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Edward Harhaj
Edward Harhaj
Associate Professor, Johns Hopkins University
Verified email at jhmi.edu
Title
Cited by
Cited by
Year
NF-κB-inducing kinase regulates the processing of NF-κB2 p100
G Xiao, EW Harhaj, SC Sun
Molecular cell 7 (2), 401-409, 2001
11782001
Inhibition of NF-κB signaling by A20 through disruption of ubiquitin enzyme complexes
N Shembade, A Ma, EW Harhaj
Science 327 (5969), 1135-1139, 2010
7032010
Regulation of the NF-κB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
G Liao, M Zhang, EW Harhaj, SC Sun
Journal of Biological Chemistry 279 (25), 26243-26250, 2004
5882004
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse
M Kamanaka, ST Kim, YY Wan, FS Sutterwala, M Lara-Tejero, JE Galán, ...
Immunity 25 (6), 941-952, 2006
5012006
Retroviral oncoprotein Tax induces processing of NF‐κB2/p100 in T cells: evidence for the involvement of IKKα
G Xiao, ME Cvijic, A Fong, EW Harhaj, MT Uhlik, M Waterfield, SC Sun
The EMBO journal, 2001
3792001
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
N Shembade, NS Harhaj, K Parvatiyar, NG Copeland, NA Jenkins, ...
Nature immunology 9 (3), 254-262, 2008
3052008
Regulation of NF‐κB by deubiquitinases
EW Harhaj, VM Dixit
Immunological reviews 246 (1), 107-124, 2012
3032012
IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein
EW Harhaj, SC Sun
Journal of Biological Chemistry 274 (33), 22911-22914, 1999
2961999
Deubiquitinases in the regulation of NF-κB signaling
EW Harhaj, VM Dixit
Cell research 21 (1), 22-39, 2011
2882011
Regulation of NF-κB signaling by the A20 deubiquitinase
N Shembade, EW Harhaj
Cellular & molecular immunology 9 (2), 123-130, 2012
2422012
The ubiquitin‐editing enzyme A20 requires RNF11 to downregulate NF‐κB signalling
N Shembade, K Parvatiyar, NS Harhaj, EW Harhaj
The EMBO journal 28 (5), 513-522, 2009
2332009
Essential role for TAX1BP1 in the termination of TNF‐α‐, IL‐1‐and LPS‐mediated NF‐κB and JNK signaling
N Shembade, NS Harhaj, DJ Liebl, EW Harhaj
The EMBO journal 26 (17), 3910-3922, 2007
2082007
NF-κB-inducing kinase and IκB kinase participate in human T-cell leukemia virus I Tax-mediated NF-κB activation
M Uhlik, LF Good, G Xiao, EW Harhaj, E Zandi, M Karin, SC Sun
Journal of Biological Chemistry 273 (33), 21132-21136, 1998
2021998
TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases
K Parvatiyar, GN Barber, EW Harhaj
Journal of Biological Chemistry 285 (20), 14999-15009, 2010
1802010
ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways
MF Tao, PC Scacheri, JM Marinis, EW Harhaj, LE Matesic, DW Abbott
Current Biology 19 (15), 1255-1263, 2009
1592009
Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegeneration
K Barmak, E Harhaj, C Grant, T Alefantis, B Wigdahl
Virology 308 (1), 1-12, 2003
1462003
Regulation of RelA subcellular localization by a putative nuclear export signal and p50
EW Harhaj, SC Sun
Molecular and cellular biology, 1999
1391999
The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-κB activation
N Shembade, NS Harhaj, M Yamamoto, S Akira, EW Harhaj
Journal of virology 81 (24), 13735-13742, 2007
1312007
Domain-specific interaction with the IκB kinase (IKK) regulatory subunit IKKγ is an essential step in tax-mediated activation of IKK
G Xiao, EW Harhaj, SC Sun
Journal of Biological Chemistry 275 (44), 34060-34067, 2000
1312000
The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1
N Shembade, R Pujari, NS Harhaj, DW Abbott, EW Harhaj
Nature immunology 12 (9), 834-843, 2011
1292011
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