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John Beale
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Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins
A Ebrahim, T Moreno-Chicano, MV Appleby, AK Chaplin, JH Beale, ...
IUCrJ 6 (4), 543-551, 2019
532019
Crystal structures of the extracellular domain from PepT1 and PepT2 provide novel insights into mammalian peptide transport
JH Beale, JL Parker, F Samsudin, AL Barrett, A Senan, LE Bird, D Scott, ...
Structure 23 (10), 1889-1899, 2015
432015
Successful sample preparation for serial crystallography experiments
JH Beale, R Bolton, SA Marshall, EV Beale, SB Carr, A Ebrahim, ...
Journal of applied crystallography 52 (6), 1385-1396, 2019
302019
High-throughput structures of protein–ligand complexes at room temperature using serial femtosecond crystallography
T Moreno-Chicano, A Ebrahim, D Axford, MV Appleby, JH Beale, ...
IUCrJ 6 (6), 1074-1085, 2019
292019
Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography
A Ebrahim, MV Appleby, D Axford, J Beale, T Moreno-Chicano, ...
Acta Crystallographica Section D: Structural Biology 75 (2), 151-159, 2019
292019
Reducing sample consumption for serial crystallography using acoustic drop ejection
B Davy, D Axford, JH Beale, A Butryn, P Docker, A Ebrahim, G Leen, ...
Journal of synchrotron radiation 26 (5), 1820-1825, 2019
242019
X-ray–induced photoreduction of heme metal centers rapidly induces active-site perturbations in a protein-independent manner
V Pfanzagl, JH Beale, H Michlits, D Schmidt, T Gabler, C Obinger, ...
Journal of Biological Chemistry 295 (39), 13488-13501, 2020
212020
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
A Butryn, PS Simon, P Aller, P Hinchliffe, RN Massad, G Leen, CL Tooke, ...
Nature communications 12 (1), 1-7, 2021
172021
Non-contact universal sample presentation for room temperature macromolecular crystallography using acoustic levitation
RH Morris, ER Dye, D Axford, MI Newton, JH Beale, PT Docker
Scientific reports 9 (1), 1-10, 2019
132019
How best to use photons
G Winter, RJ Gildea, NG Paterson, J Beale, M Gerstel, D Axford, ...
Acta Crystallographica Section D: Structural Biology 75 (3), 242-261, 2019
132019
Anaerobic fixed-target serial crystallography
P Rabe, JH Beale, A Butryn, P Aller, A Dirr, PA Lang, DN Axford, SB Carr, ...
IUCrJ 7 (5), 901-912, 2020
102020
Structure of the aliphatic sulfonate-binding protein SsuA from Escherichia coli
J Beale, SY Lee, S Iwata, K Beis
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
82010
Macromolecular X-ray crystallography: soon to be a road less travelled?
JH Beale
Acta Crystallographica Section D: Structural Biology 76 (5), 400-405, 2020
32020
Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature
T Moreno-Chicano, LM Carey, D Axford, JH Beale, RB Doak, ...
IUCrJ 9 (5), 2022
12022
Probing ligand binding of endothiapepsin bytemperature-resolved'macromolecular crystallography
CY Huang, S Aumonier, S Engilberge, D Eris, KML Smith, F Leonarski, ...
Acta Crystallographica Section D: Structural Biology 78 (8), 2022
12022
Versatile microporous polymer-based supports for serial macromolecular crystallography
I Martiel, JH Beale, A Karpik, CY Huang, L Vera, N Olieric, M Wranik, ...
Acta Crystallographica Section D: Structural Biology 77 (9), 2021
12021
Release of a photopharmacological drug from its protein target captured by time-resolved serial crystallography
M Wranik, T Weinert, C Slavov, T Masini, A Furrer, N Gaillard, D Gioia, ...
2022
Fixed-Targets for Serial Protein Crystallography at SwissFEL
M Carrillo, J Beale, C Padeste
Foundations of Crystallography 78, a279, 2022
2022
Optimizing the Growth of Endothiapepsin Crystals for Serial Crystallography Experiments
JH Beale, ME Marsh
JoVE (Journal of Visualized Experiments), e61896, 2021
2021
Structural and biophysical characterisation of the extra-cellular domains from the mammalian peptide transporters, PepT1 and PepT2
JH Beale
2015
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Articles 1–20