| Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2 K Yamanaka, H Ishikawa, Y Megumi, F Tokunaga, M Kanie, TA Rouault, ... Nature cell biology 5 (4), 336-340, 2003 | 222 | 2003 |
| Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2 H Ishikawa, M Kato, H Hori, K Ishimori, T Kirisako, F Tokunaga, K Iwai Molecular cell 19 (2), 171-181, 2005 | 188 | 2005 |
| Direct observation of fast protein conformational switching H Ishikawa, K Kwak, JK Chung, S Kim, MD Fayer Proceedings of the National Academy of Sciences 105 (25), 8619-8624, 2008 | 161 | 2008 |
| Substrate binding and protein conformational dynamics measured by 2D-IR vibrational echo spectroscopy IJ Finkelstein, H Ishikawa, S Kim, AM Massari, MD Fayer Proceedings of the National Academy of Sciences 104 (8), 2637-2642, 2007 | 117 | 2007 |
| Probing dynamics of complex molecular systems with ultrafast 2D IR vibrational echo spectroscopy IJ Finkelstein, J Zheng, H Ishikawa, S Kim, K Kwak, MD Fayer Physical Chemistry Chemical Physics 9 (13), 1533-1549, 2007 | 117 | 2007 |
| Neuroglobin dynamics observed with ultrafast 2D-IR vibrational echo spectroscopy H Ishikawa, IJ Finkelstein, S Kim, K Kwak, JK Chung, K Wakasugi, ... Proceedings of the National Academy of Sciences 104 (41), 16116-16121, 2007 | 85 | 2007 |
| Disulfide bond influence on protein structural dynamics probed with 2D-IR vibrational echo spectroscopy H Ishikawa, S Kim, K Kwak, K Wakasugi, MD Fayer Proceedings of the National Academy of Sciences 104 (49), 19309-19314, 2007 | 84 | 2007 |
| Identification of histidine 77 as the axial heme ligand of carbonmonoxy CooA by picosecond time-resolved resonance Raman spectroscopy T Uchida, H Ishikawa, K Ishimori, I Morishima, H Nakajima, S Aono, ... Biochemistry 39 (42), 12747-12752, 2000 | 82 | 2000 |
| Heme environmental structure of CooA is modulated by the target DNA binding: Evidence from resonance Raman spectroscopy and CO rebinding kinetics T Uchida, H Ishikawa, S Takahashi, K Ishimori, I Morishima, K Ohkubo, ... Journal of Biological Chemistry 273 (32), 19988-19992, 1998 | 79 | 1998 |
| Binding of CO at the Pro2 Side Is Crucial for the Activation of CO-sensing Transcriptional Activator CooA: 1H NMR SPECTROSCOPIC STUDIES K Yamamoto, H Ishikawa, S Takahashi, K Ishimori, I Morishima Journal of Biological Chemistry 276 (15), 11473-11476, 2001 | 70 | 2001 |
| Observing vibrational energy flow in a protein with the spatial resolution of a single amino acid residue N Fujii, M Mizuno, H Ishikawa, Y Mizutani The journal of physical chemistry letters 5 (18), 3269-3273, 2014 | 61 | 2014 |
| Unusual heme binding in the bacterial iron response regulator protein: spectral characterization of heme binding to the heme regulatory motif H Ishikawa, M Nakagaki, A Bamba, T Uchida, H Hori, MR O’Brian, K Iwai, ... Biochemistry 50 (6), 1016-1022, 2011 | 53 | 2011 |
| Structural basis for oxygen sensing and signal transduction of the heme-based sensor protein Aer2 from Pseudomonas aeruginosa H Sawai, H Sugimoto, Y Shiro, H Ishikawa, Y Mizutani, S Aono Chemical communications 48 (52), 6523-6525, 2012 | 43 | 2012 |
| Iron hemiporphycene as a functional prosthetic group for myoglobin S Neya, K Imai, H Hori, H Ishikawa, K Ishimori, D Okuno, S Nagatomo, ... Inorganic chemistry 42 (5), 1456-1461, 2003 | 43 | 2003 |
| Ligand migration in human myoglobin: steric effects of isoleucine 107 (G8) on O2 and CO binding H Ishikawa, T Uchida, S Takahashi, K Ishimori, I Morishima Biophysical journal 80 (3), 1507-1517, 2001 | 36 | 2001 |
| Identification of crucial histidines for heme binding in the N-terminal domain of the heme-regulated eIF2α kinase T Inuzuka, BG Yun, H Ishikawa, S Takahashi, H Hori, RL Matts, K Ishimori, ... Journal of Biological Chemistry 279 (8), 6778-6782, 2004 | 33 | 2004 |
| Identification of Essential Histidine Residues Involved in Heme Binding and Hemozoin Formation in Heme Detoxification Protein from Plasmodium falciparum K Nakatani, H Ishikawa, S Aono, Y Mizutani Scientific reports 4 (1), 6137, 2014 | 31 | 2014 |
| Heme-binding properties of heme detoxification protein from Plasmodium falciparum K Nakatani, H Ishikawa, S Aono, Y Mizutani Biochemical and Biophysical Research Communications 439 (4), 477-480, 2013 | 25 | 2013 |
| Protein dynamics of isolated chains of recombinant human hemoglobin elucidated by time-resolved resonance Raman spectroscopy K Yamada, H Ishikawa, Y Mizutani The Journal of Physical Chemistry B 116 (6), 1992-1998, 2012 | 22 | 2012 |
| Intersubunit communication via changes in hemoglobin quaternary structures revealed by time-resolved resonance Raman spectroscopy: direct observation of the Perutz mechanism K Yamada, H Ishikawa, M Mizuno, N Shibayama, Y Mizutani The Journal of Physical Chemistry B 117 (41), 12461-12468, 2013 | 21 | 2013 |
