Jiekai Chen
Jiekai Chen
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
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A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
R Li, J Liang, S Ni, T Zhou, X Qing, H Li, W He, J Chen, F Li, Q Zhuang, ...
Cell stem cell 7 (1), 51-63, 2010
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
MA Esteban, T Wang, B Qin, J Yang, D Qin, J Cai, W Li, Z Weng, J Chen, ...
Cell stem cell 6 (1), 71-79, 2010
Generation of induced pluripotent stem cell lines from Tibetan miniature pig
MA Esteban, J Xu, J Yang, M Peng, D Qin, W Li, Z Jiang, J Chen, K Deng, ...
Journal of Biological Chemistry 284 (26), 17634-17640, 2009
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs
J Chen, H Liu, J Liu, J Qi, B Wei, J Yang, H Liang, Y Chen, J Chen, Y Wu, ...
Nature genetics 45 (1), 34-42, 2013
COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas
X Ren, W Wen, X Fan, W Hou, B Su, P Cai, J Li, Y Liu, F Tang, F Zhang, ...
Cell 184 (7), 1895-1913. e19, 2021
Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment
J Sun, Z Zhuang, J Zheng, K Li, RLY Wong, D Liu, J Huang, J He, A Zhu, ...
Cell 182 (3), 734-743. e5, 2020
Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming
X Hu, L Zhang, SQ Mao, Z Li, J Chen, RR Zhang, HP Wu, J Gao, F Guo, ...
Cell stem cell 14 (4), 512-522, 2014
Vitamin C modulates TET1 function during somatic cell reprogramming
J Chen, L Guo, L Zhang, H Wu, J Yang, H Liu, X Wang, X Hu, T Gu, ...
Nature genetics 45 (12), 1504-1509, 2013
Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT–MET mechanism for optimal reprogramming
X Liu, H Sun, J Qi, L Wang, S He, J Liu, C Feng, C Chen, W Li, Y Guo, ...
Nature cell biology 15 (7), 829-838, 2013
Rapamycin and other longevity‐promoting compounds enhance the generation of mouse induced pluripotent stem cells
T Chen, L Shen, J Yu, H Wan, A Guo, J Chen, Y Long, J Zhao, G Pei
Aging cell 10 (5), 908-911, 2011
Chromatin accessibility dynamics during iPSC reprogramming
D Li, J Liu, X Yang, C Zhou, J Guo, C Wu, Y Qin, L Guo, J He, S Yu, H Liu, ...
Cell stem cell 21 (6), 819-833. e6, 2017
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
X Bao, H Wu, X Zhu, X Guo, AP Hutchins, Z Luo, H Song, Y Chen, K Lai, ...
Cell research 25 (1), 80-92, 2015
BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone
J Chen, J Liu, J Yang, Y Chen, J Chen, S Ni, H Song, L Zeng, K Ding, ...
Cell research 21 (1), 205-212, 2011
The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity
J Liu, M Gao, J He, K Wu, S Lin, L Jin, Y Chen, H Liu, J Shi, X Wang, ...
Nature 591 (7849), 322-326, 2021
Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells
Q Wang, X Xu, J Li, J Liu, H Gu, R Zhang, J Chen, Y Kuang, J Fei, C Jiang, ...
Cell research 21 (10), 1424-1435, 2011
The oncogene c-Jun impedes somatic cell reprogramming
J Liu, Q Han, T Peng, M Peng, B Wei, D Li, X Wang, S Yu, J Yang, S Cao, ...
Nature cell biology 17 (7), 856-867, 2015
Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells
J He, X Fu, M Zhang, F He, W Li, MM Abdul, J Zhou, L Sun, C Chang, Y Li, ...
Nature Communications 10 (1), 34, 2019
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
B Xia, X Shen, Y He, X Pan, FL Liu, Y Wang, F Yang, S Fang, Y Wu, ...
Cell research 31 (8), 847-860, 2021
Reprogramming of mouse and human somatic cells by high‐performance engineered factors
Y Wang, J Chen, JL Hu, XX Wei, D Qin, J Gao, L Zhang, J Jiang, JS Li, ...
EMBO reports 12 (4), 373-378, 2011
Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics
J Chen, J Liu, Y Chen, J Yang, J Chen, H Liu, X Zhao, K Mo, H Song, ...
Cell research 21 (6), 884-894, 2011
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