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Iain Hepburn
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STEPS: efficient simulation of stochastic reaction–diffusion models in realistic morphologies
I Hepburn, W Chen, S Wils, E De Schutter
BMC systems biology 6, 1-19, 2012
1662012
Stochastic calcium mechanisms cause dendritic calcium spike variability
H Anwar, I Hepburn, H Nedelescu, W Chen, E De Schutter
Journal of Neuroscience 33 (40), 15848-15867, 2013
482013
The role of dendritic spine morphology in the compartmentalization and delivery of surface receptors
CM Simon, I Hepburn, W Chen, E De Schutter
Journal of computational neuroscience 36, 483-497, 2014
312014
Accurate reaction-diffusion operator splitting on tetrahedral meshes for parallel stochastic molecular simulations
I Hepburn, W Chen, E De Schutter
The Journal of chemical physics 145 (5), 2016
142016
Efficient calculation of the quasi-static electrical potential on a tetrahedral mesh and its implementation in STEPS
I Hepburn, R Cannon, E De Schutter
Frontiers in computational neuroscience 7, 129, 2013
142013
STEPS: STochastic Engine for Pathway Simulation
I Hepburn
Encyclopedia of Computational Neuroscience, 3309-3311, 2022
82022
A model of induction of cerebellar long-term depression including RKIP inactivation of Raf and MEK
I Hepburn, A Jain, H Gangal, Y Yamamoto, K Tanaka-Yamamoto, ...
Frontiers in molecular neuroscience 10, 19, 2017
82017
Modeling neurons in 3d at the nanoscale
W Chen, I Hepburn, A Martyushev, E De Schutter
Computational Modelling of the Brain: Modelling Approaches to Cells …, 2022
52022
26th annual computational neuroscience meeting (CNS* 2017): Part 3
AJH Newton, AH Seidenstein, RA McDougal, A Pérez-Cervera, G Huguet, ...
BMC Neuroscience 18, 1-82, 2017
42017
Accurate approximation and MPI parallelization of spatial stochastic reaction-diffusion in STEPS
I Hepburn, W Chen, E De Schutter
BMC Neuroscience 15 (Suppl 1), P177, 2014
32014
Accurate approximation to stochastic reaction diffusion on unstructured meshes in STEPS
I Hepburn, W Chen, E De Schutter
BMC Neuroscience 16 (Suppl 1), P55, 2015
22015
Improving performance of the STochastic Engine for Pathway Simulation (STEPS)
W Chen, I Hepburn, E De Schutter
BMC Neuroscience 12 (Suppl 1), P58, 2011
22011
Tetrahedral mesh generation and visualization for stochastic reaction-diffusion simulation
W Chen, I Hepburn, E De Schutter
BMC Neuroscience 11 (Suppl 1), P70, 2010
22010
STEPS: reaction-diffsion simulation in complex 3D geometries
I Hepburn, S Wils, E De Schutter
BMC Neuroscience 10 (Suppl 1), P51, 2009
22009
Vesicle and reaction-diffusion hybrid modeling with STEPS
I Hepburn, J Lallouette, W Chen, AR Gallimore, SY Nagasawa-Soeda, ...
Communications Biology 7 (1), 573, 2024
12024
Dynamic regulation of vesicle pools in a detailed spatial model of the complete synaptic vesicle cycle
AR Gallimore, I Hepburn, S Rizzoli, ED Schutter
bioRxiv, 2023.08. 03.551909, 2023
12023
Hybrid vesicle and reaction-diffusion modeling with STEPS
I Hepburn, J Lallouette, W Chen, AR Gallimore, SY Nagasawa, ...
bioRxiv, 2023.05. 08.539782, 2023
12023
STEPS.: Fast and memory-efficient molecular simulations of neurons at the nanoscale
W Chen, T Carel, O Awile, N Cantarutti, G Castiglioni, A Cattabiani, ...
Neuroscience, computing, performance, and benchmarks: Why it matters to …, 2023
12023
STEPS 4.0: Fast and memory-efficient molecular simulations of neurons at the nanoscale
W Chen, T Carel, O Awile, N Cantarutti, G Castiglioni, A Cattabiani, ...
Frontiers in Neuroinformatics 16, 883742, 2022
12022
Dendritic Volume Mesh Reconstruction for STEPS: How Does Mesh Quality Affect Stochastic Reaction-Diffusion Simulation?
W Chen, I Hepburn, E De Schutter
BMC Neuroscience 14 (Suppl 1), P95, 2013
12013
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Articles 1–20