| Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ... Journal of proteomics 79, 180-194, 2013 | 172 | 2013 |
| The bile acid deoxycholic acid (DCA) at neutral pH activates NF-κB and induces IL-8 expression in oesophageal cells in vitro GJS Jenkins, K Harries, SH Doak, A Wilmes, AP Griffiths, JN Baxter, ... Carcinogenesis 25 (3), 317-323, 2004 | 168 | 2004 |
| Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ... Toxicology in Vitro 30 (1), 117-127, 2015 | 120 | 2015 |
| Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity A Wilmes, D Crean, S Aydin, W Pfaller, P Jennings, MO Leonard Toxicology In Vitro 25 (3), 613-622, 2011 | 95 | 2011 |
| Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines A Wilmes, K Bargh, C Kelly, PT Northcote, JH Miller Molecular pharmaceutics 4 (2), 269-280, 2007 | 95 | 2007 |
| The molecular and cellular aspects of arthritis due to alphavirus infections: lesson learned from Ross River virus NE Rulli, J Melton, A Wilmes, G Ewart, S Mahalingam Annals of the New York Academy of Sciences 1102 (1), 96-108, 2007 | 94 | 2007 |
| Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes A Limonciel, L Aschauer, A Wilmes, S Prajczer, MO Leonard, W Pfaller, ... Toxicology in Vitro 25 (8), 1855-1862, 2011 | 85 | 2011 |
| Delineation of the key aspects in the regulation of epithelial monolayer formation L Aschauer, LN Gruber, W Pfaller, A Limonciel, TJ Athersuch, R Cavill, ... Molecular and cellular biology 33 (13), 2535-2550, 2013 | 76 | 2013 |
| Ross River virus: molecular and cellular aspects of disease pathogenesis NE Rulli, A Suhrbier, L Hueston, MT Heise, D Tupanceska, A Zaid, ... Pharmacology & therapeutics 107 (3), 329-342, 2005 | 71 | 2005 |
| Peloruside B, a potent antitumor macrolide from the New Zealand marine sponge Mycale hentscheli: isolation, structure, total synthesis, and bioactivity AJ Singh, CX Xu, X Xu, LM West, A Wilmes, A Chan, E Hamel, JH Miller, ... The Journal of organic chemistry 75 (1), 2-10, 2010 | 66 | 2010 |
| Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: a transcriptomic study L Aschauer, A Limonciel, A Wilmes, S Stanzel, A Kopp-Schneider, ... Toxicology in Vitro 30 (1), 106-116, 2015 | 51 | 2015 |
| Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model P Jennings, C Weiland, A Limonciel, KM Bloch, R Radford, L Aschauer, ... Archives of toxicology 86, 571-589, 2012 | 50 | 2012 |
| Peloruside-and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII-and βIII-Tubulin IsotypesPeloruside-and Laulimalide … A Kanakkanthara, A Wilmes, A O'Brate, D Escuin, A Chan, A Gjyrezi, ... Molecular cancer therapeutics 10 (8), 1419-1429, 2011 | 50 | 2011 |
| Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells A Limonciel, A Wilmes, L Aschauer, R Radford, KM Bloch, T McMorrow, ... Archives of toxicology 86, 1741-1751, 2012 | 48 | 2012 |
| Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing D Crean, P Bellwon, L Aschauer, A Limonciel, K Moenks, P Hewitt, ... Toxicology in Vitro 30 (1), 128-137, 2015 | 43 | 2015 |
| Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq A Limonciel, G Ates, G Carta, A Wilmes, M Watzele, PJ Shepard, ... Archives of toxicology 92, 2517-2531, 2018 | 36 | 2018 |
| Differentiation of human iPSCs into functional podocytes C Rauch, E Feifel, G Kern, C Murphy, F Meier, W Parson, M Beilmann, ... PLoS One 13 (9), e0203869, 2018 | 35 | 2018 |
| Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing A Limonciel, K Moenks, S Stanzel, GL Truisi, C Parmentier, L Aschauer, ... Toxicology in Vitro 30 (1), 7-18, 2015 | 35 | 2015 |
| Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells A Wilmes, D O’Sullivan, A Chan, C Chandrahasen, I Paterson, ... Cancer chemotherapy and pharmacology 68, 117-126, 2011 | 35 | 2011 |
| The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods A Krebs, BMA van Vugt-Lussenburg, T Waldmann, W Albrecht, J Boei, ... Archives of Toxicology 94, 2435-2461, 2020 | 30 | 2020 |
