| Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells D Walter, A Lier, A Geiselhart, FB Thalheimer, S Huntscha, MC Sobotta, ... Nature 520 (7548), 549-552, 2015 | 658 | 2015 |
| Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ... Cell stem cell 15 (4), 507-522, 2014 | 589 | 2014 |
| DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ... Nature genetics 48 (3), 253-264, 2016 | 331 | 2016 |
| DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ... Nature genetics 49 (7), 1052-1060, 2017 | 287 | 2017 |
| Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ... Cell reports 8 (3), 798-806, 2014 | 272 | 2014 |
| Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia CC Oakes, R Claus, L Gu, Y Assenov, J Hüllein, M Zucknick, M Bieg, ... Cancer discovery 4 (3), 348-361, 2014 | 163 | 2014 |
| Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing H Bierhoff, MA Dammert, D Brocks, S Dambacher, G Schotta, I Grummt Molecular cell 54 (4), 675-682, 2014 | 158 | 2014 |
| RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia DB Lipka, T Witte, R Toth, J Yang, M Wiesenfarth, P Nöllke, A Fischer, ... Nature communications 8 (1), 2126, 2017 | 118 | 2017 |
| Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation N Blagitko-Dorfs, P Schlosser, G Greve, D Pfeifer, R Meier, A Baude, ... Leukemia 33 (4), 945-956, 2019 | 90 | 2019 |
| Integrative analysis defines distinct prognostic subgroups of intrahepatic cholangiocarcinoma B Goeppert, R Toth, S Singer, T Albrecht, DB Lipka, P Lutsik, D Brocks, ... Hepatology 69 (5), 2091-2106, 2019 | 83 | 2019 |
| Reactivation of endogenous retroviral elements via treatment with DNMT-and HDAC-inhibitors M Daskalakis, D Brocks, YH Sheng, MS Islam, A Ressnerova, Y Assenov, ... Cell Cycle 17 (7), 811-822, 2018 | 71 | 2018 |
| Intratumor heterogeneity in epigenetic patterns Y Assenov, D Brocks, C Gerhäuser Seminars in cancer biology 51, 12-21, 2018 | 67 | 2018 |
| Mobile genomics: tools and techniques for tackling transposons K O'Neill, D Brocks, MG Hammell Philosophical Transactions of the Royal Society B 375 (1795), 20190345, 2020 | 47 | 2020 |
| Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite … DB Lipka, Q Wang, N Cabezas-Wallscheid, D Klimmeck, D Weichenhan, ... Cell Cycle 13 (22), 3476-3487, 2014 | 40 | 2014 |
| ICGC Early Onset Prostate Cancer Project: Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ... Cell Rep 8 (3), 798-806, 2014 | 19 | 2014 |
| Musical patterns for comparative epigenomics D Brocks Clinical Epigenetics 7, 1-5, 2015 | 16 | 2015 |
| Single cell analysis reveals dynamics of transposable element transcription following epigenetic de-repression D Brocks, E Chomsky, Z Mukamel, A Lifshitz, A Tanay BioRxiv, 462853, 2018 | 13 | 2018 |
Christoph PlassProfessor für Epigenetik, DKFZ, HeidelbergVerified email at dkfz.de
