Stebėti
Christine Levesque
Pavadinimas
Cituota
Cituota
Metai
Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases
GL Becker, Y Lu, K Hardes, B Strehlow, C Levesque, I Lindberg, ...
Journal of Biological Chemistry 287 (26), 21992-22003, 2012
1252012
Cellular constituents of the prostate stroma: Key contributors to prostate cancer progression and therapy resistance
C Levesque, PS Nelson
Cold Spring Harbor perspectives in medicine 8 (8), a030510, 2018
812018
The Multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cells
C Levesque, M Fugère, A Kwiatkowska, F Couture, R Desjardins, ...
Journal of Medicinal Chemistry 55 (23), 10501-10511, 2012
572012
Design, synthesis, and structure–activity relationship studies of a potent PACE4 inhibitor
A Kwiatkowska, F Couture, C Levesque, K Ly, R Desjardins, ...
Journal of medicinal chemistry 57 (1), 98-109, 2014
422014
PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction, increased apoptosis and impaired neovascularisation
C Levesque, F Couture, A Kwiatkowska, R Desjardins, B Guérin, ...
Oncotarget 6 (6), 3680, 2015
372015
Implications of proprotein convertases in ovarian cancer cell proliferation and tumor progression: insights for PACE4 as a therapeutic target
R Longuespée, F Couture, C Levesque, A Kwiatkowska, R Desjardins, ...
Translational Oncology 7 (3), 410-419, 2014
372014
Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin
H Gagnon, S Beauchemin, A Kwiatkowska, F Couture, F D’Anjou, ...
Journal of Medicinal Chemistry 57 (1), 29-41, 2014
362014
Chymase inhibitor-sensitive synthesis of endothelin-1 (1–31) by recombinant mouse mast cell protease 4 and human chymase
W Semaan, L Desbiens, M Houde, J Labonte, H Gagnon, D Yamamoto, ...
Biochemical pharmacology 94 (2), 91-100, 2015
252015
PACE4-based molecular targeting of prostate cancer using an engineered 64Cu-radiolabeled peptide inhibitor
F Couture, C Levesque, V Dumulon-Perreault, S Ait-Mohand, F D’Anjou, ...
Neoplasia 16 (8), 634-643, 2014
172014
Novel Insights into Structure–Activity Relationships of N‐Terminally Modified PACE4 Inhibitors
A Kwiatkowska, F Couture, C Levesque, K Ly, S Beauchemin, ...
ChemMedChem 11 (3), 289-301, 2016
162016
Positional scanning identifies the molecular determinants of a high affinity multi-leucine inhibitor for furin and PACE4
I Małuch, C Levesque, A Kwiatkowska, F Couture, K Ly, R Desjardins, ...
Journal of Medicinal Chemistry 60 (7), 2732-2744, 2017
102017
Multi-Leu PACE4 inhibitor retention within cells is PACE4 dependent and a prerequisite for antiproliferative activity
F Couture, K Ly, C Levesque, A Kwiatkowska, S Ait-Mohand, ...
BioMed Research International 2015, 2015
72015
Selection of metric for indoor‐outdoor source apportionment of metals in PM2.5: mg/kg versus ng/m3
PE Rasmussen, C Levesque, O Butler, M Chénier, HD Gardner
Indoor air 32 (1), e12924, 2022
52022
Identification and quantification of trace metal (loid) s in water-extractable road dust nanoparticles using SP-ICP-MS
ML Avramescu, K Casey, C Levesque, J Chen, C Wiseman, ...
Science of The Total Environment 924, 171720, 2024
12024
Relationships between house characteristics and exposures to metal (loid) s and synthetic organic contaminants evaluated using settled indoor dust
PE Rasmussen, C Kubwabo, HD Gardner, C Levesque, S Beauchemin
International Journal of Environmental Research and Public Health 19 (16), 10329, 2022
12022
Metals in aerosolizable and water-extractable ultrafine road dust particles
S Beauchemin, ML Avramescu, C Levesque, K Casey, CLS Wiseman, ...
Goldschmidt 2023 Conference, 2023
2023
Viable Clostridium botulinum spores not detected in the household dust of major Canadian cities
RA Harris, M Blondin-Brosseau, C Levesque, PE Rasmussen, ...
Epidemiology & Infection 151, e154, 2023
2023
Targeting immunosuppressive alterations in the tumor microenvironment resulting from therapy-induced DNA damage responses
W Jin, A Zhao, C Levesque, I Colman, PS Nelson
CANCER RESEARCH 76, 2016
2016
Abstract A04: Targeting immunosuppressive alterations in the tumor microenvironment resulting from therapy-induced DNA damage responses
W Jin, A Zhao, C Levesque, I Colman, PS Nelson
Cancer Research 76 (15_Supplement), A04-A04, 2016
2016
A bone marrow vascular niche model to study the effects of a DNA Damage Secretory Program in promoting prostate cancer treatment resistance
C Levesque, X Zhao, CM Ghajar, PS Nelson
CANCER RESEARCH 76, 2016
2016
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Straipsniai 1–20