| Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2) SD Bentley, KF Chater, AM Cerdeño-Tárraga, GL Challis, NR Thomson, ... nature 417 (6885), 141-147, 2002 | 4342 | 2002 |
| Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ... Natural product reports 30 (1), 108-160, 2013 | 2185 | 2013 |
| PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin B Gust, GL Challis, K Fowler, T Kieser, KF Chater Proceedings of the National Academy of Sciences 100 (4), 1541-1546, 2003 | 1727 | 2003 |
| Discovery of microbial natural products by activation of silent biosynthetic gene clusters PJ Rutledge, GL Challis Nature reviews microbiology 13 (8), 509-523, 2015 | 1030 | 2015 |
| Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains GL Challis, J Ravel, CA Townsend Chemistry & biology 7 (3), 211-224, 2000 | 1000 | 2000 |
| Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei MTG Holden, RW Titball, SJ Peacock, AM Cerdeño-Tárraga, T Atkins, ... Proceedings of the National Academy of Sciences 101 (39), 14240-14245, 2004 | 948 | 2004 |
| Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species GL Challis, DA Hopwood Proceedings of the National Academy of Sciences 100 (suppl_2), 14555-14561, 2003 | 877 | 2003 |
| Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens MW Silby, AM Cerdeño-Tárraga, GS Vernikos, SR Giddens, RW Jackson, ... Genome biology 10, 1-16, 2009 | 490 | 2009 |
| Discovery of a new peptide natural product by Streptomyces coelicolor genome mining S Lautru, RJ Deeth, LM Bailey, GL Challis Nature chemical biology 1 (5), 265-269, 2005 | 485 | 2005 |
| Strategies for the discovery of new natural products by genome mining M Zerikly, GL Challis ChemBioChem 10 (4), 625-633, 2009 | 419 | 2009 |
| Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens L Laureti, L Song, S Huang, C Corre, P Leblond, GL Challis, B Aigle Proceedings of the National Academy of Sciences 108 (15), 6258-6263, 2011 | 411 | 2011 |
| A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases GL Challis Chembiochem 6 (4), 601-611, 2005 | 406 | 2005 |
| Mining microbial genomes for new natural products and biosynthetic pathways GL Challis Microbiology 154 (6), 1555-1569, 2008 | 338 | 2008 |
| Identification of a Cluster of Genes that Directs Desferrioxamine Biosynthesis in Streptomyces c oelicolor M145 F Barona-Gómez, U Wong, AE Giannakopulos, PJ Derrick, GL Challis Journal of the American Chemical Society 126 (50), 16282-16283, 2004 | 301 | 2004 |
| Genome mining for novel natural product discovery GL Challis Journal of medicinal chemistry 51 (9), 2618-2628, 2008 | 299 | 2008 |
| Coelichelin, a new peptide siderophore encoded by the Streptomyces coelicolor genome: structure prediction from the sequence of its non-ribosomal peptide
GL Challis, J Ravel FEMS microbiology letters 187 (2), 111-114, 2000 | 276 | 2000 |
| The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081 NR Thomson, S Howard, BW Wren, MTG Holden, L Crossman, GL Challis, ... PLoS genetics 2 (12), e206, 2006 | 272 | 2006 |
| Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3 (2): new mechanisms for chain initiation and termination in modular multienzymes AM Cerdeño, MJ Bibb, GL Challis Chemistry & biology 8 (8), 817-829, 2001 | 265 | 2001 |
| Mechanism and catalytic diversity of Rieske non-heme iron-dependent oxygenases SM Barry, GL Challis ACS catalysis 3 (10), 2362-2370, 2013 | 264 | 2013 |
| Cytochrome P450catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis SM Barry, JA Kers, EG Johnson, L Song, PR Aston, B Patel, SB Krasnoff, ... Nature chemical biology 8 (10), 814-816, 2012 | 231 | 2012 |
