johnson, ED Lowe, MEM Noble, DJ Owen
FEBS letters 430 (1-2), 1-11, 1998
Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor
TG Davies, J Bentley, CE Arris, FT Boyle, NJ Curtin, JA Endicott, ...
Nature structural biology 9 (10), 745-749, 2002
The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition
ED Lowe, MEM Noble, VT Skamnaki, NG Oikonomakos, DJ Owen, ...
The EMBO journal, 1997
Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity
NR Brown, MEM Noble, AM Lawrie, MC Morris, P Tunnah, G Divita, ...
Journal of Biological Chemistry 274 (13), 8746-8756, 1999
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