Stebėti
Dr. Nico Fleck
Dr. Nico Fleck
Merck KGaA, Darmstadt, Germany
Patvirtintas el. paštas merckgroup.com
Pavadinimas
Cituota
Cituota
Metai
SLIM: A short‐linked, highly redox‐stable trityl label for high‐sensitivity in‐cell EPR distance measurements
N Fleck, CA Heubach, T Hett, FR Haege, PP Bawol, H Baltruschat, ...
Angewandte Chemie 132 (24), 9854-9859, 2020
892020
Ox‐SLIM: Synthesis of and Site‐Specific Labelling with a Highly Hydrophilic Trityl Spin Label
N Fleck, C Heubach, T Hett, S Spicher, S Grimme, O Schiemann
Chemistry–A European Journal 27 (16), 5292-5297, 2021
452021
Pulsed EPR Dipolar Spectroscopy on Spin Pairs with one Highly Anisotropic Spin Center: The Low‐Spin FeIII Case
D Abdullin, P Brehm, N Fleck, S Spicher, S Grimme, O Schiemann
Chemistry–A European Journal 25 (63), 14388-14398, 2019
272019
Excitation energy transfer and exchange‐mediated quartet state formation in porphyrin‐trityl systems
O Nolden, N Fleck, ER Lorenzo, MR Wasielewski, O Schiemann, P Gilch, ...
Chemistry–A European Journal 27 (8), 2683-2691, 2021
252021
A sustainable synthesis of the SARS-CoV-2 Mpro inhibitor nirmatrelvir, the active ingredient in Paxlovid
JRA Kincaid, JC Caravez, KS Iyer, RD Kavthe, N Fleck, DH Aue, ...
Communications chemistry 5 (1), 156, 2022
242022
C–C cross-coupling reactions of trityl radicals: spin density delocalization, exchange coupling, and a spin label
N Fleck, T Hett, J Brode, A Meyer, S Richert, O Schiemann
The Journal of Organic Chemistry 84 (6), 3293-3303, 2019
242019
Pulsed EPR Dipolar Spectroscopy under the Breakdown of the High‐Field Approximation: The High‐Spin Iron (III) Case
D Abdullin, H Matsuoka, M Yulikov, N Fleck, C Klein, S Spicher, ...
Chemistry–A European Journal 25 (37), 8820-8828, 2019
232019
Synthesis of μ2‐Oxo‐Bridged Iron(III) Tetraphenylporphyrin–Spacer–Nitroxide Dimers and their Structural and Dynamics Characterization by using EPR and MD …
D Abdullin, N Fleck, C Klein, P Brehm, S Spicher, A Lützen, S Grimme, ...
Chemistry–A European Journal 25 (10), 2586-2596, 2019
132019
Improved, Odorless Access to Benzo[1,2-d;4,5-d′]- bis[1,3]dithioles and Tert-butyl Arylsulfides via C-S Cross Coupling
K Kopp, O Schiemann, N Fleck
Molecules 25 (16), 3666, 2020
92020
An environmentally responsible route to tezacaftor, a drug for treatment of cystic fibrosis prepared in water via ppm Au catalysis as entry to 2-substituted indoles
N Fleck, RM Thomas, M Müller, S Grimme, BH Lipshutz
Green Chemistry 24 (17), 6517-6523, 2022
62022
API syntheses in aqueous media: Assessing the environmental footprint en route from academic discovery to industrial applications as “green opportunity” for process chemistry
N Fleck, F Roschangar, AM Haydl
Organic Process Research & Development 27 (5), 822-830, 2023
52023
Magneto‐Structural Correlations in a Mixed Porphyrin(Cu2+)/Trityl Spin System: Magnitude, Sign, and Distribution of the Exchange Coupling Constant
D Abdullin, T Hett, N Fleck, K Kopp, S Cassidy, S Richert, O Schiemann
Chemistry–A European Journal 29 (14), e202203148, 2023
32023
Tris [2, 2, 6, 6-tetramethyl-8-(trimethylsilyl) benzo [1, 2-d; 4, 5-d′] bis (1, 3-dithiol)-4-yl] methanol diethyl ether monosolvate
N Fleck, G Schnakenburg, AC Filippou, O Schiemann
Acta Crystallographica Section E: Crystallographic Communications 74 (4 …, 2018
22018
An Environmentally Responsible Synthesis of the SARS-CoV-2 Mpro Inhibitor Nirmatrelvir (PF‑07321332), the Active Ingredient in Paxlovid
JRA Kincaid, JC Caravez, KS Iyer, RD Kavthe, N Fleck, BH Lipshutz
12022
Intramolecular O—H⋯ S hydrogen bonding in threefold symmetry: Line broadening dynamics from ultrafast 2DIR-spectroscopy and ab initio calculations
P Brünker, LI Domenianni, N Fleck, J Lindner, O Schiemann, P Vöhringer
The Journal of Chemical Physics 154 (13), 2021
12021
Streamlining Catalysis Screenings on a Budget
P Czember, F Weber, A Kokollari, H Spreitzer, N Fleck
Organic Process Research & Development 28 (4), 1145-1150, 2024
2024
Lösungsmittel: Weder Dystopie noch Nirwana
N Fleck
Nachrichten aus der Chemie 70 (3), 28-30, 2022
2022
Cover Feature: Excitation Energy Transfer and Exchange‐Mediated Quartet State Formation in Porphyrin‐Trityl Systems (Chem. Eur. J. 8/2021)
O Nolden, N Fleck, ER Lorenzo, MR Wasielewski, O Schiemann, P Gilch, ...
Chemistry–A European Journal 27 (8), 2554-2554, 2021
2021
4, 5-d′]-bis [1, 3] dithioles and Tert-butyl Arylsulfides via CS Cross Coupling
K Kopp, O Schiemann, N Fleck
Multidisciplinary Digital Publishing Institute, 0
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