Millisecond-timescale, genetically targeted optical control of neural activity ES Boyden, F Zhang, E Bamberg, G Nagel, K Deisseroth Nature neuroscience 8 (9), 1263-1268, 2005 | 6009 | 2005 |
Independent optical excitation of distinct neural populations NC Klapoetke, Y Murata, SS Kim, SR Pulver, A Birdsey-Benson, YK Cho, ... Nature methods 11 (3), 338-346, 2014 | 2382 | 2014 |
Maneuverable surgical stapler ES Boyden, RA Hyde, MY Ishikawa, EC Leuthardt, NP Myhrvold, DJ Rivet, ... US Patent 8,172,120, 2012 | 1822 | 2012 |
Expansion microscopy F Chen, PW Tillberg, ES Boyden Science 347 (6221), 543-548, 2015 | 1529 | 2015 |
High-performance genetically targetable optical neural silencing by light-driven proton pumps BY Chow, X Han, AS Dobry, X Qian, AS Chuong, M Li, MA Henninger, ... Nature 463 (7277), 98-102, 2010 | 1475 | 2010 |
A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing L Madisen, T Mao, H Koch, J Zhuo, A Berenyi, S Fujisawa, YWA Hsu, ... Nature neuroscience 15 (5), 793-802, 2012 | 1378 | 2012 |
Gamma frequency entrainment attenuates amyloid load and modifies microglia HF Iaccarino, AC Singer, AJ Martorell, A Rudenko, F Gao, TZ Gillingham, ... Nature 540 (7632), 230-235, 2016 | 1194 | 2016 |
Cell diversity and network dynamics in photosensitive human brain organoids G Quadrato, T Nguyen, EZ Macosko, JL Sherwood, S Min Yang, ... Nature 545 (7652), 48-53, 2017 | 1182 | 2017 |
Active tremor control in surgical instruments ES Boyden, GJ Della Rocca, RA Hyde, R Langer, EC Leuthardt, ... US Patent App. 13/857,038, 2014 | 1175 | 2014 |
Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance L Madisen, AR Garner, D Shimaoka, AS Chuong, NC Klapoetke, L Li, ... Neuron 85 (5), 942-958, 2015 | 1074 | 2015 |
Channelrhodopsin-2 and optical control of excitable cells F Zhang, LP Wang, ES Boyden, K Deisseroth Nature methods 3 (10), 785-792, 2006 | 946 | 2006 |
Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy R Prevedel, YG Yoon, M Hoffmann, N Pak, G Wetzstein, S Kato, ... Nature methods 11 (7), 727-730, 2014 | 885 | 2014 |
Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution X Han, ES Boyden PloS one 2 (3), e299, 2007 | 885 | 2007 |
All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins DR Hochbaum, Y Zhao, SL Farhi, N Klapoetke, CA Werley, V Kapoor, ... Nature methods 11 (8), 825-833, 2014 | 836 | 2014 |
Noninvasive deep brain stimulation via temporally interfering electric fields N Grossman, D Bono, N Dedic, SB Kodandaramaiah, A Rudenko, HJ Suk, ... cell 169 (6), 1029-1041. e16, 2017 | 781 | 2017 |
A suite of transgenic driver and reporter mouse lines with enhanced brain-cell-type targeting and functionality TL Daigle, L Madisen, TA Hage, MT Valley, U Knoblich, RS Larsen, ... Cell 174 (2), 465-480. e22, 2018 | 711 | 2018 |
Activation of specific interneurons improves V1 feature selectivity and visual perception SH Lee, AC Kwan, S Zhang, V Phoumthipphavong, JG Flannery, ... Nature 488 (7411), 379-383, 2012 | 663 | 2012 |
A jump-start for electroceuticals K Famm, B Litt, KJ Tracey, ES Boyden, M Slaoui Nature 496 (7444), 159-161, 2013 | 654 | 2013 |
Noninvasive optical inhibition with a red-shifted microbial rhodopsin AS Chuong, ML Miri, V Busskamp, GAC Matthews, LC Acker, ... Nature neuroscience 17 (8), 1123-1129, 2014 | 629 | 2014 |
A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex X Han, BY Chow, H Zhou, NC Klapoetke, A Chuong, R Rajimehr, A Yang, ... Frontiers in systems neuroscience 5, 18, 2011 | 629 | 2011 |