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Ian F Harrison
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Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model
IF Harrison, O Ismail, A Machhada, N Colgan, Y Ohene, P Nahavandi, ...
Brain 143 (8), 2576-2593, 2020
3602020
Epigenetic targeting of histone deacetylase: therapeutic potential in Parkinson's disease?
IF Harrison, DT Dexter
Pharmacology & therapeutics 140 (1), 34-52, 2013
2542013
Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease
N Colgan, B Siow, JM O'Callaghan, IF Harrison, JA Wells, HE Holmes, ...
Neuroimage 125, 739-744, 2016
2332016
Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI
IF Harrison, B Siow, AB Akilo, PG Evans, O Ismail, Y Ohene, P Nahavandi, ...
Elife 7, e34028, 2018
1642018
Non-invasive MRI of brain clearance pathways using multiple echo time arterial spin labelling: an aquaporin-4 study
Y Ohene, IF Harrison, P Nahavandi, O Ismail, EV Bird, OP Ottersen, ...
Neuroimage 188, 515-523, 2019
1312019
Pathological histone acetylation in Parkinson’s disease: Neuroprotection and inhibition of microglial activation through SIRT 2 inhibition
IF Harrison, AD Smith, DT Dexter
Neuroscience letters 666, 48-57, 2018
1132018
Non-invasive MRI of blood–cerebrospinal fluid barrier function
PG Evans, M Sokolska, A Alves, IF Harrison, Y Ohene, P Nahavandi, ...
Nature communications 11 (1), 2081, 2020
942020
Prazosin, an α1-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease
L Katsouri, MP Vizcaychipi, S McArthur, I Harrison, M Suárez-Calvet, ...
Neurobiology of aging 34 (4), 1105-1115, 2013
812013
The Discovery of a Highly Selective 5,6,7,8‐Tetrahydrobenzo[4,5]thieno[2,3‐d]pyrimidin‐4(3H)‐one SIRT2 Inhibitor that is Neuroprotective in an in vitro Parkinson …
P Di Fruscia, E Zacharioudakis, C Liu, S Moniot, S Laohasinnarong, ...
ChemMedChem 10 (1), 69-82, 2015
802015
Impaired brain glymphatic flow in experimental hepatic encephalopathy
A Hadjihambi, IF Harrison, M Costas-Rodríguez, F Vanhaecke, N Arias, ...
Journal of hepatology 70 (1), 40-49, 2019
752019
Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease
J O'callaghan, H Holmes, N Powell, JA Wells, O Ismail, IF Harrison, ...
Neuroimage 159, 334-345, 2017
622017
An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson’s disease
IS Pienaar, IF Harrison, JL Elson, A Bury, P Woll, AK Simon, DT Dexter
Brain Structure and Function 220, 479-500, 2015
622015
Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of P arkinson's is associated with histone acetylation and up‐regulation of …
IF Harrison, WR Crum, AC Vernon, DT Dexter
British journal of pharmacology 172 (16), 4200-4215, 2015
582015
Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy
HE Holmes, NM Powell, D Ma, O Ismail, IF Harrison, JA Wells, N Colgan, ...
Frontiers in neuroinformatics 11, 20, 2017
542017
People with Parkinson’s disease: what symptoms do they most want to improve and how does this change with disease duration?
RJ Port, M Rumsby, G Brown, IF Harrison, A Amjad, CJ Bale
Journal of Parkinson's disease 11 (2), 715-724, 2021
532021
The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease
IF Harrison, NM Powell, DT Dexter
Journal of neurochemistry 148 (1), 136-156, 2019
522019
Imaging the accumulation and suppression of tau pathology using multiparametric MRI
HE Holmes, N Colgan, O Ismail, D Ma, NM Powell, JM O'Callaghan, ...
Neurobiology of aging 39, 184-194, 2016
482016
Propagation of tau and α-synuclein in the brain: therapeutic potential of the glymphatic system
DM Lopes, SK Llewellyn, IF Harrison
Translational Neurodegeneration 11 (1), 19, 2022
352022
Increased blood–brain barrier permeability to water in the aging brain detected using noninvasive multi‐TE ASL MRI
Y Ohene, IF Harrison, PG Evans, DL Thomas, MF Lythgoe, JA Wells
Magnetic resonance in medicine 85 (1), 326-333, 2021
302021
L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils
A Migdalska‐Richards, M Wegrzynowicz, IF Harrison, G Verona, V Bellotti, ...
PLoS One 15 (8), e0238075, 2020
302020
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Articles 1–20