Sava Sakadzic
Sava Sakadzic
Massachusetts General Hospital, Harvard Medical School
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Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue
S Sakadžić, E Roussakis, MA Yaseen, ET Mandeville, VJ Srinivasan, ...
Nature methods 7 (9), 755-759, 2010
Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain
K Kisler, AR Nelson, SV Rege, A Ramanathan, Y Wang, A Ahuja, D Lazic, ...
Nature neuroscience 20 (3), 406-416, 2017
Quantitative cerebral blood flow with optical coherence tomography
VJ Srinivasan, S Sakadžić, I Gorczynska, S Ruvinskaya, W Wu, ...
Optics express 18 (3), 2477-2494, 2010
In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase
K Nizar, H Uhlirova, P Tian, PA Saisan, Q Cheng, L Reznichenko, ...
Journal of Neuroscience 33 (19), 8411-8422, 2013
Quantifying the microvascular origin of BOLD-fMRI from first principles with two-photon microscopy and an oxygen-sensitive nanoprobe
L Gagnon, S Sakadžić, F Lesage, JJ Musacchia, J Lefebvre, Q Fang, ...
Journal of Neuroscience 35 (8), 3663-3675, 2015
Dendritic phosphorescent probes for oxygen imaging in biological systems
AY Lebedev, AV Cheprakov, S Sakadzic, DA Boas, DF Wilson, ...
ACS applied materials & interfaces 1 (6), 1292-1304, 2009
Cell type specificity of neurovascular coupling in cerebral cortex
H Uhlirova, K Kılıç, P Tian, M Thunemann, M Desjardins, PA Saisan, ...
elife 5, e14315, 2016
“Overshoot” of O2 is required to maintain baseline tissue oxygenation at locations distal to blood vessels
A Devor, S Sakadžić, PA Saisan, MA Yaseen, E Roussakis, VJ Srinivasan, ...
Journal of Neuroscience 31 (38), 13676-13681, 2011
Frontiers in optical imaging of cerebral blood flow and metabolism
A Devor, S Sakadžić, VJ Srinivasan, MA Yaseen, K Nizar, PA Saisan, ...
Journal of Cerebral Blood Flow & Metabolism 32 (7), 1259-1276, 2012
Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue
S Sakadžić, ET Mandeville, L Gagnon, JJ Musacchia, MA Yaseen, ...
Nature communications 5 (1), 5734, 2014
Supply-demand mismatch transients in susceptible peri-infarct hot zones explain the origins of spreading injury depolarizations
D von Bornstädt, T Houben, JL Seidel, Y Zheng, E Dilekoz, T Qin, ...
Neuron 85 (5), 1117-1131, 2015
Establishing the diffuse correlation spectroscopy signal relationship with blood flow
DA Boas, S Sakadžić, J Selb, P Farzam, MA Franceschini, SA Carp
Neurophotonics 3 (3), 031412-031412, 2016
High-resolution ultrasound-modulated optical tomography in biological tissues
S Sakadžić, LV Wang
Optics letters 29 (23), 2770-2772, 2004
Oxygen advection and diffusion in a three-dimensional vascular anatomical network
Q Fang, S Sakadžić, L Ruvinskaya, A Devor, AM Dale, DA Boas
Optics express 16 (22), 17530-17541, 2008
Potential circadian effects on translational failure for neuroprotection
E Esposito, W Li, E T. Mandeville, JH Park, I Şencan, S Guo, J Shi, J Lan, ...
Nature 582 (7812), 395-398, 2020
In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH
MA Yaseen, S Sakadžić, W Wu, W Becker, KA Kasischke, DA Boas
Biomedical optics express 4 (2), 307-321, 2013
Polarization sensitive optical coherence microscopy for brain imaging
H Wang, T Akkin, C Magnain, R Wang, J Dubb, WJ Kostis, MA Yaseen, ...
Optics letters 41 (10), 2213-2216, 2016
Benchmark calculations for Monte Carlo simulations of electron transport
ZM Raspopovic, S Sakadzic, SA Bzenic, ZL Petrovic
IEEE transactions on plasma science 27 (5), 1241-1248, 1999
Dendritic upconverting nanoparticles enable in vivo multiphoton microscopy with low-power continuous wave sources
TV Esipova, X Ye, JE Collins, S Sakadžić, ET Mandeville, CB Murray, ...
Proceedings of the National Academy of Sciences 109 (51), 20826-20831, 2012
Multiparametric, longitudinal optical coherence tomography imaging reveals acute injury and chronic recovery in experimental ischemic stroke
VJ Srinivasan, ET Mandeville, A Can, F Blasi, M Climov, A Daneshmand, ...
PloS one 8 (8), e71478, 2013
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