Prof Gregory L Challis
Prof Gregory L Challis
Dept of Chemistry, Univ of Warwick; Dept of Biochemistry and Molecular Biology, Monash Univ
Patvirtintas el. paštas - Pagrindinis puslapis
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
SD Bentley, KF Chater, AM Cerdeño-Tárraga, GL Challis, NR Thomson, ...
nature 417 (6885), 141-147, 2002
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ...
Natural product reports 30 (1), 108-160, 2013
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
B Gust, GL Challis, K Fowler, T Kieser, KF Chater
Proceedings of the National Academy of Sciences 100 (4), 1541-1546, 2003
Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains
GL Challis, J Ravel, CA Townsend
Chemistry & biology 7 (3), 211-224, 2000
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei
MTG Holden, RW Titball, SJ Peacock, AM Cerdeño-Tárraga, T Atkins, ...
Proceedings of the National Academy of Sciences 101 (39), 14240-14245, 2004
Discovery of microbial natural products by activation of silent biosynthetic gene clusters
PJ Rutledge, GL Challis
Nature reviews microbiology 13 (8), 509-523, 2015
Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species
GL Challis, DA Hopwood
Proceedings of the National Academy of Sciences 100 (suppl_2), 14555-14561, 2003
Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens
MW Silby, AM Cerdeño-Tárraga, GS Vernikos, SR Giddens, RW Jackson, ...
Genome biology 10, 1-16, 2009
Discovery of a new peptide natural product by Streptomyces coelicolor genome mining
S Lautru, RJ Deeth, LM Bailey, GL Challis
Nature chemical biology 1 (5), 265-269, 2005
Strategies for the discovery of new natural products by genome mining
M Zerikly, GL Challis
ChemBioChem 10 (4), 625-633, 2009
A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases
GL Challis
Chembiochem 6 (4), 601-611, 2005
Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
L Laureti, L Song, S Huang, C Corre, P Leblond, GL Challis, B Aigle
Proceedings of the National Academy of Sciences 108 (15), 6258-6263, 2011
Mining microbial genomes for new natural products and biosynthetic pathways
GL Challis
Microbiology 154 (6), 1555-1569, 2008
Identification of a Cluster of Genes that Directs Desferrioxamine Biosynthesis in Streptomyces c oelicolor M145
F Barona-Gómez, U Wong, AE Giannakopulos, PJ Derrick, GL Challis
Journal of the American Chemical Society 126 (50), 16282-16283, 2004
Genome mining for novel natural product discovery
GL Challis
Journal of medicinal chemistry 51 (9), 2618-2628, 2008
The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081
NR Thomson, S Howard, BW Wren, MTG Holden, L Crossman, GL Challis, ...
PLoS genetics 2 (12), e206, 2006
Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide …
GL Challis, J Ravel
FEMS microbiology letters 187 (2), 111-114, 2000
Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3 (2): new mechanisms for chain initiation and termination in modular multienzymes
AM Cerdeño, MJ Bibb, GL Challis
Chemistry & biology 8 (8), 817-829, 2001
Mechanism and catalytic diversity of Rieske non-heme iron-dependent oxygenases
SM Barry, GL Challis
ACS catalysis 3 (10), 2362-2370, 2013
Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis
SM Barry, JA Kers, EG Johnson, L Song, PR Aston, B Patel, SB Krasnoff, ...
Nature chemical biology 8 (10), 814-816, 2012
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Straipsniai 1–20