JNK signaling in stem cell self-renewal and differentiation T Semba, R Sammons, X Wang, X Xie, KN Dalby, NT Ueno International journal of molecular sciences 21 (7), 2613, 2020 | 58 | 2020 |
Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer M Gagliardi, MK Pitner, J Park, X Xie, H Saso, RA Larson, RM Sammons, ... Scientific reports 10 (1), 8537, 2020 | 36 | 2020 |
Targeting ERK beyond the boundaries of the kinase active site in melanoma RM Sammons, R Ghose, KY Tsai, KN Dalby Molecular carcinogenesis 58 (9), 1551-1570, 2019 | 33 | 2019 |
A novel class of common docking domain inhibitors that prevent ERK2 activation and substrate phosphorylation RM Sammons, NA Perry, Y Li, EJ Cho, A Piserchio, DP Zamora-Olivares, ... ACS chemical biology 14 (6), 1183-1194, 2019 | 30 | 2019 |
From in silico discovery to intracellular activity: targeting JNK–protein interactions with small molecules TS Kaoud, C Yan, S Mitra, CC Tseng, J Jose, JM Taliaferro, ... ACS medicinal chemistry letters 3 (9), 721-725, 2012 | 30 | 2012 |
Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo TS Kaoud, WH Johnson, ND Ebelt, A Piserchio, D Zamora-Olivares, ... Nature Communications 10 (1), 5232, 2019 | 22 | 2019 |
1, 3-diketone analogs as selective lysyl hydroxylase 2 (LH2) antagonists J Lee, H Guo, Y Maghsoud, EA Vázquez-Montelongo, Z Jing, S Wang, ... Available at SSRN 4314687, 2022 | 2 | 2022 |
A Toolbox of Structural Biology and Enzyme Kinetics Reveals the Case for ERK Docking Site Inhibition RM Sammons, KN Dalby Next Generation Kinase Inhibitors: Moving Beyond the ATP Binding/Catalytic …, 2020 | 1 | 2020 |
Discovery of a covalent inhibitor of ERK docking-interactions that inhibits A375 melanoma cells proliferation TS Kaoud, WH Johnson, ND Ebelt, A Piserchio, M Warthaka, M Cano, ... Cancer Research 76 (14_Supplement), 3771-3771, 2016 | 1 | 2016 |
Preclinical development of JNK-targeted therapy for triple-negative breast cancer. X Xie, TS Kaoud, R Edupuganti, RM Sammons, GN Hortobagyi, NT Ueno, ... Cancer Research 73 (8_Supplement), 3241-3241, 2013 | 1 | 2013 |
Identification and biochemical characterization of small molecule inhibitors of ERK2 that target the D-recruitment site. RM Sammons, EJ Cho, KN Dalby Methods in Enzymology 690, 445-499, 2023 | | 2023 |
High-Throughput Assay for Identifying Diverse Antagonists of the Binding Interaction between the ACE2 Receptor and the Dynamic Spike Proteins of SARS-CoV-2 RM Sammons, AL Bohanon, A Kowtha, A Dejong, EJ Cho, TS Kaoud, ... ACS Infectious Diseases 8 (11), 2259-2270, 2022 | | 2022 |
Cover Image, Volume 58, Issue 9 RM Sammons, R Ghose, KY Tsai, KN Dalby Molecular Carcinogenesis 58 (9), i-i, 2019 | | 2019 |
Targeting multi-functional ERK-protein complexes in vivo TS Kaoud, WH Johnson, ND Ebelt, A Piserchio, D Zamora-Olivares, ... Cancer Research 79 (13_Supplement), 3872-3872, 2019 | | 2019 |
Inhibiting multifunctional ERK-protein complexes for cancer therapy T Kaoud, WH Johnson, ND Ebelt, A Piserchio, SV Ravenstein, ... EUROPEAN JOURNAL OF CANCER 103, E51-E51, 2018 | | 2018 |
Unconventional approaches to kinase inhibition: covalent inhibitors and docking site inhibitors of mitogen-activated protein kinases RM Sammons | | 2018 |
Silencing of ERK2 reverses EMT and suppresses the CSC phenotype, inhibiting lung metastasis in triple-negative breast cancer MK Pitner, H Saso, R Larson, RM Sammons, H Chen, C Wei, G Chauhan, ... Cancer Research 76 (14_Supplement), 1624-1624, 2016 | | 2016 |
Covalent inhibition of ERK docking interactions TS Kaoud, WH Johnson, A Piserchio, ND Ebelt, M Warthaka, M Cano, ... The FASEB Journal 30, 856.11-856.11, 2016 | | 2016 |
Inhibition of the TRPM7 kinase domain inhibits breast cancer cell migration and invasion and tumor metastasis TS Kaoud, X Xie, J Park, CDJ Tavares, S Mitra, M Cano, RM Sammons, ... Cancer Research 75 (15_Supplement), 3569-3569, 2015 | | 2015 |
A high-throughput fluorescence anisotropy screening for discovery of inhibitors that target the D-recruitment site of ERK in vitro and in cells RM Sammons, TS Kaoud, AK Devkota, EJ Cho, KN Dalby Cancer Research 75 (15_Supplement), 3648-3648, 2015 | | 2015 |