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David MacLean
David MacLean
University of Rochester Medical Center
Verified email at urmc.rochester.edu
Title
Cited by
Cited by
Year
The α2δ-1-NMDA receptor complex is critically involved in neuropathic pain development and gabapentin therapeutic actions
J Chen, L Li, SR Chen, H Chen, JD Xie, RE Sirrieh, DM MacLean, ...
Cell reports 22 (9), 2307-2321, 2018
2522018
Dynamic membrane protein topological switching upon changes in phospholipid environment
H Vitrac, DM MacLean, V Jayaraman, M Bogdanov, W Dowhan
Proceedings of the National Academy of Sciences 112 (45), 13874-13879, 2015
912015
Stargazin modulation of AMPA receptors
SA Shaikh, DM Dolino, G Lee, S Chatterjee, DM MacLean, C Flatebo, ...
Cell reports 17 (2), 328-335, 2016
652016
Role of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism
S Ramaswamy, D Cooper, N Poddar, DM MacLean, A Rambhadran, ...
Journal of Biological Chemistry 287 (52), 43557-43564, 2012
612012
Stargazin promotes closure of the AMPA receptor ligand-binding domain
DM MacLean, SS Ramaswamy, M Du, JR Howe, V Jayaraman
Journal of General Physiology 144 (6), 503-512, 2014
582014
Ancestral reconstruction of the ligand-binding pocket of Family CG protein-coupled receptors
D Kuang, Y Yao, D MacLean, M Wang, DR Hampson, BSW Chang
Proceedings of the National Academy of Sciences 103 (38), 14050-14055, 2006
582006
The structure–energy landscape of NMDA receptor gating
DM Dolino, S Chatterjee, DM MacLean, C Flatebo, LDC Bishop, ...
Nature chemical biology 13 (12), 1232-1238, 2017
552017
Amino-terminal domain tetramer organization and structural effects of zinc binding in the N-methyl-D-aspartate (NMDA) receptor
RE Sirrieh, DM MacLean, V Jayaraman
Journal of Biological Chemistry 288 (31), 22555-22564, 2013
522013
Coupling structure with function in acid‐sensing ion channels: challenges in pursuit of proton sensors
ML Rook, M Musgaard, DM MacLean
The Journal of physiology 599 (2), 417-430, 2021
512021
Na+/Cl− dipole couples agonist binding to kainate receptor activation
AYC Wong, DM MacLean, D Bowie
Journal of Neuroscience 27 (25), 6800-6809, 2007
402007
Comparing the performance of mScarlet-I, mRuby3, and mCherry as FRET acceptors for mNeonGreen
TW McCullock, DM MacLean, PJ Kammermeier
PloS one 15 (2), e0219886, 2020
392020
A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc
RE Sirrieh, DM MacLean, V Jayaraman
Journal of General Physiology 146 (2), 173-181, 2015
392015
Proton-mediated conformational changes in an acid-sensing ion channel
SS Ramaswamy, DM MacLean, AA Gorfe, V Jayaraman
Journal of Biological Chemistry 288 (50), 35896-35903, 2013
392013
β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery
ML Rook, A Williamson, JD Lueck, M Musgaard, DM Maclean
Elife 9, e51111, 2020
382020
Subtype-dependent N-methyl-D-aspartate receptor amino-terminal domain conformations and modulation by spermine
RE Sirrieh, DM MacLean, V Jayaraman
Journal of Biological Chemistry 290 (20), 12812-12820, 2015
382015
Conformational spread and dynamics in allostery of NMDA receptors
RJ Durham, N Paudyal, E Carrillo, NK Bhatia, DM Maclean, V Berka, ...
Proceedings of the National Academy of Sciences 117 (7), 3839-3847, 2020
362020
Mechanism of Modulation of AMPA Receptors by TARPγ8
E Carrillo, SA Shaikh, V Berka, LM Nowak, V Jayaraman
Biophysical Journal 118 (3), 191a, 2020
332020
Dual effects of TARP γ-2 on glutamate efficacy can account for AMPA receptor autoinactivation
ID Coombs, DM MacLean, V Jayaraman, M Farrant, SG Cull-Candy
Cell reports 20 (5), 1123-1135, 2017
312017
Transmembrane AMPA receptor regulatory protein regulation of competitive antagonism: a problem of interpretation
DM MacLean, D Bowie
The Journal of physiology 589 (22), 5383-5390, 2011
312011
Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive
DM MacLean, V Jayaraman
Proceedings of the National Academy of Sciences 114 (12), E2504-E2513, 2017
282017
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