IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models H Ågerstam, N Hansen, S von Palffy, C Sandén, K Reckzeh, C Karlsson, ... Blood, The Journal of the American Society of Hematology 128 (23), 2683-2693, 2016 | 102 | 2016 |
CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting N Landberg, S von Palffy, M Askmyr, H Lilljebjörn, C Sandén, M Rissler, ... haematologica 103 (3), 447, 2018 | 53 | 2018 |
IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome N Landberg, N Hansen, M Askmyr, H Ågerstam, C Lassen, M Rissler, ... Leukemia 30 (1), 255-258, 2016 | 50 | 2016 |
Clonal competition within complex evolutionary hierarchies shapes AML over time C Sandén, H Lilljebjörn, C Orsmark Pietras, R Henningsson, KH Saba, ... Nature Communications 11 (1), 579, 2020 | 33 | 2020 |
Primary cells in BCR/FGFR1‐positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib N Landberg, A Dreimane, M Rissler, R Billström, H Ågerstam European Journal of Haematology 99 (5), 442-448, 2017 | 23 | 2017 |
Dysregulated lipid synthesis by oncogenic IDH1 mutation is a targetable synthetic lethal vulnerability D Thomas, M Wu, Y Nakauchi, M Zheng, CAL Thompson-Peach, K Lim, ... Cancer discovery 13 (2), 496-515, 2023 | 17 | 2023 |
Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells M Askmyr, H Ågerstam, H Lilljebjörn, N Hansen, C Karlsson, S von Palffy, ... Blood cancer journal 4 (12), e269-e269, 2014 | 17 | 2014 |
SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function N Hansen, H Ågerstam, M Wahlestedt, N Landberg, M Askmyr, M Ehinger, ... Leukemia 27 (1), 130-135, 2013 | 13 | 2013 |
A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells S von Palffy, N Landberg, C Sandén, D Zacharaki, M Shah, N Nakamichi, ... haematologica 105 (8), 2095, 2020 | 12 | 2020 |
Clinical and genomic characterization of patients diagnosed with the provisional entity acute myeloid leukemia with BCR‐ABL1, a Swedish population‐based study C Orsmark‐Pietras, N Landberg, F Lorenz, B Uggla, M Höglund, ... Genes, Chromosomes and Cancer 60 (6), 426-433, 2021 | 10 | 2021 |
Reprogramming cancer into antigen-presenting cells as a novel immunotherapy MH Linde, AC Fan, T Köhnke, AC Trotman-Grant, SF Gurev, P Phan, ... Cancer Discovery 13 (5), 1164-1185, 2023 | 9 | 2023 |
Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells M Askmyr, S Von Palffy, N Hansen, N Landberg, C Högberg, M Rissler, ... Plos one 12 (10), e0186035, 2017 | 3 | 2017 |
IDH1-Mutant Preleukemic Hematopoietic Stem Cells Can Be Eliminated by Inhibition of Oxidative Phosphorylation N Landberg, T Köhnke, Y Feng, Y Nakauchi, AC Fan, MH Linde, ... Blood cancer discovery 5 (2), 114-131, 2024 | 2 | 2024 |
The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML S von Palffy, H Thorsson, P Peña-Martínez, N Puente-Moncada, ... Blood Advances 7 (7), 1204-1218, 2023 | 2 | 2023 |
Immunosuppression in Isocitrate Dehydrogenase Mutated Acute Myeloid Leukemia JW Tai, G Li, K Tanaka, J Gopakumar, C Zhou, MH Linde, A Villar-Prados, ... Blood 142, 1335, 2023 | | 2023 |
Novel agents and uses thereof T Fioretos, N Landberg, C Sanden US Patent App. 17/782,526, 2023 | | 2023 |
Targeting IDH1-Mutated Pre-Leukemic Hematopoietic Stem Cells in Myeloid Disease, Including CCUS and AML N Landberg, T Koehnke, Y Nakauchi, A Fan, D Karigane, D Thomas, ... Blood 140 (Supplement 1), 2234-2235, 2022 | | 2022 |
Cell Surface Markers as Therapeutic Targets in Myeloid Leukemia N Landberg | | 2020 |
Modeling Chronic Myeloid Leukemia in Immunodeficient Mice Reveals an Inflammatory State with Expansion of Aberrant Mast Cells and Accumulation of Pre B Cells M Askmyr, H Agerstam, H Lilljebjörn, N Hansen, C Karlsson, N Landberg, ... Blood 124 (21), 3132, 2014 | | 2014 |
Funding sources DRN LANDBERG, N Landberg, A Dreimane, M Rissler, R Billström, ... | | |