Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases GL Becker, Y Lu, K Hardes, B Strehlow, C Levesque, I Lindberg, ... Journal of Biological Chemistry 287 (26), 21992-22003, 2012 | 126 | 2012 |
Cellular constituents of the prostate stroma: Key contributors to prostate cancer progression and therapy resistance C Levesque, PS Nelson Cold Spring Harbor perspectives in medicine 8 (8), a030510, 2018 | 82 | 2018 |
The Multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cells C Levesque, M Fugère, A Kwiatkowska, F Couture, R Desjardins, ... Journal of Medicinal Chemistry 55 (23), 10501-10511, 2012 | 58 | 2012 |
Design, synthesis, and structure–activity relationship studies of a potent PACE4 inhibitor A Kwiatkowska, F Couture, C Levesque, K Ly, R Desjardins, ... Journal of medicinal chemistry 57 (1), 98-109, 2014 | 42 | 2014 |
PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction, increased apoptosis and impaired neovascularisation C Levesque, F Couture, A Kwiatkowska, R Desjardins, B Guérin, ... Oncotarget 6 (6), 3680, 2015 | 38 | 2015 |
Implications of proprotein convertases in ovarian cancer cell proliferation and tumor progression: insights for PACE4 as a therapeutic target R Longuespée, F Couture, C Levesque, A Kwiatkowska, R Desjardins, ... Translational Oncology 7 (3), 410-419, 2014 | 38 | 2014 |
Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin H Gagnon, S Beauchemin, A Kwiatkowska, F Couture, F D’Anjou, ... Journal of Medicinal Chemistry 57 (1), 29-41, 2014 | 36 | 2014 |
Chymase inhibitor-sensitive synthesis of endothelin-1 (1–31) by recombinant mouse mast cell protease 4 and human chymase W Semaan, L Desbiens, M Houde, J Labonte, H Gagnon, D Yamamoto, ... Biochemical pharmacology 94 (2), 91-100, 2015 | 25 | 2015 |
PACE4-based molecular targeting of prostate cancer using an engineered 64Cu-radiolabeled peptide inhibitor F Couture, C Levesque, V Dumulon-Perreault, S Ait-Mohand, F D’Anjou, ... Neoplasia 16 (8), 634-643, 2014 | 18 | 2014 |
Novel Insights into Structure–Activity Relationships of N‐Terminally Modified PACE4 Inhibitors A Kwiatkowska, F Couture, C Levesque, K Ly, S Beauchemin, ... ChemMedChem 11 (3), 289-301, 2016 | 16 | 2016 |
Positional scanning identifies the molecular determinants of a high affinity multi-leucine inhibitor for furin and PACE4 I Małuch, C Levesque, A Kwiatkowska, F Couture, K Ly, R Desjardins, ... Journal of Medicinal Chemistry 60 (7), 2732-2744, 2017 | 10 | 2017 |
Multi-Leu PACE4 inhibitor retention within cells is PACE4 dependent and a prerequisite for antiproliferative activity F Couture, K Ly, C Levesque, A Kwiatkowska, S Ait-Mohand, ... BioMed Research International 2015, 2015 | 7 | 2015 |
Selection of metric for indoor‐outdoor source apportionment of metals in PM2.5: mg/kg versus ng/m3 PE Rasmussen, C Levesque, O Butler, M Chénier, HD Gardner Indoor air 32 (1), e12924, 2022 | 6 | 2022 |
Relationships between house characteristics and exposures to metal (loid) s and synthetic organic contaminants evaluated using settled indoor dust PE Rasmussen, C Kubwabo, HD Gardner, C Levesque, S Beauchemin International Journal of Environmental Research and Public Health 19 (16), 10329, 2022 | 2 | 2022 |
Identification and quantification of trace metal (loid) s in water-extractable road dust nanoparticles using SP-ICP-MS ML Avramescu, K Casey, C Levesque, J Chen, C Wiseman, ... Science of The Total Environment 924, 171720, 2024 | 1 | 2024 |
Carcinogenic metal (loid) s in house dust compared to soil: concentrations and gastric bioaccessibility S Beauchemin, ML Avramescu, C Levesque, PE Rasmussen Environmental Research, 119175, 2024 | | 2024 |
Metals in aerosolizable and water-extractable ultrafine road dust particles S Beauchemin, ML Avramescu, C Levesque, K Casey, CLS Wiseman, ... Goldschmidt 2023 Conference, 2023 | | 2023 |
Viable Clostridium botulinum spores not detected in the household dust of major Canadian cities RA Harris, M Blondin-Brosseau, C Levesque, PE Rasmussen, ... Epidemiology & Infection 151, e154, 2023 | | 2023 |
Targeting immunosuppressive alterations in the tumor microenvironment resulting from therapy-induced DNA damage responses W Jin, A Zhao, C Levesque, I Colman, PS Nelson CANCER RESEARCH 76, 2016 | | 2016 |
Abstract A04: Targeting immunosuppressive alterations in the tumor microenvironment resulting from therapy-induced DNA damage responses W Jin, A Zhao, C Levesque, I Colman, PS Nelson Cancer Research 76 (15_Supplement), A04-A04, 2016 | | 2016 |