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Brian Chorley
Brian Chorley
Verified email at epa.gov
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Year
Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha
BN Chorley, MR Campbell, X Wang, M Karaca, D Sambandan, F Bangura, ...
Nucleic acids research 40 (15), 7416-7429, 2012
5832012
Nrf2-regulated PPARγ expression is critical to protection against acute lung injury in mice
HY Cho, W Gladwell, X Wang, B Chorley, D Bell, SP Reddy, ...
American journal of respiratory and critical care medicine 182 (2), 170-182, 2010
2432010
Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies
BN Chorley, X Wang, MR Campbell, GS Pittman, MA Noureddine, DA Bell
Mutation Research/Reviews in Mutation Research 659 (1-2), 147-157, 2008
2422008
Identification of polymorphic antioxidant response elements in the human genome
X Wang, DJ Tomso, BN Chorley, HY Cho, VG Cheung, SR Kleeberger, ...
Human molecular genetics 16 (10), 1188-1200, 2007
1972007
Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase Cδ-mediated mechanism
JA Park, F He, LD Martin, Y Li, BN Chorley, KB Adler
The American journal of pathology 167 (3), 651-661, 2005
1382005
Applying'omics technologies in chemicals risk assessment: Report of an ECETOC workshop
R Buesen, BN Chorley, B da Silva Lima, G Daston, L Deferme, T Ebbels, ...
Regulatory Toxicology and Pharmacology 91, S3-S13, 2017
1202017
Novel hematopoietic target genes in the NRF2-mediated transcriptional pathway
MR Campbell, M Karaca, KN Adamski, BN Chorley, X Wang, DA Bell
Oxidative medicine and cellular longevity 2013, 2013
1052013
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer
X Wang, BN Chorley, GS Pittman, SR Kleeberger, J Brothers, G Liu, ...
PloS one 5 (8), e11934, 2010
692010
Tipping the balance: hepatotoxicity and the 4 apical key events of hepatic steatosis
MM Angrish, JP Kaiser, CA McQueen, BN Chorley
Toxicological Sciences 150 (2), 261-268, 2016
652016
MicroRNA biomarkers of toxicity in biological matrices
AH Harrill, SD McCullough, CE Wood, JJ Kahle, BN Chorley
Toxicological Sciences 152 (2), 264-272, 2016
602016
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology
JA Harrill, MR Viant, CL Yauk, M Sachana, TW Gant, SS Auerbach, ...
Regulatory Toxicology and Pharmacology 125, 105020, 2021
542021
Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts
MA Noureddine, D Menendez, MR Campbell, OJ Bandele, MM Horvath, ...
PLoS genetics 5 (5), e1000462, 2009
512009
A polymorphic antioxidant response element links NRF2/sMAF binding to enhanced MAPT expression and reduced risk of Parkinsonian disorders
X Wang, MR Campbell, SE Lacher, HY Cho, M Wan, CL Crowl, ...
Cell reports 15 (4), 830-842, 2016
482016
Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor
J Rooney, K Oshida, N Vasani, B Vallanat, N Ryan, BN Chorley, X Wang, ...
PloS one 13 (8), e0200004, 2018
452018
Enhanced expression of mucin genes in a guinea pig model of allergic asthma
Y Li, LD Martin, M Minnicozzi, S Greenfeder, J Fine, CA Pettersen, ...
American journal of respiratory cell and molecular biology 25 (5), 644-651, 2001
442001
Epigenetic applications in adverse outcome pathways and environmental risk evaluation
MM Angrish, P Allard, SD McCullough, IL Druwe, L Helbling Chadwick, ...
Environmental Health Perspectives 126 (4), 045001, 2018
432018
Moving toward integrating gene expression profiling into high-throughput testing: A gene expression biomarker accurately predicts estrogen receptor α modulation in a microarray …
N Ryan, B Chorley, RR Tice, R Judson, JC Corton
Toxicological Sciences 151 (1), 88-103, 2016
432016
Framework for the quality assurance of’omics technologies considering GLP requirements
HM Kauffmann, H Kamp, R Fuchs, BN Chorley, L Deferme, T Ebbels, ...
Regulatory Toxicology and Pharmacology 91, S27-S35, 2017
382017
A generic transcriptomics reporting framework (TRF) for ‘omics data processing and analysis
TW Gant, UG Sauer, SD Zhang, BN Chorley, J Hackermüller, ...
Regulatory Toxicology and Pharmacology 91, S36-S45, 2017
362017
Editor’s highlight: mechanistic toxicity tests based on an adverse outcome pathway network for hepatic steatosis
MM Angrish, CA McQueen, E Cohen-Hubal, M Bruno, Y Ge, BN Chorley
Toxicological Sciences 159 (1), 159-169, 2017
362017
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