Prodrug approaches to improving the oral absorption of antiviral nucleotide analogues LW Peterson, CE McKenna Expert Opinion on Drug Delivery 6 (4), 405-420, 2009 | 72 | 2009 |
Encoding phenotype in bacteria with an alternative genetic set AT Krueger, LW Peterson, J Chelliserry, DJ Kleinbaum, ET Kool Journal of the American Chemical Society 133 (45), 18447-18451, 2011 | 69 | 2011 |
Degradable hybrid materials based on cationic acylhydrazone dynamic covalent polymers promote DNA complexation through multivalent interactions C Bouillon, D Paolantoni, JC Rote, Y Bessin, LW Peterson, P Dumy, ... Chemistry–A European Journal 20 (45), 14705-14714, 2014 | 55 | 2014 |
Serine peptide phosphoester prodrugs of cyclic cidofovir: synthesis, transport, and antiviral activity U Eriksson, LW Peterson, BA Kashemirov, JM Hilfinger, JC Drach, ... Molecular pharmaceutics 5 (4), 598-609, 2008 | 54 | 2008 |
Tyrosine-Based 1-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) Prodrugs: Synthesis, Stability, Antiviral … VM Zakharova, M Serpi, IS Krylov, LW Peterson, JM Breitenbach, ... Journal of medicinal chemistry 54 (16), 5680-5693, 2011 | 50 | 2011 |
Modifications to the dNTP triphosphate moiety: From mechanistic probes for DNA polymerases to antiviral and anti-cancer drug design CE McKenna, BA Kashemirov, LW Peterson, MF Goodman Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (5), 1223-1230, 2010 | 38 | 2010 |
Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1 LW Peterson, M Sala-Rabanal, IS Krylov, M Serpi, BA Kashemirov, ... Molecular pharmaceutics 7 (6), 2349-2361, 2010 | 31 | 2010 |
Steric restrictions of RISC in RNA interference identified with size-expanded RNA nucleobases AR Hernández, LW Peterson, ET Kool ACS chemical biology 7 (8), 1454-1461, 2012 | 30 | 2012 |
Effects of implicit solvent and relaxed amino acid side chains on the MP2 and DFT calculations of ligand–protein structure and electronic interaction energies of dopaminergic … DJ Bigler, LW Peterson, M Cafiero Computational and Theoretical Chemistry 1051, 79-92, 2015 | 21 | 2015 |
Synthesis, transport and antiviral activity of Ala–Ser and Val–Ser prodrugs of cidofovir LW Peterson, JS Kim, P Kijek, S Mitchell, J Hilfinger, J Breitenbach, ... Bioorganic & medicinal chemistry letters 21 (13), 4045-4049, 2011 | 20 | 2011 |
Catechol reactivity: Synthesis of dopamine derivatives substituted at the 6-position JC Rote, SN Malkowski, CS Cochrane, GE Bailey, NS Brown, M Cafiero, ... Synthetic Communications 47 (5), 435-441, 2017 | 14 | 2017 |
Ab initio study of electronic interaction energies and desolvation energies for dopaminergic ligands in the catechol-O-methyltransferase active site AK Hatstat, M Morris, LW Peterson, M Cafiero Computational and Theoretical Chemistry 1078, 146-162, 2016 | 14 | 2016 |
Design, modeling and synthesis of 1, 2, 3-triazole-linked nucleoside-amino acid conjugates as potential antibacterial agents SN Malkowski, CF Dishuck, GG Lamanilao, CP Embry, CS Grubb, ... Molecules 22 (10), 1682, 2017 | 13 | 2017 |
Puromycin-sensitive aminopeptidase: An antiviral prodrug activating enzyme U Tehler, CH Nelson, LW Peterson, CJ Provoda, JM Hilfinger, KD Lee, ... Antiviral research 85 (3), 482-489, 2010 | 13 | 2010 |
Simple zinc complex to model substrate binding to zinc enzymes JC Dewar, AS Thakur, WW Brennessel, M Cafiero, LW Peterson, ... Inorganica Chimica Acta 473, 15-19, 2018 | 8 | 2018 |
New peptidomimetic prodrugs of acyclic and cyclic cidofovir: SAR studies of chemical and enzymatic activation mechanisms CE McKenna, LW Peterson, BA Kashemirov, M Serpi, S Mitchell, JS Kim, ... Antiviral Research 2 (82), A75, 2009 | 8 | 2009 |
In vitro transport, activation and antiviral evaluation of new HPMPA prodrugs synthesized on a solid support IS Krylov, LW Peterson, BA Kashemirov, J Breitenbach, K Borysco, ... Antiviral Research 2 (82), A75, 2009 | 8 | 2009 |
Phosphonyl ester conjugates as prodrugs J Hilfinger, CE McKenna, BA Kashemirov, C Pham, K Saejueng, ... US Patent 8,063,209, 2011 | 7 | 2011 |
L-DOPA Dioxygenase Activity on 6-Substituted Dopamine Analogues AM Goldberg, MK Robinson, ES Starr, RN Marasco, AC Alana, ... Biochemistry 60 (32), 2492-2507, 2021 | 5 | 2021 |
Evaluation of hybrid and pure DFT methods for the binding of novel ligands in the tyrosine hydroxylase enzyme R Evans, L Peterson, M Cafiero Computational and Theoretical Chemistry 1140, 145-151, 2018 | 5 | 2018 |