Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer ND Kim, R Mehta, W Yu, I Neeman, T Livney, A Amichay, D Poirier, ... Breast cancer research and treatment 71 (3), 203-217, 2002 | 733 | 2002 |
Inhibitors of 17β-hydroxysteroid dehydrogenases D Poirier Current medicinal chemistry 10 (6), 453-477, 2003 | 260 | 2003 |
Comparison between hippocampus-synthesized and circulation-derived sex steroids in the hippocampus Y Hojo, S Higo, H Ishii, Y Ooishi, H Mukai, G Murakami, T Kominami, ... Endocrinology 150 (11), 5106-5112, 2009 | 182 | 2009 |
Characteristics of human types 1, 2 and 3 17β-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition V Luu-The, Y Zhang, D Poirier, F Labrie The Journal of steroid biochemistry and molecular biology 55 (5), 581-587, 1995 | 177 | 1995 |
Metal-based biologically active agents: Synthesis, characterization, antibacterial and antileukemia activity evaluation of Cu (II), V (IV) and Ni (II) complexes with antipyrine … T Rosu, M Negoiu, S Pasculescu, E Pahontu, D Poirier, A Gulea European journal of medicinal chemistry 45 (2), 774-781, 2010 | 176 | 2010 |
Synthesis and characterization of some new Cu (II), Ni (II) and Zn (II) complexes with salicylidene thiosemicarbazones: antibacterial, antifungal and in vitro antileukemia activity E Pahontu, V Fala, A Gulea, D Poirier, V Tapcov, T Rosu Molecules 18 (8), 8812-8836, 2013 | 155 | 2013 |
Molecular therapy of breast cancer: progress and future directions SX Lin, J Chen, M Mazumdar, D Poirier, C Wang, A Azzi, M Zhou Nature Reviews Endocrinology 6 (9), 485-493, 2010 | 152 | 2010 |
17β-Hydroxysteroid dehydrogenase inhibitors: a patent review D Poirier Expert opinion on therapeutic patents 20 (9), 1123-1145, 2010 | 122 | 2010 |
A concerted, rational design of type 1 17β-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity W Qiu, RL Campbell, A Gangloff, P Dupuis, RP Boivin, MR Tremblay, ... The FASEB Journal 16 (13), 1829-1831, 2002 | 114 | 2002 |
Overview of a rational approach to design type I 17β-hydroxysteroid dehydrogenase inhibitors without estrogenic activity: chemical synthesis and biological … MR Tremblay, D Poirier The Journal of steroid biochemistry and molecular biology 66 (4), 179-191, 1998 | 102 | 1998 |
In vitro antileukemia, antibacterial and antifungal activities of some 3d metal complexes: Chemical synthesis and structure – activity relationships A Gulea, D Poirier, J Roy, V Stavila, I Bulimestru, V Tapcov, M Birca, ... Journal of enzyme inhibition and medicinal chemistry 23 (6), 806-818, 2008 | 101 | 2008 |
Structure− Activity Relationships of 17α-Derivatives of Estradiol as Inhibitors of Steroid Sulfatase RP Boivin, V Luu-The, R Lachance, F Labrie, D Poirier Journal of medicinal chemistry 43 (23), 4465-4478, 2000 | 101 | 2000 |
17β-hydroxysteroid dehydrogenase Type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production JA Aka, M Mazumdar, CQ Chen, D Poirier, SX Lin Molecular endocrinology 24 (4), 832-845, 2010 | 100 | 2010 |
Estradiol and estrone C-16 derivatives as inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Blocking of ER+ breast cancer cell proliferation induced by estrone Y Laplante, C Cadot, MA Fournier, D Poirier Bioorganic & medicinal chemistry 16 (4), 1849-1860, 2008 | 98 | 2008 |
Antiestrogenic properties of keoxifene,trans-4-hydroxytamoxifen, and ICI 164384, a new steroidal antiestrogen, in ZR-75-1 human breast cancer cells R Poulin, Y Merand, D Poirier, C Levesque, JM Dufour, F Labrie Breast cancer research and treatment 14 (1), 65-76, 1989 | 98 | 1989 |
Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells R Poulin, D Baker, D Poirier, F Labrie Breast cancer research and treatment 13 (2), 161-172, 1989 | 98 | 1989 |
Binary and ternary crystal structure analyses of a novel inhibitor with 17β-HSD type 1: a lead compound for breast cancer therapy M Mazumdar, D Fournier, DW Zhu, C Cadot, D Poirier, SX Lin Biochemical Journal 424 (3), 357-366, 2009 | 93 | 2009 |
Blockade of the stimulatory effect of estrogens, OH-tamoxifen, OH-toremifene, droloxifene, and raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human … J Simard, R Sanchez, D Poirier, S Gauthier, SM Singh, Y Merand, ... Cancer research 57 (16), 3494-3497, 1997 | 93 | 1997 |
Steroid sulfatase inhibitors: a review covering the promising 2000–2010 decade R Maltais, D Poirier Steroids 76 (10), 929-948, 2011 | 90 | 2011 |
Multiple actions of synthetic ‘progestins’ on the growth of ZR-75-1 human breast cancer cells: Anin vitro model for the simultaneous assay of androgen, progestin … R Poulin, D Baker, D Poirier, F Labrie Breast cancer research and treatment 17 (3), 197-210, 1991 | 89 | 1991 |