Stebėti
Giedrius Gasiunas
Giedrius Gasiunas
CasZyme; Vilnius University Life Science Center Institute of Biotechnology
Patvirtintas el. paštas caszyme.com - Pagrindinis puslapis
Pavadinimas
Cituota
Cituota
Metai
Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
G Gasiunas, R Barrangou, P Horvath, V Siksnys
Proceedings of the National Academy of Sciences 109 (39), E2579-E2586, 2012
30562012
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
R Sapranauskas, G Gasiunas, C Fremaux, R Barrangou, P Horvath, ...
Nucleic acids research 39 (21), 9275-9282, 2011
12752011
Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system
T Sinkunas, G Gasiunas, C Fremaux, R Barrangou, P Horvath, V Siksnys
The EMBO journal 30 (7), 1335-1342, 2011
5052011
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
MD Szczelkun, MS Tikhomirova, T Sinkunas, G Gasiunas, T Karvelis, ...
Proceedings of the National Academy of Sciences 111 (27), 9798-9803, 2014
4242014
crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus
T Karvelis, G Gasiunas, A Miksys, R Barrangou, P Horvath, V Siksnys
RNA biology 10 (5), 841-851, 2013
3012013
In vitro reconstitution of Cascade‐mediated CRISPR immunity in Streptococcus thermophilus
T Sinkunas, G Gasiunas, SP Waghmare, MJ Dickman, R Barrangou, ...
The EMBO journal 32 (3), 385-394, 2013
2822013
Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome
M Müller, CM Lee, G Gasiunas, TH Davis, TJ Cradick, V Siksnys, G Bao, ...
Molecular Therapy 24 (3), 636-644, 2016
2322016
RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX
V Siksnys, G Gasiunas, T Karvelis, A Lubys, L Zaliauskiene, M Glemzaite, ...
US Patent App. 14/385,857, 2015
2112015
RNA-directed DNA cleavage by the Cas9-crRNA complex
G Gasiunas, T Karvelis
US Patent 9,637,739, 2017
2002017
Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements
T Karvelis, G Gasiunas, J Young, G Bigelyte, A Silanskas, M Cigan, ...
Genome biology 16 (1), 1-13, 2015
1872015
Molecular mechanisms of CRISPR-mediated microbial immunity
G Gasiunas, T Sinkunas, V Siksnys
Cellular and molecular life sciences 71 (3), 449-465, 2014
1382014
RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing?
G Gasiunas, V Siksnys
Trends in Microbiology 21 (11), 562-567, 2013
1002013
RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX
V Siksnys, G Gasiunas, T Karvelis
US Patent App. 14/743,764, 2015
962015
Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging
V Labrie, OJ Buske, E Oh, R Jeremian, C Ptak, G Gasiūnas, A Maleckas, ...
Nature structural & molecular biology 23 (6), 566-573, 2016
872016
A catalogue of biochemically diverse CRISPR-Cas9 orthologs
G Gasiunas, JK Young, T Karvelis, D Kazlauskas, T Urbaitis, ...
Nature communications 11 (1), 1-10, 2020
712020
RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX
V Siksnys, G Gasiunas, T Karvelis, A Lubys, L Zaliauskiene, M Glemzaite, ...
US Patent App. 15/834,578, 2018
572018
RNA-directed DNA cleavage by the Cas9-crRNA complex
G Gasiūnas, T Karvelis
US Patent 10,844,378, 2020
472020
Programmable DNA cleavage in vitro by Cas9
T Karvelis, G Gasiunas, V Siksnys
Biochemical Society Transactions 41 (6), 1401-1406, 2013
432013
Structure of the DNA-bound spacer capture complex of a type II CRISPR-Cas system
M Wilkinson, G Drabavicius, A Silanskas, G Gasiunas, V Siksnys, ...
Molecular cell 75 (1), 90-101. e5, 2019
402019
Mva1269I: a monomeric type IIS restriction endonuclease from Micrococcus varians with two EcoRI-and FokI-like catalytic domains
E Armalyte, JM Bujnicki, J Giedriene, G Gasiunas, J Kosiński, A Lubys
Journal of Biological Chemistry 280 (50), 41584-41594, 2005
372005
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