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Christian M. Kaiser
Christian M. Kaiser
Associate Professor, Department of Biology, Johns Hopkins University
Verified email at jhu.edu - Homepage
Title
Cited by
Cited by
Year
The ribosome modulates nascent protein folding
CM Kaiser, DH Goldman, JD Chodera, I Tinoco Jr, C Bustamante
Science 334 (6063), 1723-1727, 2011
3272011
ClpX (P) generates mechanical force to unfold and translocate its protein substrates
RA Maillard, G Chistol, M Sen, M Righini, J Tan, CM Kaiser, C Hodges, ...
Cell 145 (3), 459-469, 2011
3202011
Real-time observation of trigger factor function on translating ribosomes
CM Kaiser, HC Chang, VR Agashe, SK Lakshmipathy, SA Etchells, ...
Nature 444 (7118), 455-460, 2006
2742006
Mechanical force releases nascent chain–mediated ribosome arrest in vitro and in vivo
DH Goldman, CM Kaiser, A Milin, M Righini, I Tinoco Jr, C Bustamante
Science 348 (6233), 457-460, 2015
2432015
Single-molecule studies of protein folding with optical tweezers
C Bustamante, L Alexander, K Maciuba, CM Kaiser
Annual review of biochemistry 89, 443-470, 2020
1492020
De novo folding of GFP fusion proteins: high efficiency in eukaryotes but not in bacteria
HC Chang, CM Kaiser, FU Hartl, JM Barral
Journal of molecular biology 353 (2), 397-409, 2005
1332005
The ribosome cooperates with a chaperone to guide multi-domain protein folding
K Liu, K Maciuba, CM Kaiser
Molecular cell 74 (2), 310-319. e7, 2019
912019
Identification of nascent chain interaction sites on trigger factor
SK Lakshmipathy, S Tomic, CM Kaiser, HC Chang, P Genevaux, ...
Journal of biological chemistry 282 (16), 12186-12193, 2007
892007
The ribosome destabilizes native and non‐native structures in a nascent multidomain protein
K Liu, JE Rehfus, E Mattson, CM Kaiser
Protein Science 26 (7), 1439-1451, 2017
572017
Folding up and moving on—nascent protein folding on the ribosome
CM Kaiser, K Liu
Journal of molecular biology 430 (22), 4580-4591, 2018
462018
Mechanisms of cellular proteostasis: Insights from single molecule approaches
C Bustamante, CM Kaiser, AR Maillard, D Goldman, C Wilson
Annu Rev Biophys 43, 119-140, 2014
462014
Energetic dependencies dictate folding mechanism in a complex protein
K Liu, X Chen, CM Kaiser
Proceedings of the National Academy of Sciences 116 (51), 25641-25648, 2019
382019
The SecA motor generates mechanical force during protein translocation
R Gupta, D Toptygin, CM Kaiser
Nature Communications 11 (1), 3802, 2020
302020
Tracking UNC-45 chaperone-myosin interaction with a titin mechanical reporter
CM Kaiser, PJ Bujalowski, L Ma, J Anderson, HF Epstein, AF Oberhauser
Biophysical journal 102 (9), 2212-2219, 2012
272012
Bayesian hidden Markov model analysis of single-molecule force spectroscopy: Characterizing kinetics under measurement uncertainty
JD Chodera, P Elms, F Noé, B Keller, CM Kaiser, A Ewall-Wice, ...
arXiv preprint arXiv:1108.1430, 2011
272011
Single-molecule chemo-mechanical spectroscopy provides structural identity of folding intermediates
HN Motlagh, D Toptygin, CM Kaiser, VJ Hilser
Biophysical journal 110 (6), 1280-1290, 2016
252016
Next generation single-molecule techniques: Imaging, labeling, and manipulation in vitro and in cellulo
T Ha, C Kaiser, S Myong, B Wu, J Xiao
Molecular cell 82 (2), 304-314, 2022
192022
Probing the Mechanisms of Translation with Force
CM Kaiser, IJ Tinoco
Chemical Reviews 114, 3266-3280, 2014
192014
Synthesis runs counter to directional folding of a nascent protein domain
X Chen, N Rajasekaran, K Liu, CM Kaiser
Nature Communications 11 (1), 5096, 2020
172020
Facile tethering of stable and unstable proteins for optical tweezers experiments
K Maciuba, F Zhang, CM Kaiser
Biophysical Journal 120 (13), 2691-2700, 2021
132021
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