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Sam Horrell
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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell Stem Cell 29 (2), 217-231. e8, 2022
1712022
Liquid application method for time-resolved analyses by serial synchrotron crystallography
P Mehrabi, EC Schulz, M Agthe, S Horrell, G Bourenkov, D von Stetten, ...
Nature methods 16 (10), 979-982, 2019
852019
Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal
S Horrell, SV Antonyuk, RR Eady, SS Hasnain, MA Hough, RW Strange
IUCrJ 3 (4), 271-281, 2016
622016
Recent structural insights into the function of copper nitrite reductases
S Horrell, D Kekilli, RW Strange, MA Hough
Metallomics 9 (11), 1470-1482, 2017
602017
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine …
H Achdout, A Aimon, E Bar-David, GM Morris
BioRxiv, 2020
532020
A microfluidic flow-focusing device for low sample consumption serial synchrotron crystallography experiments in liquid flow
DCF Monteiro, M Vakili, J Harich, M Sztucki, SM Meier, S Horrell, I Josts, ...
Journal of Synchrotron Radiation 26 (2), 406-412, 2019
392019
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ...
BioRxiv, 2020.10. 29.339317, 2020
362020
Photoreduction and validation of haem–ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction
D Kekilli, T Moreno-Chicano, AK Chaplin, S Horrell, FSN Dworkowski, ...
IUCrJ 4 (3), 263-270, 2017
322017
Visualization of membrane protein crystals in lipid cubic phase using X-ray imaging
AJ Warren, W Armour, D Axford, M Basham, T Connolley, DR Hall, ...
Acta Crystallographica Section D: Biological Crystallography 69 (7), 1252-1259, 2013
302013
xia2. multiplex: a multi-crystal data-analysis pipeline
RJ Gildea, J Beilsten-Edmands, D Axford, S Horrell, P Aller, J Sandy, ...
Acta Crystallographica Section D: Structural Biology 78 (6), 752-769, 2022
292022
Enzyme catalysis captured using multiple structures from one crystal at varying temperatures
S Horrell, D Kekilli, K Sen, RL Owen, FSN Dworkowski, SV Antonyuk, ...
IUCrJ 5 (3), 283-292, 2018
262018
Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases
D Bellini, S Horrell, A Hutchin, CW Phippen, RW Strange, Y Cai, ...
Scientific reports 7 (1), 42166, 2017
262017
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
232023
Making the invisible enemy visible
TI Croll, K Diederichs, F Fischer, CD Fyfe, Y Gao, S Horrell, AP Joseph, ...
Nature structural & molecular biology 28 (5), 404-408, 2021
202021
Homogeneous batch micro-crystallization of proteins from ammonium sulfate
C Stohrer, S Horrell, S Meier, M Sans, D von Stetten, M Hough, ...
Acta Crystallographica Section D: Structural Biology 77 (2), 194-204, 2021
172021
Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase
K Sen, S Horrell, D Kekilli, CW Yong, TW Keal, H Atakisi, DW Moreau, ...
IUCrJ 4 (4), 495-505, 2017
122017
Fixed target serial data collection at diamond light source
S Horrell, D Axford, NE Devenish, A Ebrahim, MA Hough, DA Sherrell, ...
JoVE (Journal of Visualized Experiments), e62200, 2021
72021
Observation of Cation Chromophore Photoisomerization of a Fluorescent Protein Using Millisecond Synchrotron Serial Crystallography and Infrared Vibrational and Visible Spectroscopy
JM Baxter, CDM Hutchison, K Maghlaoui, V Cordon-Preciado, ...
The Journal of Physical Chemistry B 126 (45), 9288-9296, 2022
42022
3DBionotes Covid
JR Macias, R Sanchez-Garcia, P Conesa, E Ramirez-Aportela, ...
Bioinformatics 37 (22), 4258-4260, 2021
42021
TREXX: a new endstation for serial time-resolved crystallography at PETRA III
D von Stetten, M Agthe, G Bourenkov, M Polikarpov, S Horrell, B Yorke, ...
Acta Crystallographica Section A: Foundations and Advances 75, e26-e26, 2019
22019
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Articles 1–20