NF-κB-inducing kinase regulates the processing of NF-κB2 p100 G Xiao, EW Harhaj, SC Sun Molecular cell 7 (2), 401-409, 2001 | 1178 | 2001 |
Inhibition of NF-κB signaling by A20 through disruption of ubiquitin enzyme complexes N Shembade, A Ma, EW Harhaj Science 327 (5969), 1135-1139, 2010 | 703 | 2010 |
Regulation of the NF-κB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation G Liao, M Zhang, EW Harhaj, SC Sun Journal of Biological Chemistry 279 (25), 26243-26250, 2004 | 588 | 2004 |
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse M Kamanaka, ST Kim, YY Wan, FS Sutterwala, M Lara-Tejero, JE Galán, ... Immunity 25 (6), 941-952, 2006 | 501 | 2006 |
Retroviral oncoprotein Tax induces processing of NF‐κB2/p100 in T cells: evidence for the involvement of IKKα G Xiao, ME Cvijic, A Fong, EW Harhaj, MT Uhlik, M Waterfield, SC Sun The EMBO journal, 2001 | 379 | 2001 |
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20 N Shembade, NS Harhaj, K Parvatiyar, NG Copeland, NA Jenkins, ... Nature immunology 9 (3), 254-262, 2008 | 305 | 2008 |
Regulation of NF‐κB by deubiquitinases EW Harhaj, VM Dixit Immunological reviews 246 (1), 107-124, 2012 | 303 | 2012 |
IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein EW Harhaj, SC Sun Journal of Biological Chemistry 274 (33), 22911-22914, 1999 | 296 | 1999 |
Deubiquitinases in the regulation of NF-κB signaling EW Harhaj, VM Dixit Cell research 21 (1), 22-39, 2011 | 288 | 2011 |
Regulation of NF-κB signaling by the A20 deubiquitinase N Shembade, EW Harhaj Cellular & molecular immunology 9 (2), 123-130, 2012 | 242 | 2012 |
The ubiquitin‐editing enzyme A20 requires RNF11 to downregulate NF‐κB signalling N Shembade, K Parvatiyar, NS Harhaj, EW Harhaj The EMBO journal 28 (5), 513-522, 2009 | 233 | 2009 |
Essential role for TAX1BP1 in the termination of TNF‐α‐, IL‐1‐and LPS‐mediated NF‐κB and JNK signaling N Shembade, NS Harhaj, DJ Liebl, EW Harhaj The EMBO journal 26 (17), 3910-3922, 2007 | 208 | 2007 |
NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I Tax-mediated NF-κB activation M Uhlik, LF Good, G Xiao, EW Harhaj, E Zandi, M Karin, SC Sun Journal of Biological Chemistry 273 (33), 21132-21136, 1998 | 202 | 1998 |
TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases K Parvatiyar, GN Barber, EW Harhaj Journal of Biological Chemistry 285 (20), 14999-15009, 2010 | 180 | 2010 |
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways MF Tao, PC Scacheri, JM Marinis, EW Harhaj, LE Matesic, DW Abbott Current Biology 19 (15), 1255-1263, 2009 | 159 | 2009 |
Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegeneration K Barmak, E Harhaj, C Grant, T Alefantis, B Wigdahl Virology 308 (1), 1-12, 2003 | 146 | 2003 |
Regulation of RelA subcellular localization by a putative nuclear export signal and p50 EW Harhaj, SC Sun Molecular and cellular biology, 1999 | 139 | 1999 |
The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-κB activation N Shembade, NS Harhaj, M Yamamoto, S Akira, EW Harhaj Journal of virology 81 (24), 13735-13742, 2007 | 131 | 2007 |
Domain-specific interaction with the IκB kinase (IKK) regulatory subunit IKKγ is an essential step in tax-mediated activation of IKK G Xiao, EW Harhaj, SC Sun Journal of Biological Chemistry 275 (44), 34060-34067, 2000 | 131 | 2000 |
The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1 N Shembade, R Pujari, NS Harhaj, DW Abbott, EW Harhaj Nature immunology 12 (9), 834-843, 2011 | 129 | 2011 |