Opposing effects of adiponectin receptors 1 and 2 on energy metabolism M Bjursell, A Ahnmark, M Bohlooly-Y, L William-Olsson, M Rhedin, ... Diabetes 56 (3), 583-593, 2007 | 350 | 2007 |
Adipocyte differentiation-related protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low–density lipoproteins B Magnusson, L Asp, P Boström, M Ruiz, P Stillemark-Billton, D Lindén, ... Arteriosclerosis, thrombosis, and vascular biology 26 (7), 1566-1571, 2006 | 199 | 2006 |
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice D Lindén, A Ahnmark, P Pingitore, E Ciociola, I Ahlstedt, AC Andréasson, ... Molecular metabolism 22, 49-61, 2019 | 180 | 2019 |
Selective inhibition of FOXO1 activator/repressor balance modulates hepatic glucose handling F Langlet, RA Haeusler, D Lindén, E Ericson, T Norris, A Johansson, ... Cell 171 (4), 824-835. e18, 2017 | 173 | 2017 |
Activation of peroxisome proliferator-activated receptor α increases the expression and activity of microsomal triglyceride transfer protein in the liver C Améen, U Edvardsson, A Ljungberg, L Asp, P Åkerblad, A Tuneld, ... Journal of Biological Chemistry 280 (2), 1224-1229, 2005 | 158 | 2005 |
Sex difference in hepatic peroxisome proliferator-activated receptor α expression: influence of pituitary and gonadal hormones M Jalouli, L Carlsson, C Améen, D Lindén, A Ljungberg, L Michalik, ... Endocrinology 144 (1), 101-109, 2003 | 139 | 2003 |
the emerging role of genetics in precision medicine for patients with non‐alcoholic steatohepatitis B Carlsson, D Lindén, G Brolén, M Liljeblad, M Bjursell, S Romeo, ... Alimentary pharmacology & therapeutics 51 (12), 1305-1320, 2020 | 138 | 2020 |
Liver‐directed overexpression of mitochondrial glycerol‐3‐phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid … D Lindén, L William‐Olsson, A Ahnmark, K Ekroos, C Hallberg, ... The FASEB journal 20 (3), 434-443, 2006 | 138 | 2006 |
PPARα activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes U Edvardsson, A Ljungberg, D Lindén, L William-Olsson, ... Journal of lipid research 47 (2), 329-340, 2006 | 114 | 2006 |
Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis D Lindén, L William-Olsson, M Rhedin, AK Asztély, JC Clapham, ... Journal of lipid research 45 (7), 1279-1288, 2004 | 112 | 2004 |
Human multilineage 3D spheroids as a model of liver steatosis and fibrosis P Pingitore, K Sasidharan, M Ekstrand, S Prill, D Lindén, S Romeo International journal of molecular sciences 20 (7), 1629, 2019 | 109 | 2019 |
Influence of peroxisome proliferator-activated receptor α agonists on the intracellular turnover and secretion of apolipoprotein (Apo) B-100 and ApoB-48 D Lindén, K Lindberg, J Oscarsson, C Claesson, L Asp, L Li, ... Journal of Biological Chemistry 277 (25), 23044-23053, 2002 | 104 | 2002 |
The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids S Prill, A Caddeo, G Baselli, O Jamialahmadi, P Dongiovanni, R Rametta, ... Scientific reports 9 (1), 11585, 2019 | 100 | 2019 |
An oral antisense oligonucleotide for PCSK9 inhibition P Gennemark, K Walter, N Clemmensen, D Rekić, CAM Nilsson, ... Science Translational Medicine 13 (593), eabe9117, 2021 | 88 | 2021 |
Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia M Bohlooly-Y, B Olsson, CEG Bruder, D Lindén, K Sjogren, M Bjursell, ... Diabetes 54 (1), 51-62, 2005 | 86 | 2005 |
PPARα deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins D Lindén, M Alsterholm, H Wennbo, J Oscarsson Journal of Lipid Research 42 (11), 1831-1840, 2001 | 84 | 2001 |
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model A Carreras, LS Pane, R Nitsch, K Madeyski-Bengtson, M Porritt, ... BMC biology 17, 1-14, 2019 | 82 | 2019 |
Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH M Bjursell, M Wedin, T Admyre, M Hermansson, G Böttcher, M Göransson, ... PloS one 8 (5), e64721, 2013 | 79 | 2013 |
Long-term growth hormone excess induces marked alterations in lipoprotein metabolism in mice F Frick, M Bohlooly-Y, D Lindén, B Olsson, J Törnell, S Edén, ... American Journal of Physiology-Endocrinology and Metabolism 281 (6), E1230-E1239, 2001 | 74 | 2001 |
The beneficial effects of n-3 polyunsaturated fatty acids on diet induced obesity and impaired glucose control do not require Gpr120 M Bjursell, X Xu, T Admyre, G Böttcher, S Lundin, R Nilsson, VM Stone, ... PloS one 9 (12), e114942, 2014 | 72 | 2014 |