The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis GJ Starrett, EM Luengas, JL McCann, D Ebrahimi, NA Temiz, RP Love, ... Nature communications 7 (1), 12918, 2016 | 166 | 2016 |
A single nucleotide polymorphism in human APOBEC3C enhances restriction of lentiviruses CJ Wittkopp, MB Adolph, LI Wu, L Chelico, M Emerman PLoS pathogens 12 (10), e1005865, 2016 | 65 | 2016 |
Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B MB Adolph, RP Love, Y Feng, L Chelico Nucleic acids research 45 (20), 11925-11940, 2017 | 56 | 2017 |
Retroviral restriction factor APOBEC3G delays the initiation of DNA synthesis by HIV-1 reverse transcriptase MB Adolph, J Webb, L Chelico PloS one 8 (5), e64196, 2013 | 53 | 2013 |
Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure YZ McDaniel, D Wang, RP Love, MB Adolph, N Mohammadzadeh, ... Nucleic acids research 48 (3), 1353-1371, 2020 | 50 | 2020 |
Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization MB Adolph, A Ara, Y Feng, CJ Wittkopp, M Emerman, JS Fraser, L Chelico Nucleic acids research 45 (6), 3378-3394, 2017 | 48 | 2017 |
Mechanism of enhanced HIV restriction by virion coencapsidated cytidine deaminases APOBEC3F and APOBEC3G A Ara, RP Love, TB Follack, KA Ahmed, MB Adolph, L Chelico Journal of virology 91 (3), 10.1128/jvi. 02230-16, 2017 | 48 | 2017 |
Natural polymorphisms and oligomerization of human APOBEC3H contribute to single-stranded DNA scanning ability Y Feng, RP Love, A Ara, TT Baig, MB Adolph, L Chelico Journal of Biological Chemistry 290 (45), 27188-27203, 2015 | 45 | 2015 |
Biochemical basis of APOBEC3 deoxycytidine deaminase activity on diverse DNA substrates MB Adolph, RP Love, L Chelico ACS infectious diseases 4 (3), 224-238, 2018 | 42 | 2018 |
RADX controls RAD51 filament dynamics to regulate replication fork stability MB Adolph, TM Mohamed, S Balakrishnan, C Xue, F Morati, M Modesti, ... Molecular cell 81 (5), 1074-1083. e5, 2021 | 27 | 2021 |
RADX prevents genome instability by confining replication fork reversal to stalled forks A Krishnamoorthy, J Jackson, T Mohamed, M Adolph, A Vindigni, ... Molecular cell 81 (14), 3007-3017. e5, 2021 | 25 | 2021 |
APOBEC3 host restriction factors of HIV-1 can change the template switching frequency of reverse transcriptase MB Adolph, A Ara, L Chelico Journal of molecular biology 431 (7), 1339-1352, 2019 | 9 | 2019 |
The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis. Nat Commun 7: 12918 GJ Starrett, EM Luengas, JL McCann, D Ebrahimi, NA Temiz, RP Love, ... | 9 | 2016 |
APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response KL Conner, AN Shaik, KA Marshall, AM Floyd, E Ekinci, J Lindquist, ... NAR cancer 2 (4), zcaa033, 2020 | 6 | 2020 |
Oligomerization of DNA replication regulatory protein RADX is essential to maintain replication fork stability T Mohamed, MB Adolph, D Cortez Journal of Biological Chemistry 298 (3), 2022 | 4 | 2022 |
Corrigendum: Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B. MB Adolph, RP Love, Y Feng, L Chelico Nucleic Acids Research 46 (22), 12190-12191, 2018 | 2 | 2018 |
Structure of RADX and mechanism for regulation of RAD51 nucleofilaments S Balakrishnan, M Adolph, MS Tsai, T Akizuki, K Gallagher, D Cortez, ... Proceedings of the National Academy of Sciences 121 (12), e2316491121, 2024 | | 2024 |
Abstract IA024: Mechanistic insights into how RADX regulates RAD51 nucleoprotein filaments to maintain genome stability and control replication stress responses M Adolph, S Balakrishnan, W Chazin, D Cortez Cancer Research 84 (1_Supplement), IA024-IA024, 2024 | | 2024 |
Mechanistic insights into how RADX regulates RAD51 nucleoprotein filaments to maintain genome stability and control replication stress responses M Adolph, S Balakrishnan, W Chazin, D Cortez CANCER RESEARCH 84 (1), 2024 | | 2024 |
CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity MB Adolph, AS Garje, S Balakrishnan, F Morati, M Modesti, WJ Chazin, ... Journal of Molecular Biology 435 (19), 168236, 2023 | | 2023 |