Gilbert Di Paolo
Gilbert Di Paolo
Denali Therapeutics
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Phosphoinositides in cell regulation and membrane dynamics
G Di Paolo, P De Camilli
Nature 443 (7112), 651-657, 2006
Linking lipids to Alzheimer's disease: cholesterol and beyond
G Di Paolo, TW Kim
Nature Reviews Neuroscience 12 (5), 284-296, 2011
Essential role of phosphoinositide metabolism in synaptic vesicle recycling
O Cremona, G Di Paolo, MR Wenk, A Lüthi, WT Kim, K Takei, L Daniell, ...
Cell 99 (2), 179-188, 1999
RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson’s disease risk
DA MacLeod, H Rhinn, T Kuwahara, A Zolin, G Di Paolo, BD McCabe, ...
Neuron 77 (3), 425-439, 2013
Comparative lipidomic analysis of mouse and human brain with Alzheimer disease
RB Chan, TG Oliveira, EP Cortes, LS Honig, KE Duff, SA Small, MR Wenk, ...
Journal of Biological Chemistry 287 (4), 2678-2688, 2012
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons
JW Wu, M Herman, L Liu, S Simoes, CM Acker, H Figueroa, JI Steinberg, ...
Journal of Biological Chemistry 288 (3), 1856-1870, 2013
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1γ by the FERM domain of talin
G Di Paolo, L Pellegrini, K Letinic, G Cestra, R Zoncu, S Voronov, ...
Nature 420 (6911), 85-89, 2002
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking
GD Paolo, HS Moskowitz, K Gipson, MR Wenk, S Voronov, M Obayashi, ...
Nature 431 (7007), 415-422, 2004
TREM2 regulates microglial cholesterol metabolism upon chronic phagocytic challenge
AA Nugent, K Lin, B Van Lengerich, S Lianoglou, L Przybyla, SS Davis, ...
Neuron 105 (5), 837-854. e9, 2020
Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis
N Ringstad, H Gad, P Löw, G Di Paolo, L Brodin, O Shupliakov, ...
Neuron 24 (1), 143-154, 1999
The Sac1 Domain of SYNJ1 Identified Mutated in a Family with Early‐Onset Progressive Parkinsonism with Generalized Seizures
CE Krebs, S Karkheiran, JC Powell, M Cao, V Makarov, H Darvish, ...
Human mutation 34 (9), 1200-1207, 2013
Fission and uncoating of synaptic clathrin-coated vesicles are perturbed by disruption of interactions with the SH3 domain of endophilin
H Gad, N Ringstad, P Löw, O Kjaerulff, J Gustafsson, M Wenk, G Di Paolo, ...
Neuron 27 (2), 301-312, 2000
The role of lipids in the control of autophagy
C Dall'Armi, KA Devereaux, G Di Paolo
Current Biology 23 (1), R33-R45, 2013
Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry
MR Wenk, L Lucast, G Di Paolo, AJ Romanelli, SF Suchy, RL Nussbaum, ...
Nature biotechnology 21 (7), 813-817, 2003
Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells
B Liu, BW Lee, K Nakanishi, A Villasante, R Williamson, J Metz, J Kim, ...
Nature biomedical engineering 2 (5), 293-303, 2018
PIP kinase Iγ is the major PI (4, 5) P2 synthesizing enzyme at the synapse
MR Wenk, L Pellegrini, VA Klenchin, G Di Paolo, S Chang, L Daniell, ...
Neuron 32 (1), 79-88, 2001
Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice
G Di Paolo, S Sankaranarayanan, MR Wenk, L Daniell, E Perucco, ...
Neuron 33 (5), 789-804, 2002
Oligomeric amyloid-β peptide disrupts phosphatidylinositol-4, 5-bisphosphate metabolism
DE Berman, C Dall'Armi, SV Voronov, LBJ McIntire, H Zhang, AZ Moore, ...
Nature neuroscience 11 (5), 547-554, 2008
Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system
E Morel, Z Chamoun, ZM Lasiecka, RB Chan, RL Williamson, ...
Nature communications 4 (1), 2250, 2013
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