Irantzu Pallarès
Irantzu Pallarès
Professora Titular de Bioquímica
Patvirtintas el. paštas
Amyloid fibril formation by a partially structured intermediate state of α-chymotrypsin
I Pallarès, J Vendrell, FX Avilés, S Ventura
Journal of molecular biology 342 (1), 321-331, 2004
Prediction of" hot spots" of aggregation in disease-linked polypeptides
NS De Groot, I Pallarés, FX Avilés, J Vendrell, S Ventura
BMC Structural Biology 5, 1-15, 2005
Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity
R Sant'Anna, P Gallego, LZ Robinson, A Pereira-Henriques, N Ferreira, ...
Nature communications 7 (1), 10787, 2016
Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin
I Pallarès, R Bonet, R García-Castellanos, S Ventura, FX Avilés, ...
Proceedings of the National Academy of Sciences 102 (11), 3978-3983, 2005
Dissecting the contribution of Staphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure
P Marinelli, I Pallares, S Navarro, S Ventura
Scientific reports 6 (1), 1-13, 2016
Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis
L Sanglas, Z Valnickova, JL Arolas, I Pallarés, T Guevara, M Solà, ...
Molecular cell 31 (4), 598-606, 2008
Progress in metallocarboxypeptidases and their small molecular weight inhibitors
D Fernández, I Pallarès, J Vendrell, FX Avilés
Biochimie 92 (11), 1484-1500, 2010
The Crystal Structure of Thrombin-activable Fibrinolysis Inhibitor (TAFI) Provides the Structural Basis for Its Intrinsic Activity and the Short Half-life of TAFIa∗♦
K Anand, I Pallares, Z Valnickova, T Christensen, J Vendrell, KU Wendt, ...
Journal of Biological Chemistry 283 (43), 29416-29423, 2008
pH-dependent aggregation in intrinsically disordered proteins is determined by charge and lipophilicity
J Santos, V Iglesias, J Santos-Suárez, M Mangiagalli, S Brocca, I Pallarès, ...
Cells 9 (1), 145, 2020
Chemical chaperones as novel drugs for Parkinson’s disease
J Pujols, S Peña-Díaz, I Pallarès, S Ventura
Trends in Molecular Medicine 26 (4), 408-421, 2020
Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications
J Santos, J Pujols, I Pallarès, V Iglesias, S Ventura
Computational and structural biotechnology journal 18, 1403-1413, 2020
Discovering Putative Prion-Like Proteins in Plasmodium falciparum: A Computational and Experimental Analysis
I Pallarès, NS De Groot, V Iglesias, R Sant’Anna, A Biosca, ...
Frontiers in microbiology 9, 1737, 2018
The Rho Termination Factor of Clostridium botulinum Contains a Prion-Like Domain with a Highly Amyloidogenic Core
I Pallarès, V Iglesias, S Ventura
Frontiers in microbiology 6, 1516, 2016
α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity
J Santos, P Gracia, S Navarro, S Peña-Díaz, J Pujols, N Cremades, ...
Nature communications 12 (1), 3752, 2021
Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis
F Pinheiro, N Varejão, S Esperante, J Santos, A Velázquez‐Campoy, ...
The FEBS Journal 288 (1), 310-324, 2021
Understanding and predicting protein misfolding and aggregation: Insights from proteomics
I Pallarès, S Ventura
Proteomics 16 (19), 2570-2581, 2016
Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin
R Garcia-Castellanos, R Bonet-Figueredo, I Pallares, S Ventura, ...
Cellular and Molecular Life Sciences CMLS 62, 1996-2014, 2005
A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus
D Fernández, S Russi, J Vendrell, M Monod, I Pallares
Acta Crystallographica Section D: Biological Crystallography 69 (10), 1946-1957, 2013
Advances in the prediction of protein aggregation propensity
I Pallarès, S Ventura
Current Medicinal Chemistry 26 (21), 3911-3920, 2019
Metallocarboxypeptidases and their inhibitors: Recent developments in biomedically relevant protein and organic ligands
D Fernández, I Pallarès, G Covaleda, F X Aviles, J Vendrell
Current Medicinal Chemistry 20 (12), 1595-1608, 2013
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Straipsniai 1–20