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LH Tsai
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Integrative analysis of 111 reference human epigenomes
A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ...
Nature 518 (7539), 317-330, 2015
59482015
Driving fast-spiking cells induces gamma rhythm and controls sensory responses
JA Cardin, M Carlén, K Meletis, U Knoblich, F Zhang, K Deisseroth, ...
Nature 459 (7247), 663-667, 2009
27982009
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
GN Patrick, L Zukerberg, M Nikolic, S de La Monte, P Dikkes, LH Tsai
Nature 402 (6762), 615-622, 1999
18881999
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kip1-deficient mice
ML Fero, M Rivkin, M Tasch, P Porter, CE Carow, E Firpo, K Polyak, ...
Cell 85 (5), 733-744, 1996
18271996
HDAC2 negatively regulates memory formation and synaptic plasticity
JS Guan, SJ Haggarty, E Giacometti, JH Dannenberg, N Joseph, J Gao, ...
Nature 459 (7243), 55-60, 2009
17522009
Single-cell transcriptomic analysis of Alzheimer’s disease
H Mathys, J Davila-Velderrain, Z Peng, F Gao, S Mohammadi, JZ Young, ...
Nature 570 (7761), 332-337, 2019
17092019
Recovery of learning and memory is associated with chromatin remodelling
A Fischer, F Sananbenesi, X Wang, M Dobbin, LH Tsai
Nature 447 (7141), 178-182, 2007
14242007
A decade of CDK5
R Dhavan, LH Tsai
Nature reviews Molecular cell biology 2 (10), 749-759, 2001
13792001
Inhibition of cyclin-dependent kinases by p21.
JW Harper, SJ Elledge, K Keyomarsi, B Dynlacht, LH Tsai, P Zhang, ...
Molecular biology of the cell 6 (4), 387-400, 1995
13761995
Neurotoxicity induces cleavage of p35 to p25 by calpain
M Lee, YT Kwon, M Li, J Peng, RM Friedlander, LH Tsai
Nature 405 (6784), 360-364, 2000
13152000
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
D Kim, MD Nguyen, MM Dobbin, A Fischer, F Sananbenesi, JT Rodgers, ...
The EMBO journal 26 (13), 3169-3179, 2007
12562007
A family of human cdc2‐related protein kinases.
M Meyerson, GH Enders, CL Wu, LK Su, C Gorka, C Nelson, E Harlow, ...
The EMBO journal 11 (8), 2909-2917, 1992
11741992
p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
LH Tsai, I Delalle, VS Caviness Jr, T Chae, E Harlow
Nature 371 (6496), 419-423, 1994
11161994
A novel pathway regulates memory and plasticity via SIRT1 and miR-134
J Gao, WY Wang, YW Mao, J Gräff, JS Guan, L Pan, G Mak, D Kim, SC Su, ...
Nature 466 (7310), 1105-1109, 2010
10862010
Gamma frequency entrainment attenuates amyloid load and modifies microglia
HF Iaccarino, AC Singer, AJ Martorell, A Rudenko, F Gao, TZ Gillingham, ...
Nature 540 (7632), 230-235, 2016
10552016
Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality
T Chae, YT Kwon, R Bronson, P Dikkes, E Li, LH Tsai
Neuron 18 (1), 29-42, 1997
9061997
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3β/β-catenin signaling
Y Mao, X Ge, CL Frank, JM Madison, AN Koehler, MK Doud, C Tassa, ...
Cell 136 (6), 1017-1031, 2009
8982009
An epigenetic blockade of cognitive functions in the neurodegenerating brain
J Gräff, D Rei, JS Guan, WY Wang, J Seo, KM Hennig, TJF Nieland, ...
Nature 483 (7388), 222-226, 2012
8862012
APOE4 causes widespread molecular and cellular alterations associated with Alzheimer’s disease phenotypes in human iPSC-derived brain cell types
YT Lin, J Seo, F Gao, HM Feldman, HL Wen, J Penney, HP Cam, ...
Neuron 98 (6), 1141-1154. e7, 2018
8782018
The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.
M Nikolic, H Dudek, YT Kwon, YF Ramos, LH Tsai
Genes & development 10 (7), 816-825, 1996
7281996
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