A highly specific SpCas9 variant is identified by in vivo screening in yeast A Casini, M Olivieri, G Petris, C Montagna, G Reginato, G Maule, ... Nature biotechnology 36 (3), 265-271, 2018 | 489 | 2018 |
Physiological protein blocks direct the Mre11–Rad50–Xrs2 and Sae2 nuclease complex to initiate DNA end resection G Reginato, E Cannavo, P Cejka Genes & development 31 (23-24), 2325-2330, 2017 | 129 | 2017 |
The MRE11 complex: A versatile toolkit for the repair of broken DNA G Reginato, P Cejka DNA repair 91, 102869, 2020 | 77 | 2020 |
Stepwise 5′ DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble E Cannavo, G Reginato, P Cejka Proceedings of the National Academy of Sciences 116 (12), 5505-5513, 2019 | 59 | 2019 |
Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres V Spegg, A Panagopoulos, M Stout, A Krishnan, G Reginato, R Imhof, ... Nature Structural & Molecular Biology 30 (4), 451-462, 2023 | 23 | 2023 |
Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2 S Halder, A Sanchez, L Ranjha, G Reginato, I Ceppi, A Acharya, R Anand, ... Molecular Cell 82 (19), 3553-3565. e5, 2022 | 23 | 2022 |
Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation J Dai, A Sanchez, C Adam, L Ranjha, G Reginato, P Chervy, ... Proceedings of the National Academy of Sciences 118 (23), 2021 | 22 | 2021 |
Mre11-Rad50 oligomerization promotes DNA double-strand break repair VM Kissling, G Reginato, E Bianco, K Kasaciunaite, J Tilma, G Cereghetti, ... Nature Communications 13 (1), 2374, 2022 | 19 | 2022 |
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners A Marsella, E Gobbini, C Cassani, R Tisi, E Cannavo, G Reginato, ... Cell Reports 34 (13), 108906, 2021 | 17 | 2021 |
The Pif1 helicase is actively inhibited during meiotic recombination which restrains gene conversion tract length DV Vernekar, G Reginato, C Adam, L Ranjha, F Dingli, MC Marsolier, ... Nucleic acids research 49 (8), 4522-4533, 2021 | 16 | 2021 |
Crossover or non-crossover outcomes: tailored processing of homologous recombination intermediates A Sanchez, G Reginato, P Cejka Current opinion in genetics & development 71, 39-47, 2021 | 14 | 2021 |
Sequence and chromatin features guide DNA double-strand break resection initiation R Gnügge, G Reginato, P Cejka, LS Symington Molecular Cell 83 (8), 1237-1250. e15, 2023 | 9 | 2023 |
Mechanism of replication fork reversal and protection by human RAD51 and RAD51 paralogs P Cejka, S Halder, A Sanchez, L Ranjha, A Taglialatela, G Reginato, ... | | 2021 |