David H. Cribbs
David H. Cribbs
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Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
A microfluidic culture platform for CNS axonal injury, regeneration and transport
AM Taylor, M Blurton-Jones, SW Rhee, DH Cribbs, CW Cotman, NL Jeon
Nature methods 2 (8), 599-605, 2005
Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
S Oddo, L Billings, JP Kesslak, DH Cribbs, FM LaFerla
Neuron 43 (3), 321-332, 2004
Structure‐activity analyses of β‐amyloid peptides: contributions of the β25–35 region to aggregation and neurotoxicity
CJ Pike, AJ Walencewicz‐Wasserman, J Kosmoski, DH Cribbs, CG Glabe, ...
Journal of neurochemistry 64 (1), 253-265, 1995
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
Gene expression changes in the course of normal brain aging are sexually dimorphic
NC Berchtold, DH Cribbs, PD Coleman, J Rogers, E Head, R Kim, ...
Proceedings of the National Academy of Sciences 105 (40), 15605-15610, 2008
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
DH Cribbs, NC Berchtold, V Perreau, PD Coleman, J Rogers, AJ Tenner, ...
Journal of neuroinflammation 9, 1-18, 2012
Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer’s disease model
M Kitazawa, D Cheng, MR Tsukamoto, MA Koike, PD Wes, V Vasilevko, ...
The Journal of Immunology 187 (12), 6539-6549, 2011
Microfluidic multicompartment device for neuroscience research
AM Taylor, SW Rhee, CH Tu, DH Cribbs, CW Cotman, NL Jeon
Langmuir 19 (5), 1551-1556, 2003
Reduction of soluble Aβ and tau, but not soluble Aβ alone, ameliorates cognitive decline in transgenic mice with plaques and tangles
S Oddo, V Vasilevko, A Caccamo, M Kitazawa, DH Cribbs, FM LaFerla
Journal of Biological Chemistry 281 (51), 39413-39423, 2006
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
DC Whitcomb, J LaRusch, AM Krasinskas, L Klei, JP Smith, RE Brand, ...
Nature genetics 44 (12), 1349-1354, 2012
Adjuvant‐dependent modulation of Th1 and Th2 responses to immunization with β‐amyloid
DH Cribbs, A Ghochikyan, V Vasilevko, M Tran, I Petrushina, N Sadzikava, ...
International immunology 15 (4), 505-514, 2003
Patterned cell culture inside microfluidic devices
SW Rhee, AM Taylor, CH Tu, DH Cribbs, CW Cotman, NL Jeon
Lab on a Chip 5 (1), 102-107, 2005
Prototype Alzheimer’s disease vaccine using the immunodominant B cell epitope from β-amyloid and promiscuous T cell epitope pan HLA DR-binding peptide
MG Agadjanyan, A Ghochikyan, I Petrushina, V Vasilevko, N Movsesyan, ...
The Journal of Immunology 174 (3), 1580-1586, 2005
Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
KE Nichol, WW Poon, AI Parachikova, DH Cribbs, CG Glabe, CW Cotman
Journal of neuroinflammation 5, 1-15, 2008
A novel Alzheimer disease locus located near the gene encoding tau protein
G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ...
Molecular psychiatry 21 (1), 108-117, 2016
Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase
L Tong, GA Prieto, EA Kramár, ED Smith, DH Cribbs, G Lynch, ...
Journal of Neuroscience 32 (49), 17714-17724, 2012
Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease
NC Berchtold, PD Coleman, DH Cribbs, J Rogers, DL Gillen, CW Cotman
Neurobiology of aging 34 (6), 1653-1661, 2013
Localization and cell association of C1q in Alzheimer's disease brain
A Afagh, BJ Cummings, DH Cribbs, CW Cotman, AJ Tenner
Experimental neurology 138 (1), 22-32, 1996
Assessment of the genetic variance of late-onset Alzheimer's disease
PG Ridge, KB Hoyt, K Boehme, S Mukherjee, PK Crane, JL Haines, ...
Neurobiology of aging 41, 200. e13-200. e20, 2016
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