Pierre Sonveaux
Pierre Sonveaux
University of Louvain (UCL) Medical School
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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
P Sonveaux, F Végran, T Schroeder, MC Wergin, J Verrax, ZN Rabbani, ...
The Journal of clinical investigation 118 (12), 3930-3942, 2008
Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis
F Végran, R Boidot, C Michiels, P Sonveaux, O Feron
Cancer research 71 (7), 2550-2560, 2011
A mitochondrial switch promotes tumor metastasis
PE Porporato, VL Payen, J Pérez-Escuredo, CJ De Saedeleer, P Danhier, ...
Cell reports 8 (3), 754-766, 2014
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis
P Sonveaux, T Copetti, CJ De Saedeleer, F Vegran, J Verrax, ...
PloS one 7 (3), e33418, 2012
Regulation of HIF-1α stability through S-nitrosylation
F Li, P Sonveaux, ZN Rabbani, S Liu, B Yan, Q Huang, Z Vujaskovic, ...
Molecular cell 26 (1), 63-74, 2007
Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review
PE Porporato, S Dhup, RK Dadhich, T Copetti, P Sonveaux
Frontiers in pharmacology 2, 49, 2011
Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis
S Dhup, R Kumar Dadhich, P Ettore Porporato, P Sonveaux
Current pharmaceutical design 18 (10), 1319-1330, 2012
Monocarboxylate transporters in cancer
VL Payen, E Mina, VF Van Hée, PE Porporato, P Sonveaux
Molecular metabolism 33, 48-66, 2020
Monocarboxylate transporters in the brain and in cancer
J Pérez-Escuredo, VF Van Hée, M Sboarina, J Falces, VL Payen, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (10), 2481-2497, 2016
Hsp90 and caveolin are key targets for the proangiogenic nitric oxide–mediated effects of statins
A Brouet, P Sonveaux, C Dessy, S Moniotte, JL Balligand, O Feron
Circulation research 89 (10), 866-873, 2001
Gut microbiota-derived propionate reduces cancer cell proliferation in the liver
LB Bindels, P Porporato, EM Dewulf, J Verrax, AM Neyrinck, JC Martin, ...
British journal of cancer 107 (8), 1337-1344, 2012
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells
CJ De Saedeleer, T Copetti, PE Porporato, J Verrax, O Feron, ...
Public Library of Science 7 (10), e46571, 2012
Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial …
A Brouet, P Sonveaux, C Dessy, JL Balligand, O Feron
Journal of Biological Chemistry 276 (35), 32663-32669, 2001
Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors
R Boidot, F Végran, A Meulle, A Le Breton, C Dessy, P Sonveaux, ...
Cancer research 72 (4), 939-948, 2012
Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice
PE Porporato, VL Payen, CJ De Saedeleer, V Préat, JP Thissen, O Feron, ...
Angiogenesis 15, 581-592, 2012
Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implications for tumor radiotherapy
P Sonveaux, A Brouet, X Havaux, V Grégoire, C Dessy, JL Balligand, ...
Cancer Research 63 (5), 1012-1019, 2003
PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing
KK Chereddy, CH Her, M Comune, C Moia, A Lopes, PE Porporato, ...
Journal of Controlled Release 194, 138-147, 2014
Caveolin-1 expression is critical for vascular endothelial growth factor–induced ischemic hindlimb collateralization and nitric oxide–mediated angiogenesis
P Sonveaux, P Martinive, J DeWever, Z Batova, G Daneau, M Pelat, ...
Circulation research 95 (2), 154-161, 2004
Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway
VL Payen, PE Porporato, B Baselet, P Sonveaux
Cellular and Molecular Life Sciences 73, 1333-1348, 2016
Cancer metabolism in space and time: beyond the Warburg effect
P Danhier, P Bański, VL Payen, D Grasso, L Ippolito, P Sonveaux, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1858 (8), 556-572, 2017
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