| Fast prediction and visualization of protein binding pockets with PASS GP Brady, PFW Stouten Journal of computer-aided molecular design 14, 383-401, 2000 | 723 | 2000 |
| An effective solvation term based on atomic occupancies for use in protein simulations PFW Stouten, C Frömmel, H Nakamura, C Sander Molecular Simulation 10 (2-6), 97-120, 1993 | 370 | 1993 |
| A molecular mechanics/grid method for evaluation of ligand–receptor interactions BA Luty, ZR Wasserman, PFW Stouten, CN Hodge, M Zacharias, ... Journal of Computational Chemistry 16 (4), 454-464, 1995 | 292 | 1995 |
| Inhibition of protein–protein interactions: The discovery of druglike β‐catenin inhibitors by combining virtual and biophysical screening JY Trosset, C Dalvit, S Knapp, M Fasolini, M Veronesi, S Mantegani, ... Proteins: Structure, Function, and Bioinformatics 64 (1), 60-67, 2006 | 221 | 2006 |
| Influence of molecular flexibility and polar surface area metrics on oral bioavailability in the rat JJ Lu, K Crimin, JT Goodwin, P Crivori, C Orrenius, L Xing, PJ Tandler, ... Journal of medicinal chemistry 47 (24), 6104-6107, 2004 | 194 | 2004 |
| Assessment of docking poses: interactions-based accuracy classification (IBAC) versus crystal structure deviations RT Kroemer, A Vulpetti, JJ McDonald, DC Rohrer, JY Trosset, ... Journal of Chemical Information and Computer Sciences 44 (3), 871-881, 2004 | 150 | 2004 |
| Synthesis and Biological Evaluation of 1-Aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one Inhibitors of Cyclin-Dependent Kinases JA Markwalder, MR Arnone, PA Benfield, M Boisclair, CR Burton, ... Journal of medicinal chemistry 47 (24), 5894-5911, 2004 | 148 | 2004 |
| The design and application of target-focused compound libraries C John Harris, R D Hill, D W Sheppard, M J Slater, P FW Stouten Combinatorial chemistry & high throughput screening 14 (6), 521-531, 2011 | 146 | 2011 |
| Type II ‘to Type I β-Turn Swap Changes Specificity for Integrins AC Bach, JR Espina, SA Jackson, PFW Stouten, JL Duke, SA Mousa, ... Journal of the American Chemical Society 118 (1), 293-294, 1996 | 129 | 1996 |
| How does the switch II region of G‐domains work? PFW Stouten, C Sander, A Wittinghofer, A Valencia FEBS letters 320 (1), 1-6, 1993 | 107 | 1993 |
| New triple-helical model for the shaft of the adenovirus fibre PFW Stouten, C Sander, RWH Ruigrok, S Cusack Journal of molecular biology 226 (4), 1073-1084, 1992 | 106 | 1992 |
| Rational design and synthesis of novel, potent bis-phenylamidine carboxylate factor Xa inhibitors TP Maduskuie, KJ McNamara, Y Ru, RM Knabb, PFW Stouten Journal of medicinal chemistry 41 (1), 53-62, 1998 | 68 | 1998 |
| Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish S Camus, C Quevedo, S Menéndez, I Paramonov, PFW Stouten, ... Oncogene 31 (39), 4333-4342, 2012 | 61 | 2012 |
| Discovery of N-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-lH-pyrazole-5-carboxamide (GLPG1837), a Novel Potentiator Which … SE Van der Plas, H Kelgtermans, T De Munck, SLX Martina, S Dropsit, ... Journal of Medicinal Chemistry 61 (4), 1425-1435, 2018 | 60 | 2018 |
| A comparison of structural and dynamic properties of different simulation methods applied to SH3 DM van Aalten, A Amadei, R Bywater, JB Findlay, HJ Berendsen, ... Biophysical journal 70 (2), 684-692, 1996 | 56 | 1996 |
| Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors Q Han, C Dominguez, PFW Stouten, JM Park, DE Duffy, RA Galemmo, ... Journal of medicinal chemistry 43 (23), 4398-4415, 2000 | 53 | 2000 |
| Linear and nonlinear methods in modeling the aqueous solubility of organic compounds C Catana, H Gao, C Orrenius, PFW Stouten Journal of chemical information and modeling 45 (1), 170-176, 2005 | 51 | 2005 |
| Shedding light on important waters for drug design: simulations versus grid-based methods D Bucher, P Stouten, N Triballeau Journal of Chemical Information and Modeling 58 (3), 692-699, 2018 | 49 | 2018 |
| Docking and Scoring. Comprehensive Medicinal Chemistry II PFW Stouten, RT Kroemer Elsevier, 2007 | 42 | 2007 |
| Bisbenzamidine isoxazoline derivatives as factor Xa inhibitors ML Quan, JR Pruitt, CD Ellis, AY Liauw, RA Galemmo Jr, PFW Stouten, ... Bioorganic & Medicinal Chemistry Letters 7 (21), 2813-2818, 1997 | 41 | 1997 |
