IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin–directed vascular barrier disruption V Langer, E Vivi, D Regensburger, TH Winkler, MJ Waldner, T Rath, ... The Journal of clinical investigation 129 (11), 4691-4707, 2019 | 174 | 2019 |
Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner N Britzen-Laurent, M Bauer, V Berton, N Fischer, A Syguda, ... PloS one 5 (12), e14246, 2010 | 139 | 2010 |
GBP-1 acts as a tumor suppressor in colorectal cancer cells N Britzen-Laurent, K Lipnik, M Ocker, E Naschberger, VS Schellerer, ... Carcinogenesis 34 (1), 153-162, 2013 | 107 | 2013 |
Gamma interferon-induced guanylate binding protein 1 is a novel actin cytoskeleton remodeling factor N Ostler, N Britzen-Laurent, A Liebl, E Naschberger, G Lochnit, M Ostler, ... Molecular and cellular biology 34 (2), 196-209, 2014 | 81 | 2014 |
Specific TP53 mutation pattern in radiation-induced sarcomas N Gonin-Laurent, A Gibaud, M Huygue, SH Lefevre, M Le Bras, ... Carcinogenesis 27 (6), 1266-1272, 2006 | 80 | 2006 |
Matricellular protein SPARCL1 regulates tumor microenvironment–dependent endothelial cell heterogeneity in colorectal carcinoma E Naschberger, A Liebl, VS Schellerer, M Schütz, N Britzen-Laurent, ... The Journal of clinical investigation 126 (11), 4187-4204, 2016 | 72 | 2016 |
Interferon γ-induced human guanylate binding protein 1 inhibits mammary tumor growth in mice K Lipnik, E Naschberger, N Gonin-Laurent, P Kodajova, H Petznek, ... Molecular medicine 16, 177-187, 2010 | 67 | 2010 |
Mechanism of GTPase-activity-induced self-assembly of human guanylate binding protein 1 T Vöpel, A Syguda, N Britzen-Laurent, S Kunzelmann, MB Lüdemann, ... Journal of molecular biology 400 (1), 63-70, 2010 | 62 | 2010 |
Viral inhibitor of apoptosis vFLIP/K13 protects endothelial cells against superoxide-induced cell death M Thurau, G Marquardt, N Gonin-Laurent, K Weinländer, E Naschberger, ... Journal of virology 83 (2), 598-611, 2009 | 62 | 2009 |
A transcriptome signature distinguished sporadic from postradiotherapy radiation-induced sarcomas NS Hadj-Hamou, N Ugolin, C Ory, N Britzen-Laurent, X Sastre-Garau, ... Carcinogenesis 32 (6), 929-934, 2011 | 51 | 2011 |
Interferon gamma counteracts the angiogenic switch and induces vascular permeability in dextran sulfate sodium colitis in mice L Haep, N Britzen-Laurent, TG Weber, E Naschberger, A Schaefer, ... Inflammatory Bowel Diseases 21 (10), 2360-2371, 2015 | 50 | 2015 |
RB1 and TP53 pathways in radiation-induced sarcomas N Gonin-Laurent, NS Hadj-Hamou, N Vogt, C Houdayer, ... Oncogene 26 (41), 6106-6112, 2007 | 50 | 2007 |
Pathophysiological role of guanylate-binding proteins in gastrointestinal diseases N Britzen-Laurent, C Herrmann, E Naschberger, RS Croner, M Stürzl World journal of gastroenterology 22 (28), 6434, 2016 | 48 | 2016 |
Permeability analyses and three dimensional imaging of interferon gamma-induced barrier disintegration in intestinal organoids M Bardenbacher, B Ruder, N Britzen-Laurent, B Schmid, M Waldner, ... Stem cell research 35, 101383, 2019 | 46 | 2019 |
Interplay of GTPases and cytoskeleton in cellular barrier defects during gut inflammation R López-Posadas, M Stürzl, I Atreya, MF Neurath, N Britzen-Laurent Frontiers in immunology 8, 296933, 2017 | 46 | 2017 |
High throughput screening of gene functions in mammalian cells using reversely transfected cell arrays: review and protocol M Sturzl, A Konrad, G Sander, E Wies, F Neipel, E Naschberger, ... Combinatorial chemistry & high throughput screening 11 (2), 159-172, 2008 | 46 | 2008 |
Guanylate binding protein 1–mediated interaction of T cell antigen receptor signaling with the cytoskeleton F Forster, W Paster, V Supper, P Schatzlmaier, S Sunzenauer, N Ostler, ... The Journal of Immunology 192 (2), 771-781, 2014 | 45 | 2014 |
β6‐integrin serves as a novel serum tumor marker for colorectal carcinoma S Bengs, E Becker, P Busenhart, MR Spalinger, T Raselli, S Kasper, ... International journal of cancer 145 (3), 678-685, 2019 | 33 | 2019 |
Structural proteins of Kaposi’s sarcoma-associated herpesvirus antagonize p53-mediated apoptosis P Chudasama, A Konrad, R Jochmann, B Lausen, P Holz, E Naschberger, ... Oncogene 34 (5), 639-649, 2015 | 23 | 2015 |
IFN-γ–Driven Intratumoral Microenvironment Exhibits Superior Prognostic Effect Compared with an IFN-α–Driven Microenvironment in Patients with Colon Carcinoma S Grenz, E Naschberger, S Merkel, N Britzen-Laurent, U Schaal, ... The American journal of pathology 183 (6), 1897-1909, 2013 | 22 | 2013 |