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Juan Antonio Hernández Bort, MSc, PhD
Juan Antonio Hernández Bort, MSc, PhD
Verified email at univie.ac.at
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Cited by
Year
Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering
M Hackl, T Jakobi, J Blom, D Doppmeier, K Brinkrolf, R Szczepanowski, ...
Journal of biotechnology 153 (1-2), 62-75, 2011
1252011
Dynamic mRNA and miRNA profiling of CHO‐K1 suspension cell cultures
JAH Bort, M Hackl, H Höflmayer, V Jadhav, E Harreither, N Kumar, ...
Biotechnology journal 7 (4), 500-515, 2012
1062012
Stable overexpression of miR-17 enhances recombinant protein production of CHO cells
V Jadhav, M Hackl, G Klanert, JAH Bort, R Kunert, J Grillari, N Borth
Journal of biotechnology 175, 38-44, 2014
862014
A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells
V Jadhav, M Hackl, JA Hernandez Bort, M Wieser, E Harreither, R Kunert, ...
Biotechnology and bioengineering 109 (6), 1376-1385, 2012
642012
Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth
M Taschwer, M Hackl, JAH Bort, C Leitner, N Kumar, U Puc, J Grass, ...
Journal of biotechnology 157 (2), 295-303, 2012
612012
Utilization and evaluation of CHO‐specific sequence databases for mass spectrometry based proteomics
P Meleady, R Hoffrogge, M Henry, O Rupp, JH Bort, C Clarke, K Brinkrolf, ...
Biotechnology and bioengineering 109 (6), 1386-1394, 2012
582012
CHO‐K1 host cells adapted to growth in glutamine‐free medium by FACS‐assisted evolution
JAH Bort, B Stern, N Borth
Biotechnology Journal 5 (10), 1090-1097, 2010
482010
A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines
G Klanert, V Jadhav, V Shanmukam, A Diendorfer, M Karbiener, ...
Journal of Biotechnology 235, 150-161, 2016
262016
Reduced quenching and extraction time for mammalian cells using filtration and syringe extraction
JAH Bort, V Shanmukam, M Pabst, M Windwarder, L Neumann, ...
Journal of Biotechnology 182, 97-103, 2014
232014
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
KJ la Cour Karottki, H Hefzi, S Li, LE Pedersen, PN Spahn, C Joshi, ...
Metabolic engineering 66, 114-122, 2021
202021
Assessment of the percentage of full recombinant adeno-associated virus particles in a gene therapy drug using CryoTEM
SIM Colomb-Delsuc M, Raim R, Fiedler C, Reuberger S, Lengler J, Nordström R ...
Plos One 3 (17), 2022
9*2022
Challenges in the downstream process of gene therapy products
JA Hernandez Bort
Am Pharm Rev. 22 (4), 2019
62019
Proton-transfer-reaction mass spectrometry (PTR-MS) for online monitoring of glucose depletion and cell concentrations in HEK 293 gene therapy processes
HBJA Bayer B, Maccani A, Jahn J, Duerkop M, Kapeller E, Pletzenauer R, Kraus ...
Plos 1 44 (1), 77-88, 2022
4*2022
Scaling strategy for cell and gene therapy bioreactors based on turbulent parameters
D Iurashev, PA Jones, N Andreev, Y Wang, T Iwata‐Kajihara, B Kraus, ...
Biotechnology Journal 19 (1), 2300235, 2024
22024
Comprehensive mRNA‐sequencing‐based characterization of three HEK‐293 cell lines during an rAAV production process for gene therapy applications
M Pistek, CI Kahlig, M Hackl, S Unterthurner, B Kraus, R Grabherr, ...
Biotechnology Journal 18 (8), 2200513, 2023
22023
Factors affecting recombinant Adeno-Associated Virus titers during triple-plasmid transient transfection in HEK-293 cells
M Pistek, P Andorfer, R Grabherr, B Kraus, JAH Bort
2024
Characterizing the Biopotency of Truncated Transgene Variants in rAAV8 viral vectors: Essential Considerations for Gene Therapy Applications
C Fiedler, J Lengler, B Gruber, M Scheindel, C Büngener, ...
2024
Optimizing VLP production in gene therapy: Opportunities and challenges for in silico modeling
L Zehetner, D Széliová, B Kraus, M Graninger, J Zanghellini, ...
Biotechnology Journal 18 (7), 2200636, 2023
2023
Differential logistic PCA for large-scale comparison of GSMMs and pathway analysis
L Zehetner, D Szeliova, B Kraus, J Hernandez Bort, J Zanghellini
bioRxiv, 2023.11. 27.568810, 2023
2023
In silico tools to accelerate process development of cell and gene therapies
JA Bort
HUMAN GENE THERAPY 33 (23-24), A105-A105, 2022
2022
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