Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing H Atcha, A Jairaman, JR Holt, VS Meli, RR Nagalla, ... Nature communications 12 (1), 3256, 2021 | 283 | 2021 |
Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming MP Matheu, S Othy, ML Greenberg, TX Dong, M Schuijs, K Deswarte, ... Nature communications 6 (1), 6219, 2015 | 138 | 2015 |
Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop F Marangoni, A Zhakyp, M Corsini, SN Geels, E Carrizosa, M Thelen, ... Cell 184 (15), 3998-4015. e19, 2021 | 127 | 2021 |
Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses JL Bolton, AK Short, S Othy, CL Kooiker, M Shao, BG Gunn, J Beck, X Bai, ... Cell reports 38 (13), 2022 | 89 | 2022 |
Immunomodulation by intravenous immunoglobulin: role of regulatory T cells MS Maddur, S Othy, P Hegde, J Vani, S Lacroix-Desmazes, J Bayry, ... Journal of Clinical Immunology 30, 4-8, 2010 | 87 | 2010 |
T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse TX Dong, S Othy, A Jairaman, J Skupsky, A Zavala, I Parker, JL Dynes, ... Elife 6, e32417, 2017 | 77 | 2017 |
Intravenous gammaglobulin inhibits encephalitogenic potential of pathogenic T cells and interferes with their trafficking to the central nervous system, implicating sphingosine … S Othy, P Hegde, S Topçu, M Sharma, MS Maddur, S Lacroix-Desmazes, ... The Journal of Immunology 190 (9), 4535-4541, 2013 | 73 | 2013 |
Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses A Jairaman, S Othy, JL Dynes, AV Yeromin, A Zavala, ML Greenberg, ... Science advances 7 (28), eabg5859, 2021 | 67 | 2021 |
Regulatory T cells suppress Th17 cell Ca2+ signaling in the spinal cord during murine autoimmune neuroinflammation S Othy, A Jairaman, JL Dynes, TX Dong, C Tune, AV Yeromin, A Zavala, ... Proceedings of the National Academy of Sciences 117 (33), 20088-20099, 2020 | 58 | 2020 |
Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant LL McIntyre, SA Greilach, S Othy, I Sears-Kraxberger, B Wi, ... Neurobiology of disease 140, 104868, 2020 | 56 | 2020 |
Sialylation may be dispensable for reciprocal modulation of helper T cells by intravenous immunoglobulin S Othy, S Topçu, C Saha, P Kothapalli, S Lacroix‐Desmazes, ... European journal of immunology 44 (7), 2059-2063, 2014 | 52 | 2014 |
TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia A Jairaman, A McQuade, A Granzotto, YJ Kang, JP Chadarevian, ... Elife 11, e73021, 2022 | 44 | 2022 |
Intermittent Ca2+ signals mediated by Orai1 regulate basal T cell motility TX Dong, S Othy, ML Greenberg, A Jairaman, C Akunwafo, S Leverrier, ... Elife 6, e27827, 2017 | 41 | 2017 |
Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis G Coulis, D Jaime, C Guerrero-Juarez, JM Kastenschmidt, PK Farahat, ... Science advances 9 (27), eadd9984, 2023 | 34 | 2023 |
Effect of IVIg on human dendritic cell-mediated antigen uptake and presentation: role of lipid accumulation S Othy, P Bruneval, S Topçu, I Dugail, F Delers, S Lacroix-Desmazes, ... Journal of autoimmunity 39 (3), 168-172, 2012 | 24 | 2012 |
Cxcl17 -/- mice develop exacerbated disease in a T cell-dependent autoimmune model M Hernández-Ruiz, S Othy, C Herrera, HT Nguyen, G Arrevillaga-Boni, ... Journal of leukocyte biology 105 (5), 1027-1039, 2019 | 19 | 2019 |
Calcium dynamics in astrocytes during cell injury NM Wakida, V Gomez-Godinez, H Li, J Nguyen, EK Kim, JL Dynes, S Othy, ... Frontiers in Bioengineering and Biotechnology 8, 912, 2020 | 18 | 2020 |
Effect of CC chemokine receptor 4 antagonism on the evolution of experimental autoimmune encephalomyelitis S Othy, S Topçu, SV Kaveri, J Bayry Proceedings of the National Academy of Sciences 109 (37), E2412-E2413, 2012 | 10 | 2012 |
Imaging regulatory T cell dynamics and suppression of T cell priming mediated by CTLA4 MP Matheu, S Othy, ML Greenberg, TX Dong, M Schuijs, K Deswarte, ... Nature communications 6, 6219, 2015 | 6 | 2015 |
Interruption of the intratumor CD8+ T cell: Treg crosstalk improves the efficacy of PD-1 immunotherapy SN Geels, A Moshensky, RS Sousa, C Murat, MA Bustos, BL Walker, ... Cancer Cell 42 (6), 1051-1066. e7, 2024 | 4 | 2024 |